Eduardo Marbán, MD, PhD
@eduardomarban.bsky.social
📤 178
📥 239
📝 32
Executive Director,
@SmidtHeart.bsky.social
at Cedars-Sinai Medical Center Views are my own.
reposted by
Eduardo Marbán, MD, PhD
Ying Ge
2 months ago
#AHA25
also congratulations to
@eduardomarban.bsky.social
for receiving the George Brown lectureship and Jiang Chang for the Thomas Smith lectureship! Well-deserved ❤️🎉👍🙌
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Delighted to welcome these three new stars to our faculty: Stephen Nageotte and Mark Sklansky to our congenital heart program, and Eli Friedman to lead
#SportsCardiology
!
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4 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
6 months ago
For the 12th year in a row,
@smidtheart.bsky.social
has been ranked #1 in California for Cardiology, Heart, and Vascular Surgery by
@usnews.com
!
www.cedars-sinai.org/newsroom/ced...
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Fascinating
@smidtheart.bsky.social
research seminar by Farah Sheikh of
@ucsandiego.bsky.social
on
#ARVC
—
#BenchToBedside
journey towards AAV gene therapy with PKP2, now in clinical trials!
8 months ago
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Our lab hosts a few select UCLA
#undergraduates
as
#interns
. One of our stellar interns, working with
#postdoc
Junlang Li, just presented her work at the Undergraduate Research & Creativity Showcase—
#EVs
from
#iPSCs
— check it out!
youtu.be/ElnJW6-UrqQ
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Medical Research: Prerecorded - Panel 9 - Presentation 4
YouTube video by UCLA Undergraduate Research Centers
https://youtu.be/ElnJW6-UrqQ
8 months ago
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Congrats Sumeet!
www.beckershospitalreview.com/hospital-exe...
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8 months ago
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reposted by
Eduardo Marbán, MD, PhD
The American Society for Clinical Investigation
9 months ago
Healing the heart!
@eduardomarban.bsky.social
& team discover the long non-coding RNA BCYRN1 contained in extracellular vesicles from cardiosphere-derived cells modulates Tregs and reduces damage in a mouse heart-attack model:
buff.ly/n1q0Bac
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reposted by
Eduardo Marbán, MD, PhD
Journal of Clinical Investigation
9 months ago
Healing the heart!
@eduardomarban.bsky.social
& team discover the long non-coding RNA BCYRN1 contained in extracellular vesicles from cardiosphere-derived cells modulates Tregs and reduces damage in a mouse heart-attack model:
buff.ly/n1q0Bac
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Pleased to share our paper:
#EVs
released from
#heart
#postMI
travel to
#brain
and cause
#neuroinflammation
, underlying
#depression
. Work of Ke Liao, PhD
ahajournals.org/doi/epub/10.11…
9 months ago
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reposted by
Eduardo Marbán, MD, PhD
Russell Rogers, Ph.D.
9 months ago
Wonderful Research In Progress update by NIH T32 Fellow, Jonah Zarrow, on developing novel
#ncRNA
drugs for
#Duchenne
muscular dystrophy. Important work for
#DMD
!
@eduardomarban.bsky.social
@smidtheart.bsky.social
@mda.org
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reposted by
Eduardo Marbán, MD, PhD
Eugenio Cingolani, MD
9 months ago
Great
#Breakout
#Session
at Cedars Sinai Faculty Retreat
#NewTherapies
from
#Concept
to
#Clinic
Fantastic panel ➡️ Dr. Eduardo Marban
@eduardomarban.bsky.social
describing his pathway to
#clinic
#CDCs
followed by Dr. Anand Karumanchi going over his experiences towards
#translation
#regulatorypathways
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Brilliant
@smidtheart.bsky.social
research seminar by Rajan Sah MD PhD of Washington University on SWELL channels and their role in
#platelet
#thrombosis
. Big implications for therapeutics of
#MI
and
#stroke
.
#CardioSky
9 months ago
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Provocative
@smidtheart.bsky.social
#cardiology
grand rounds by Rita Redberg who highlights the low bar set for
@fda.gov
approval of medical devices. Hard clinical endpoints in adequately powered trials sorely lacking. No wonder investors prefer devices over drugs or novel biological therapies!
9 months ago
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Inspiring start to Cedars Sinai’s academic retreat by Shlomo Melmed, MD, who emphasizes how our unique structure enables progress towards science-based clinical innovation.
10 months ago
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New discoveries abound in
@ahmedgibrahim.bsky.social
as evidenced today by
#labmeeting
on
#EVs
and
#ncRNAs
from genetically engineered
#fibroblasts
that pulled a Jekyll and Hyde, becoming salutary post-
#MI
. Great work of Hiroaki Komuro!
#CardioSky
10 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
10 months ago
Let's get
#ACC25
started! ⬇️Check out the agenda and don't miss hearing from
@smidtheart.bsky.social
! Follow us all weekend for highlights!
