The @fda.gov has put out a Request for Public Comment on Repurposed Medications -- with a focus on rare diseases! This is a perfect time to chime in & raise awareness of #LongCOVID. A few people from our Subreddit have already submitted comments - check out what people are talking about here! 👇

Happy to share that, after a prolonged peer-review process, our review on the major Neuroinflammatory events in #LongCovid was accepted for publication in Translational Psychiatry by @natureportfolio.nature.com! Coming out soon, but preprint available here: www.preprints.org/manuscript/2...

New Mass General Brigham study finds rate of Long COVID much higher than we think In this new study, researchers used an AI tool to track how many people tested positive and then later sought care for health problems linked to LC. The number came out at 16% - higher than most estimates. 1/

FDA approves Xocova (ensitrelvir) as post-exposure prophylaxis of SARS-CoV-2! www.fda.gov/drugs/novel-... 1/

This is terrific. Japanese-made Ensitrelvir (Xocova) can prevent covid in people who have been exposed to the SARS-CoV-2 virus.

👉Finnish study finds Long COVID associated with changes in brain activity, rather than inflammation 🧠 This study showed some different results than what we typically see. Researchers did NOT find signs of increased inflammation in LC patients’ brains, compared to healthy controls. 1/

New study finds ensitrelvir (Xocova) and molnupiravir - but not Paxlovid- reduce Long COVID rates if taken during acute infection 💊 Here's a super interesting study out of Japan. Researchers gave one of the 3 above antivirals to patients during their acute COVID infection. 1/

New @thelancet.com paper addresses ethical dilemmas in #LongCOVID research Should researchers: 👉Urgently funding clinical trials of potentially disease-modifying treatments 👉Continuing to build our understanding of the disease - which could let us more accurately subgroup patients? 1/

Amazing to see Men’s Health interview leading Long COVID researcher Dr. Michael Peluso of UCSF! Dr. Peluso explains why he believes we will someday have a cure for LC- and why he’s excited to get up every morning! ☀️🙏 www.menshealth.com/health/a7113...

Powerful op-ed from Dr. Robert Redfield, who was CDC director during the first Trump administration. As a physician, he says "Today, much of my medical practice is focused on helping patients afflicted with Long COVID." 1/ www.foxnews.com/opinion/inno...

The latest episode of #StillHere is out now! We spoke with reporter Jamie Ducharme about her feature on the underreporting of #LongCOVID around the world. The episode also features advocate Mlindeni Gabela, on the stigma of the disease in South Africa. thesicktimes.org/2026/04/30/p...

Fascinating new research from @solveme.bsky.social What is going on with T cells in Long COVID and ME/CFS? 🤔👇 In this talk, researchers Dr. Liisa Selin, Dr. Ayano Kohlgruber, and Dr. Roshan Kumar discuss their newest work, arguing that dysfunctional T-cells are driving #MECFS and #LongCOVID. 1/

Very interesting 🧵 by @longcovidlabs.bsky.social on XTwitter (didn't see it posted here yet): "Here's a great roundup on what the Long COVID Community has learned from recent clinical trials, from the always insightful @CortJohnson Definitely worth..." Full 🧵 threadreaderapp.com/thread/20492...

Germany University Hospitals Essen and Bochum, 61 patients, COVID-19 was linked to EBV reactivation in at least 68% with weakened CD8 T cell responses, suggesting immune exhaustion may allow latent viruses to resurface. link.springer.com/article/10.1...

Important new paper from Steifman et al. looking at blood-based biomarkers of Long COVID in children and young adults (which quite possibly apply to adults too!). 🩸🦠 1/

Why gets Long COVID, and why? Why do Latinos appear to be at higher risk- and can environmental exposures increase risk? Important article from The Spokesman Review examines LC in Latino agriculture workers and questions the possible link to pesticide exposure 1/

Mass General Hospital 84 participants study suggests long COVID may persist because spike related immune complexes overactivate neutrophils which release DNA traps that damage blood vessels and promote microclots sustaining inflammation. www.nature.com/articles/s41...

