Analyses of open health datasets can offer valuable contributions to health & medicine, but recent years have seen a proliferation of papers lacking robust or novel findings. In this Editorial, we provide guidance for conducting & reporting high-quality analyses using open datasets🧪 plos.io/4poBmZo

Did you know that you may be eligible to publish in PLOS Medicine without paying an APC? All PLOS journals offer several APC-alternative business agreements through institutional partnerships.📝🧪 To learn more and find out if your institution has an agreement, visit: plos.org/libraries/pa...

In recognition of World AIDS Day 2025, this Perspective by Gregory Folkers & Anthony Fauci reflects on progress made in #antiretroviral treatments & prevention of HIV/AIDS, highlighting promising therapeutic developments and looking ahead to what is needed to end the #AIDS epidemic 🧪 plos.io/48np3Fu

We are pleased to sponsor the online seminar, "Global Health After the Breakpoint: Evidence for What Comes Next", featuring a panel of experts to discuss the future of global health. It's not too late to register using the link below! 🧪 📆 Tuesday 2nd Dec 🕐3.00-4.30pm GMT duke.zoom.us/webinar/regi...

We pride ourselves on our commitments to open science, integrity, and equity in research. If you want to learn more, this Editorial by Executive Editor Helen Lumbard & Editor-in-Chief Till Bärnighausen outlines our scope and vision, and reaffirms our drive for meaningful change 🧪 plos.io/3XFZfzg

PLOS Medicine is now on Bluesky! 🦋 Go and give us a follow 😀⬇️ #MedSky #PLOS

😃 to share this new @plos.org Medicine 📄 written in collaboration with the super cool @kahin-tai.bsky.social (from the super cool @sharectd.bsky.social doctoral network), Gérard Legoff, @annelelouarn.bsky.social & @synthymama.bsky.social.

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

In our latest Editorial, PLOS Medicine Executive Editor Helen Lumbard and I call for the scientific community to tackle research fraud and paper mills head on by creating robust systems of data sharing and transparency 🧪 #PLOSMedicine #datasharing #openscience @plos.org 📄➡️ plos.io/4nDKQ2c

We are proud to announce a new agreement with @rorinstitute.bsky.social and @aimosinc.bsky.social to become a partner journal with MetaResearch Open Review (MetaRoR) @metaror.bsky.social #metaresearch #openscience 🧪 Learn more: plos.io/45wPZB9

Charting the future of PLOS Medicine – in their Editorial, Executive Editor, Helen Lumbard, and Editor-in-Chief, Till Baernighausen, outline their vision for the journal’s next chapter and reaffirm its commitment to diversity, openness, and actionable science. 🧪 ➡️ plos.io/41mvhTx

Our new Collection on #cancer is out now! We delve into how #omics technologies are helping researchers to better understand what goes on in the tumor microenvironment 🧪 See 🧵⬇️ for more info on the articles 1/9 plos.io/4mgHDEw

What links #migraine aura and #headache? In this Essay, Anders Hougaard, Messoud Ashina &co delve into the mechanistic and pathophysiological relationship between migraine aura and headache. 🧪 plos.io/3HUaY8I

It was so nice to visit my old stomping ground in Exeter visiting the @lsiexeter.bsky.social and to give a talk about working in publishing and being an editor at @plos.org as part of the LSI Career Day 📖 And great to see some old colleagues and my PhD supervisor @scholpplab.bsky.social again!

Our latest editorial in defense of #vaccines and vaccination introduces two Perspectives on priorities for outbreak vaccination, as well as the important successes of vaccines to date ⬇️ plos.io/4lKHvxy plos.io/4lLQqio plos.io/3RSlwr3 Please read and spread the word this #WorldImmunizationWeek 💉

#DevBio job opportunity! Development (@dev-journal.bsky.social) is looking for a new Community Manager to run our community site, the Node (@the-node.bsky.social) – a great opportunity if you love devbio, #stemcells, #scicom and community engagement. Happy to chat informally about the role. ⬇️

Vacciness have saved > 6 lives/min in the last 50 years, yet their importance & safety is often questioned “We should not allow misinformation, disinformation, ignorance and defunding to hinder vaccine development, deployment and use” My latest @plosbiology.org journals.plos.org/plosbiology/...

Our latest editorial in defense of vaccines and vaccination, introduces two Perspectives in this issue on priorities for outbreak vaccination, as well as the important successes of vaccines to date Please read and spread the word 🙏🏻!

How did #vocal communication come to dominate human #language? This Unsolved Mystery discusses evidence suggesting that fetal auditory development & learning in the womb are important factors that contributed to human language evolving via a vocal, rather than gestural, route 🗣️🧪 ▶️ plos.io/3EjnKMT

🌍🔬 📣 Please spread the word! Join us! How can cell biology shape a more resilient planet? Virtual registration is still open for the EMBO Workshop on Cells 4 Climate Resilience → meetings.embo.org/event/25-cli... 🗓️ Deadline: April 11 🎥 Watch the teaser → youtu.be/8eMJ91udHDs @embo.org

Can we ever have too much #ecological field #data? This Perspective advocates for proper funding and resources to enable collection of long-term ecological data, which is essential to assess animal behavior and adaptation in the face of anthropogenic change 🧪 ▶️ plos.io/44ir6tZ

Looking forward to this webinar with @scilifelab.se on navigating open science policies. I will speak about open science practices at scientific journals. There’s still time to sign up - come join us! www.scilifelab.se/event/plos-a...