@accintouch.bsky.social
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
10 months ago
Recent paper published in
@jclinical-invest.bsky.social
from
@eduardomarban.bsky.social
& Ke Liao finds a
#ncRNA
that enhances
#Treg
cells that could potentially repair heart muscle damage after a
#HeartAttack
& be applied to a variety of inflammatory disorders.
www.cedars-sinai.org/newsroom/pre...
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Preclinical Study: After Heart Attack, a Boost in Anti-Inflammatory Cells Promoted Healing
A scientific technique that rapidly increases the body’s production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Hea...
https://www.cedars-sinai.org/newsroom/preclinical-study-after-heart-attack-a-boost-in-anti-inflammatory-cells-promoted-healing/
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Check out the in-press preview of our @jclinicalinvest paper on regulatory
#Tcells
— we discovered a
#ncRNA
that can enhance
#Treg
dynamics fast enough to improve
#MI
healing in vivo. New hope for refractory inflammatory and immune conditions? 🔗
www.jci.org/articles/vie...
10 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
10 months ago
We’re ready for day 2 of the
#HFpEFSummit
listening in on sessions about exercise intolerance and the new and late breaking clinical trials! Exciting day ahead!
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@russellrogers.bsky.social
discussed experiments w/Lefer Lab taking advantage of the mechanistic differences between
#GLP1RA
&
#ncRNA
#TY1
as therapeutics for
#HFpEF
. Compelling evidence for synergistic benefits in two rodent models! Potential for less skeletal muscle loss?
@smidtheart.bsky.social
10 months ago
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The incomparable
@mkittlesonmd.bsky.social
teaches us that
#HFpEF
is a diagnosis of exclusion— rule out AS, HCM, pericardial constriction and, above all,
#amyloidosis
.
10 months ago
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reposted by
Eduardo Marbán, MD, PhD
Russell Rogers, Ph.D.
10 months ago
Pleased to share out latest work on cell therapy for
#Duchenne
. We show
#deramiocel
therapy initiated early protects against disease-related decline in muscle function.
@eduardomarban.bsky.social
@smidtheart.bsky.social
@stemcellreports.bsky.social
@mda.org
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Long-term preservation of muscle function and structure by repeated administration of cardiosphere-derived cells in mdx mice
Duchenne muscular dystrophy (DMD) is a progressive disease associated with functional decline. Chronic administration of cardiosphere-derived cell therapy prevents disease-related functional decline f...
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(25)00072-4
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Single nuclei
#RNAseq
of human
#HFpEF
heart biopsies by Virginia Hahn of
@hopkinsheart.bsky.social
reveals interesting
#macrophage
specific changes. Lots of provocative findings!
10 months ago
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Great opening lecture by
#HFpEF
pioneer
@dakheartguy.bsky.social
on
#sarcomere
abnormalities— huge differences in
#calcium
activated force in
#myocytes
from obese vs morbidly obese patients. Clinical correlation less evident…
@smidtheart.bsky.social
#CardioSky
10 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
10 months ago
The final agenda is up! We can't wait to see you tomorrow. Follow us Thursday and Friday for meeting highlights!
#HFpEF
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
We are less than 3 weeks away from the start of the
#HFpEF
Conference! There's still a few spots left, grab your seat now. Registration🔗
hfpefsummit.org
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
On
#RareDiseaseDay
, we honor the families who are fighting for a cure.
#DuchenneMD
, a disease that weakens muscles & affects the heart. Research led by
@eduardomarban.bsky.social
offers hope through
#CellTherapy
slowing
#HF
. This breakthrough may extend lives & change futures.
tiny.cc/8hob001
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Potential Treatment for Heart Disease Caused by Duchenne MD
Catherine Jayasuriya thought it was strange her then-6-year-old son, Dusty Brandom, seemed to fall down more often than other children and couldn’t keep up with his siblings. That year, 1998, Jayasuri...
https://www.cedars-sinai.org/newsroom/duchenne-heart/
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reposted by
Eduardo Marbán, MD, PhD
Barbra Streisand Women's Heart Center
11 months ago
Echoing this! 💙 A big THANK YOU to our fellows for your hard work and dedication—you make a difference every day!
#ThankAFellow
#HeartHeroes
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
👋 Say hi to our friends at
@womensheart.bsky.social
! Be sure to follow to keep up with the latest news from our Barbra Streisand Women's Heart Center. 🫶
#CardioSky
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Inspiring kickoff to
@fda.gov
Cell Therapy workshop with keynote lecture by Sally Temple— PSC-derived neural cells are coming into their own! FDA CBER has been highly supportive of this transformative field.
11 months ago
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@smidtheart.bsky.social
discoveries translated to the clinic….. Potential Treatment for Heart Disease Caused by Duchenne Muscular Dystrophy
www.cedars-sinai.org/newsroom/duc...
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Potential Treatment for Heart Disease Caused by Duchenne MD
Catherine Jayasuriya thought it was strange her then-6-year-old son, Dusty Brandom, seemed to fall down more often than other children and couldn’t keep up with his siblings. That year, 1998, Jayasuri...
https://www.cedars-sinai.org/newsroom/duchenne-heart/
11 months ago
0
2
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Terrific editorial by Noel Bairey Merz, Holly Andersen and
@drmarthagulati.bsky.social
lamenting the dire consequences of federal funding cuts for women's heart health-- will 4 decades of progress be undone?
