For 50 years, Voyageurs National Park has brought millions of people from around the world to see all that the Land of 10,000 Lakes has to offer - remote island camping, paddling, world-class fishing, and abundant winter activities. Happy birthday, Voyageurs!

Yesterday, I fondly remembered my dear friend Leonard Nimoy, who would have turned 94. His legacy lives on in our hearts. Just days ago, Bill Shatner celebrated his 94th birthday — wishing him continued health and happiness. Live long and prosper, my friends.

New publication from the lab! We used a machine learning approach to predict chromatin loop dynamics during human spermatogenesis - and find these structures do not direct gene expression but may drive the positioning of recombination events bmcbiol.biomedcentral.com/articles/10....

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This is great

TUTORIAL: Our new preprint "Clinical progression of clonal hematopoiesis is determined by a combination of mutation timing, fitness, and clonal structure" is out @elatorre.bsky.social @edinunilbc.bsky.social @linusschumacher.bsky.social @biologyaging.bsky.social www.biorxiv.org/content/10.1...

This is very disturbing for Equity Diversity and Inclusion in the UK. www.theguardian.com/business/202...

🔥 New Fraticelli lab publication🔥 “Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemia driver mutations” Now at Cell Stem Cell, with two new figures, in vivo, and sequential mutagenesis data. Performed with the support of Cris Cancer and @erc.europa.eu

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NEW: Minnesota was just ranked a top state both to retire and to raise a family.   By investing in the things that matter – economic opportunity, health and safety, and strong communities – we’re building the best state for all Minnesotans from childhood through retirement.

It was an honor to sign the guest book in the home of Anne Frank. I was here as a younger man and thought about her life as a dark chapter of history. Today, I can’t help but think of her story as one of caution. Our world is fragile, and it’s incumbent on us not to break it.

First nuclear weapons management, now this. No one - Democrat or Republican - voted for this kind of incompetence.

A little MYC goes a long way! Check out this absolute tour de force from colleagues Miryam Müller, Stephanie May, Tom Bird and team who assembled an compendium of liver cancer mouse models mirroring a spectrum of human HCC subtypes: www.nature.com/articles/s41...

The flying public needs answers. How many FAA personnel were just fired? What positions? And why?

Interested in an early-career fellowship (within 3 years of a PhD)? Want to work at the interface of AI with biology, health or medicine? Contact me if you want support with your application www.bmh.manchester.ac.uk/research/sup...

New paper. Why do we try to remove increasingly large numbers of lymph nodes in colon cancer surgery? Here we follow up our BJC 2022 paper with ~370K patients in England and USA. Only 9 LNs are required to stage the cancer. www.nature.com/articles/s41...

Do you love software engineering for exciting biological applications, open science,open source, R, Bioconductor, modern web, cloud& ML technologies? We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

A useful tool and a great thing to do... 5calls.org/issue/nih-ns...

We’re focused on feeding our kids. Investing in our schools. Making sure child care is affordable. Regardless of the chaos unfolding in Washington, we’re making Minnesota the best state for kids to grow up.

Danke Mutti🙏🏾

What DNA variants alter transcription factor (TF) binding affinity? Here, we describe a new workflow baal-nf. We used it to trawl through 6017 ChIP-Seq data sets for 558 TFs and 46 genotyped cell lines, finding 298,783 allele-specific binding sites (ASBs). www.biorxiv.org/content/10.1... 1/2

Happy holidays and Happy New Year from the Generation Scotland team!🎄🎇 We had a ✨competitive✨ darts game to celebrate—check out these great pics! A huge thank you to our amazing volunteers; we’re so grateful for you and excited for 2025, with exciting research and events! We'll be back on Jan 3rd. ❤️

This is a catastrophe. While Finland has downgraded the MDPI and Frontiers journals to level 0 (meaning these publications are not recognized for research evaluation purposes), Germany has signed an agreement to promote publications in MDPI journals.

I was approached re: the Finnish decision to downgrade MDPI & Frontiers journals in 🇫🇮 rankings (THE article). This decision was based on broad patterns, including in our recent study "The strain on scientific publishing" (link: direct.mit.edu/qss/article/...) A quick 🧵 1/n #SciPub #AcademicChatter

Just a reminder that in 2019, RFK Jr.'s anti-vaccine misinformation campaign helped cause a measles outbreak in Samoa that killed 83 people, mostly kids. Do you really want him to lead the Department of Health and Human Services?

Infamous paper that popularized unproven COVID-19 treatment finally retracted Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds @cathleenogrady.bsky.social reports. www.science.org/content/arti...

The December issue of the Disconnected Mind Newsletter from Lothian Birth Cohorts is now available online with highlights of 2024 as well as our recent research and publications, and scientific and public engagement events from this Autumn: edin.ac/3DeEOCR @schoolofppls.bsky.social

Cancer is a common cause of line-of-duty death for firefighters. We worked across the aisle to reauthorize the Firefighter Cancer Registry so we can improve research into health and safety standards for these heroes who put their lives on the line for us every day.

We've been awarded a UKRI MRC grant to examine the causes and consequences of #heterochromatin hypomethylation in cancer 🥳. #postdoc opportunity coming in the near future. #epigenetics. Please share with anyone who might be interested.

Here's Toby Young defending Elon Musk's FRS. www.spectator.co.uk/article/why-... I suspect he feels common ground: www.theguardian.com/media/2018/j... Since he says my arguments are political (they aren't) and doesn't link to my post, I wonder if he's read it. deevybee.blogspot.com/2024/11/why-...

#Phd on #Aging #Ageing available in my group. Focus is long-read sequencing and splicing after treatment with DR and mTOR suppression in flies. #drosophila www.findaphd.com/phds/project...