More structural biology! From the @jburkevic.bsky.social lab with work from @sushantsuresh.bsky.social and @alexlouiseshaw.bsky.social - featuring data collected in our facility! #cryoEM www.jbc.org/article/S002...

Final part of my PhD work is now out! We were able to develop a nanobody that inhibits EFR3 mediated PI4KA membrane recruitment. Potential therapeutic idea? Amazing collaboration with different labs using a host of different techniques. @alexlouiseshaw.bsky.social

Great collaborative work where we developed a nanobody based tool to block EFR3 mediated recruitment of PI4KA. A potential therapeutic window maybe? Thanks @alexlouiseshaw.bsky.social for the assist!

New preprint from the lab headed up by @sushantsuresh.bsky.social! Late last year, we published the molecular basis of PI4KA plasma membrane recruitment by EFR3 (PMID:39705356). This work builds on these findings and identifies a new potential therapeutic avenue! Check it out!

Back from vacation and really glad to share some work from my PhD research. Great collaborative effort @alexlouiseshaw.bsky.social Check out this post from my PI to learn more about Lipid kinase PI4KA and its regulation!