New study examines the role of lymphocytes in Long COVID 🩸 Pretty exciting new preprint! Here, researchers examined the activity and function of lymphocytes - white blood cells that are part of the immune system. 1/

Can senescent cells be driving smell loss in Long COVID? 🧠 In a new paper, Tsuji et al. look at a new potential cause of LC smell loss - senescent cells in the olfactory mucosa. 1/

Invivyd's new monoclonal VYD2311 shown to be effective against emerging SARS-CoV-2 variants VYD2311 is Invivyd's new monoclonal antibody. It was designed for pre-exposure prophylaxis in immunocompromised adults, however they're also studying it for Long COVID as well. 1/

Photobiomodulation (Red Light Therapy) for Cognitive Dysfunction in Long COVID 🧠 This new study found a red light device called the Vielight led to improvements in cognitive dysfunction, compared to placebo Why would this be effective? 1/

RECOVER Ivabradine Clinical Trial Fails to Show Benefit in #LongCOVID POTS Why is this? 👉 Could it be because study designed failed to account for different POTS subtypes? 👉Are patients' POTS symptoms caused by Microclots? More info here: 👇

Such important info here! Anecdotally, we know of many people who still developed LC even after taking Paxlovid, so the findings are disappointing - if not terribly surprising. However, this is great information to have. Now, we know to focus on other prophylactic treatments such as Metformin.

Platelet-to-Lymphocyte Ratio as a Biomarker of Brain Metabolism in LC 🧠 This fascinating study out of Poland investigated whether there's a correlation between brain fog in Long COVID, and immune markers that can be measured in the blood. To measure brain fog, they assessed patients using: 1/

Study examines V/Q scans in Long COVID patients with lung dysfunction 🫁 This study examined the lungs of 217 Long COVID patients with persistent respiratory symptoms following their acute infection. 1/ link.springer.com/article/10.1...

Monash and Bond University researchers reviewed 14 long COVID treatments (antivirals, metformin, IVIG, mAbs, etc) and found the evidence is still thin. Only 6 had any randomized trial data, and none had enough proof yet to guide treatment decisions. www.frontiersin.org/journals/med...

New preprint shows spike protein persisting in the GI tract - and how it affects the environment around it 🦠 Wow! A lot to unpack here. This team performed gut biopsies and found spike protein in the GI tract of Long COVID patients. 1/ www.biorxiv.org/content/10.6...

✨Long COVID Labs is excited to announce that our Patient Registry is now officially open! ✨ For so long, the Long COVID community has only had anecdotes. Sparks of hope shared in social media. Now we move to the next phase: high-quality scientific evidence. Read more here: bit.ly/4sFX9NC

📢 Clinical trial shows 14 days of metformin has no impact on Long COVID symptoms In this double-blind, placebo-controlled, randomized clinical trial, South Korean researchers tested whether metformin or ursodeoxycholic acid (UDCA) worked to treat Long COVID symptoms. 1/

📣 Long COVID Labs Patient Grant Fund Update Attention all: Our Patient Grant Fund still has limited funds remaining for patients who need help accessing Long COVID treatments! If you are interested in trying a Long COVID treatment that you're unable to afford, our Grant Fund can help! 1/

New study shows relationship between intestinal dysbiosis and neurological symptoms in LC 🦠🧠 Over the years, we have seen some Long COVID patients report dramatic improvements with microbiome-based interventions. This study provides a possible explanation as to why. 1/

COVID is not “just a cold.” Even mild or asymptomatic infections can cause lasting health effects, damaging blood vessels and organs, affecting the brain, and weakening the immune system.