Find out the ins and outs of Registered Reports at the Responsible Research #FREEwebinar on 30 April Join to learn what a registered report is & how it differs from other publication formats, & the benefits of registered reports for authors & science Find out more & register at: lnkd.in/ed3csppN

The coming decade might see major cuts to US Government #funding for biomedicine. This Perspective highlights how your biosciences #PhD gives you the problem-solving skills to navigate this maelstrom, especially if you maintain flexibility, optimism &enthusiasm for uncharted paths🧪 ▶️ plos.io/3XEKPjt

Soil #biodiversity is critical for the health of humans, animals & the environment. However, global change threatens our soil ecosystems. This Essay discusses the importance of soil biodiversity in the face of global stressors & the major knowledge gaps precluding its conservation🧪 ▶️ plos.io/4hSbLUa

"after all, scientists are problem-solvers. If the solution was easy, wouldn’t we have figured it out by now?" Check out my Editorial w/ @npariente.bsky.social discussing portable peer review, reviewer pools, AI, paying reviewers... &other solutions proposed for making peer review more sustainable🧪

Multiplexed imaging is a powerful approach in spatial biology, but is complex, expensive & labor-intensive. This Community Page presents the IBEX Knowledge-Base, a central resource for reagents, protocols & more, to enhance knowledge sharing & innovation of multiplexing techniques.🧪 plos.io/41FoJP9

Insect vector #microbiomes make promising targets for controlling vector-borne diseases. This Perspective discusses how microbial isolate collections aid in identifying microbial targets, & outlines how international collaborations should ensure ethical & equitable benefit sharing🧪 ➡️ plos.io/4isrYAa

Really enjoyed editing this one - a very thought-provoking Essay that eloqeuntly challenges the somatic mutation theory and the notion that cancer is a purely genetic disease 🧪

Science under siege: protecting scientific progress in turbulent times journals.biologists.com/dev/article/...

A major challenge in natural-product-based drug discovery is identifying gene clusters most likely to specify new chemistry & bioactivities. In this Perspective @marnixmedema.bsky.social & @gillesvanwezel.bsky.social discuss the challenges & state of the art of antibiotic discovery🧪 plos.io/4bpZrJa

PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry. plos.io/3D4O8cH

In 2025, we continue to advocate for policy based on scientific evidence. This 2020 Editorial, “We need leaders that believe in scientific evidence”, resonates today as loudly as ever: plos.io/34lyl59. PLOS Biology also continues to push for DEI and a diverse scientific community: plos.io/3rzxczU 🧪

#GitHub, a platform widely used in software development, offers a robust framework for documenting all activities of laboratory research projects. This Community Page highlights the benefits of, and provides guidance for, incorporating the GitHub ecosystem into wet lab workflows. 🧪💻 plos.io/4i1LWkV

Common #altmetrics indices are limited and biased in the social media that they cover. This Perspective highlights how and why altmetrics should broaden its scope to provide more reliable metrics for scientific content and communication. 🧪 plos.io/4jRq5OL

The first @plosbiology.org issue of the 2nd quarter of this century! Papers on fish recombination, neuroscience of syntax, rats vs robots, sensing food hardness, liver zonation, HPV dynamics, SARS-CoV-2 mRNAs, O2 in early evolution, harmful terminology, retractions and much more! plos.io/4aK2Pyh

This really is an insightful collection on a topic @plosbiology.org is keen to support Have a look and tell us what you think! ⬇️ #KSFutureAg25 #KSSustainFuture25 🧪🌱🌾🌽

Our @plosbiology.org December issue wraps up 2024 - papers about evolutionary gearshifts, viral spreading, representing abstract goals, K+ hotspots (see pic), coffee wilt, TB drugs from fungi, cilia & melanogenesis, asymmetric cell division, hyperspectral imaging, etc... plos.io/4h7I81c

The structure of the early metabolic network is unknown. In this Perspective, the authors report that #pentose utilization pathways form all life-essential precursors, speculating that pentose #metabolism could have been a central structural element in early metabolism. plos.io/3BWz68q

What role do #oligodendrocytes play in #Parkinson's disease progression? In this Unsolved Mystery, @sjaekel.bsky.social and colleagues highlight what is and isn't known about oligodendrocytes in PD, and discuss whether they are bystanders or drivers of PD pathology. plos.io/408mdjA

If you're just getting back on Bluesky, welcome to 2025! Here's a 🧵 on the editors' highlights of the stuff that we published in @plosbiology.org last year, compiled in this v nice editorial by @droutledge.bsky.social ...

It’s been amazing working in the PLOS Biology family this year. Here’s my two cents reflecting on 2024 for the journal and the life sciences 🧪: plos.io/3BqPSwc

✨Greetings, life-science community! Excited to see familiar faces here✨ We're Review Commons - a platform for high-quality, journal-independent peer review in the life sciences #OpenScience #preprintpeerreview Stay tuned—Review Commons will be sharing content. We can’t wait to connect with you!

England is so grey this time of year, that the sun coming out and lighting up the room made me jump... 🤦‍♂️ can we fast-forward to summer? ☀️

#Bioremediation using synthetic #microbiomes offers significant advantages over traditional single‐strain‐based approaches 🧫🦠. This Perspective outlines 5 important considerations for the rational design of pollutant‐degrading microbiomes for enhanced bioremediation: plos.io/3ZZbBEA

PLOS journals & editors are increasingly on BlueSky Will keep updating this starter pack 👇🏾 go.bsky.app/5nHQzbg

Right on time for December - a fun and festive way to teach the public about scientific reproducibility 🎄🎄 plos.io/49z4ZQy