Just out📢 Our new paper published in @natmicrobiol.nature.com describes highly potent cross-neutralizing human monoclonal antibodies against H5Nx influenza viruses. Close collaboration with Sara Andrews lab and Tongqing Zhou lab at the VRC. Link to the article: rdcu.be/eKV9T 1/2

Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques https://www.biorxiv.org/content/10.1101/2025.02.21.639368v1

Also last week in @science.org : @kanekiyom.bsky.social, Douglas Reed, Simon Barratt-Boyes, & colleagues show pre-exposure broadly neutralizing #antibody ( #bnAb ) #prophylaxis against a conserved supersite on #influenza #hemagglutinin (HA) stem protects #macaques against #H5N1 infection! #BirdFlu

Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies https://www.biorxiv.org/content/10.1101/2024.11.27.625426v1

📢Hot off the press! Our latest work studying #influenza broadly neutralizing antibody development in humanized mice. Huge thanks to everyone involved in the study🙏 #NIAID #VRC #Ragon #Scripps www.cell.com/cell-reports...

Hot off the press! Our latest paper on #influenza neuraminidase (NA) antibodies has just been published in Immunity. Lederhofer et al. Isolated and characterized human antibodies to the NA ‘dark side’ that are broadly cross-reactive and protective. www.cell.com/immunity/ful...