Important - but sobering - article on Covid's neurological impacts. It's unfortunately quite rare to see mainstream news articles talking about the risks of COVID with this degree of seriousness - highly recommend you check this article out! 👇

It's just around the corner... #LongCovidAwarenessDay On X (because BS doesn't have Spaces), March 15th- 20 guest speakers ALL in 24 hrs. Names like- J Howard, M Hoerger, J Sullivan, E Justin, Y BarYam and many more... More info to come. @longcovidlabs.bsky.social @thewhn.bsky.social

New in @bmj.com Neurology! Australian researchers designed a new, non-invasive testing protocol to diagnose small-fiber neuropathy in Long COVID patients. 👇 1/ neurologyopen.bmj.com/content/8/1/...

Really exciting to see Long COVID making it into multiple major news platforms this week! 🙏 Here, the Boston Globe shares the story of Samantha Crausman, a severe LC patient in her late 20's. 1/ www.bostonglobe.com/2026/02/20/m...

Clip from a WDR German TV report: Pascal Hilgruber developed ME/CFS following a Covid infection or vaccination. He now spends 80–90% of his day in bed and says being able to go to the toilet on his own feels like an achievement.

Poignant article highlighting one woman's experience with Long COVID. From Savannah Brooks for @theguardian.com Brooks asks, many people all over the world are suffering in similar ways, whether they realize it's due to Covid or not? 1/

German news segment highlights plight of severe #MECFS #LongCOVID patient Martha's story is absolutely heartbreaking 💔 It's so important to have news outlets raising awareness - please share if you are able! 🙏

In immunocompromised patients, persistent COVID often fails single-drug treatment. Madrid study shows combination therapy (Remdesivir + Paxlovid ± Sotrovimab) clears infection and overcomes resistance. buff.ly/tqlmc0I Personalized antiviral strategies matter. #medsky #IDsky #publichealth #oncsky

Why does Long COVID brain fog seem to affect more patients in the US? 🧠 A recent Northwestern University study surveyed 3,100 long COVID patients from around the world. 🌏 Patients in the US reported symptoms such as brain fog and mental health effects at much higher rates... 1/ bit.ly/4bNfFhN

UCSF: Solving Long COVID: How Decades of HIV Research Paved the Way 🙏 Great article on how the HIV research team at University’s of California San Francisco uses their decades of expertise to expand to Long COVID 👇 www.ucsf.edu/news/2026/01...

Evidence is building: metformin appears to help prevent Long COVID 💊 A new review from U. of Minnesota Medical School highlights multiple studies showing that starting metformin during or soon after acute COVID infection could lower the risk of Long COVID by roughly 40–60%.🦠 1/ bit.ly/4r6A3PQ

New research suggests a simple blood test may help detect lingering lung damage after COVID-19.🩸 A UK study found elevated levels of the two blood biomarkers in people with persistent lung abnormalities months after hospitalization. 🧬👇 1/ medicalxpress.com/news/2026-01...

BBC News: Long Covid and ME patients 'hopeful' about Rosetta Stone study Check out this comprehensive article looking at a new study, with £1.1 million in funding from the UK-based @meassociation.org.uk! 1/ bbc.co.uk/news/articles/cy8pnggl7zgo

Long COVID researcher Yong Chen, PhD, wins prestigious Clinical Research Forum Award! Dr. Chen received the Award for his paper: "Long COVID Associated with SARS-CoV-2 Reinfection Among Children and Adolescents in the Omicron Era (RECOVER-EHR).” 1/

Possible new alternative to Paxlovid is on the horizon! 🙏 Traws Pharma is developing a new anti-SARS-CoV-2 antiviral called Ratutrelvir, as a possible alternative to Paxlovid. 💊 1/

Australia allocates $120 million AUD into Medical Research Future Fund (MRFF) that includes Long COVID! Super encouraging! 🙌🙌🙌 The MRFF will support 60 health and medical research projects aimed at improving prevention, diagnosis, treatment, and care of various diseases. 1/

MIT's MAESTRO study is looking for a few more #LongCovid male participants in the 18-28 yrs & 56-65 yrs brackets. See below screenshots for more info on Long Covid research study from posts by @immunofever.bsky.social & talresearchgroup.mit.edu/mitmaestro #medsky