Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development in mice Olga A. Guryanova & team report an aging-related condition caused by mutations in the blood system promotes obesity and drives the risk of #diabetes & #MASLD with a high-fat diet: doi.org/10.1172/JCI1...

The function of blood stem cells is critically governed by their dynamic, bidirectional interactions within the bone marrow niche. When these cells turn leukaemic, the crosstalk with their environment changes dramatically, fuelling disease progression. www.findaphd.com/phds/project...

Join us in York 🇬🇧 for the 1st Advances in Experimental & Therapeutic Haematopoietic Stem Cell Expansion (HExaT) Meeting! 📅Workshops + 1-day scientific programme 🎙️ Keynotes: Yamazaki, Laurenti, Nakauchi, Essers, Schroeder 🧬 Registration: sites.google.com/york.ac.uk/h... #HExaT2025

New opportunity - this is a non clinical PhD 4 year program - have a look and DM me if wish to discuss this particular student ship in modelling high risk Leukemia. If that doesn’t take your fancy - there are plenty of exciting projects here!

Many cancers begin as precancerous conditions. But what happens when these early cells coexist with a full-blown tumour? Join us for an MRC funded PhD studentship exploring how primary cancers influence the evolution of precancerous cells. www.findaphd.com/phds/project...

We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...

Today is the last day for discounted registration! We have space for 3-4 more posters...shoot me an email if you would like to present a poster! [email protected]

Huge congratulations to Yu-Hung Wang, who has been honoured with the Best Outstanding Research Contribution Award from the FBMH Doctoral Academy at the University of Manchester! We are incredibly proud of Yu-Hung's dedication and hard work!

Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF

Hey #HemeSky and #EpiSci folks! We are hiring! For our Translational Cancer Epigenomics team @dkfz.bsky.social and @nct-heidelberg.bsky.social we are looking for a talented postdoc interested in research on heme malignancies and #epigenetics. Interested? 👉See jobs.dkfz.de/en/jobs/1676... or DM me!

Just over 24 hours to get your abstract submitted

Excited to share our work published in Stem Cell Reports! www.cell.com/stem-cell-re... This work was primarily led by Samiyah Shafiq, PhD, with co-supervision from Georges Lacaud @cruk-mi.bsky.social and Jon @The Cell Fate Engineering and Therapeutics Laboratory

💥Exciting new #postdoc opportunities in my lab at @cruk-mi.bsky.social i.bsky.social to study #NutrientHostMicrobiome interactions in #CancerImmunity in mice and humans. #CancerImmunology#MucosalImmunology#Microbiome ⏰Deadline: 4 April 2025 Apply👇 www.cruk.manchester.ac.uk/career/mi-24... ⏩RT

www.biorxiv.org/content/10.1... In this preprint, we showed that granulocytes from CMML patients are immature and produce high levels of an adipokine called Resistin. Resistin binds to monocytes and prevents their maturation, potentially contributing to the monocytosis phenotype in CMML.

CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity in my lab using unique pt models ‘Phosphatases in melanoma metastasis +therapy resistance’ 📅 Deadline: 4 April 🔗https://www.crukcentre.manchester.ac.uk/opportunities/the-role-of-phosphatases-in-melanoma-metastasis-and-therapy-resistance/

Find out more about our #PhDStudent program, currently recruiting for an exciting position in our Stem Cell Biology Research Group: "Development of Novel Cellular Platforms for Immunotherapies" Full details and link to apply 👇 www.cruk.manchester.ac.uk/phd-student-... #CancerResearch #PhD

PhD applicants of Black or mixed Black heritage are encouraged to apply to our lab via the Crick's inaugural recruitment for Future Leaders in Biomedical Sciences Scholarships. www.crick.ac.uk/careers-and-...

Interested in investigating the principles that regulate the establishment of tumour environments that promote or inhibit the anti-tumour function of the immune system? Our group is currently recruiting a postdoctoral fellow. Learn more about our research 👇 www.cruk.manchester.ac.uk/research-gro...

We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social DM me for inquiries pl apply/share tinyurl.com/m6jnksk5

OK folks, I have now created a google form that allows people to sign to show their support for my open letter to the President of the Royal Society. Please sign and share widely: forms.gle/miDciq35oxyw...

🧪Later TODAY, we have the next installment of our DCS Next-Gen Seminar Series with Dr William Grey, MRC Career Development Award Fellow from The University of York. 🔬The Grey lab studies the role of proteostasis in healthy and malignant stem cells, predominantly in the haematopoietic system🧬

“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av

We are pleased to announce the publication of our research in Cell Reports Medicine. The study focuses on the stratification of secondary AML patients previously diagnosed with chronic myelomonocytic leukaemia. www.sciencedirect.com/science/arti...

If you're a medical student at The University of Manchester, St Andrews School of Medicine or University Of Leeds - School Of Medicine and are looking to combine your clinical training with a research PhD, then check out our latest opportunities. 🧑‍🔬🧪 👉 lnkd.in/eQ_KiSPq

Part of the thesis work from my first graduate student has been published in the journal Leukemia. www.nature.com/articles/s41...