@womensheart.bsky.social
@smidtheart.bsky.social
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11 months ago
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In an effort to pretend life is normal and we can just talk science, our
#journalclub
today featured Liz on the lasting epigenomic traces of
#obesity
; Diana on ML-directed
#protein
#evolution
; and James critiqued
#iPSC
#cardiomyocyte
sheets. A welcome distraction from the prevailing woes about NIH.
11 months ago
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On Feb 25,
@fda.gov
is proceeding with its scheduled workshop on
#celltherapy
. The agenda starts with an address by CBER Director Peter Marks, WarpSpeed hero, and is packed thereafter. Tune in for my session at 230PM EST. 🔗
www.fda.gov/news-events/...
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Cell Therapies and Tissue-Based Products: A Public Workshop on Generat
CBER, OTP is hosting a virtual scientific public workshop on February 25, 2025, titled “Cell Therapies and Tissue-based Products: A Public Workshop on Generating Scientific Evidence to Facilitate Deve...
https://www.fda.gov/news-events/otp-events-meetings-and-workshops/cell-therapies-and-tissue-based-products-public-workshop-generating-scientific-evidence-facilitate
11 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
We're proud to share with the community the
@smidtheart.bsky.social
Institute's 2025 Quarterly Report. 🔗
www.cedars-sinai.edu/health-scien...
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Great plenary talk by Jennifer Van Eyk at Cardiac Muscle Society meeting on
#proteomics
of the 🫀— inspiring journey of discovery from 2d gels of tissue to single-cardiomyocyte protein profiling!
11 months ago
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8
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Exciting new findings on
#SAnode
dysfunction in
#HFpEF
by Thassio Mesquita in our
#labmeeting
today. Chronotropic incompetence is due to intrinsic
#pacemaker
abnormalities!
#CardioSky
11 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
We're counting down to the HFpEF Summit! 🗓️March 19-21 🏨Beverly Hills, CA Looking forward to hearing from a great line up of internationally recognized leaders in the clinical, biological, and translational study of
#HFpEF
. See you there! 🔗
hfpefsummit.org
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
We wear red to raise awareness about heart disease in women. Let’s stand together to spread the message of heart health, prevention, and action. ❤️
#WearRedDay
#GoRedForWomen
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reposted by
Eduardo Marbán, MD, PhD
Jeanna Huynh
11 months ago
Our labs got our red on!
@russellrogers.bsky.social
@ahmedgibrahim.bsky.social
@eduardomarban.bsky.social
#WearRedDay
#GoRedForWomen
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
11 months ago
Don’t forget it’s Wear Red Day! Join us in wearing red today to raise awareness for women's heart health! Together, we can spread knowledge, inspire action, and empower women to take charge of their heart health. Share with us your red outfit of the day!
#WearRedDay
#GoRedForWomen
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A great pleasure to host my former
#postdoc
@stevenpjones.bsky.social
of the
@cardiometabosci.bsky.social
@uoflenvirome.bsky.social
as Visiting Professor in our
@smidtheart.bsky.social
#Frontiers
seminar series. The intersection of
#metabolism
and
#inflammation
is vital!
12 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
12 months ago
February is American Heart Month! Let's unite and wear red on Friday Feb 7 to support women's heart health. Let's spread awareness, encourage healthy habits, and take care of our hearts! ❤️
#HeartHealth
#WearRed
#GoRedForWomen
#cardiosky
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
12 months ago
Day 2 of Controversies is on the way with discussions on
#EP
#Imaging
#CAD
#AI
#HeartFailure
#INOCA
See you soon!
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Stimulating discussion of best therapy for
#bicuspid
#aortic
#stenosis
by, among others, Aakriti Gupta and Michael Bowdish. Paradoxical realization that bioprosthetic valves may be worse than mechanical ones in young people…. Let alone
#TAVR
vs
#SAVR
.
12 months ago
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5
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Provocative summary of
#AI
in
#medicine
by Sumeet Chugh.
#CardioSky
@smidtheart.bsky.social
12 months ago
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1
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
12 months ago
Controversies afternoon keynote lecture delivered by
@eduardomarban.bsky.social
discussing the development of a new
#ncRNA
drug to treat
#Scleroderma/#SystemicSclerosis
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Great talk on
#Lpa
by
@drmarthagulati.bsky.social
in
@smidtheart.bsky.social
outstanding
#Controversies
meeting!
12 months ago
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
12 months ago
Study from J. VanEyk's lab showed the significant
#therapeutic
potential of PR-364 for the prevention of
#HeartFailure
progression & in cardiac protection for patients after experiencing a
#HeartAttack
.
#CardioSky
cedars-sinai.org/newsroom/dru...
@eduardomarban.bsky.social
@escardio.bsky.social
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Drug Prevents Heart Failure After Heart Attacks in Mice, Study Finds
A specially designed drug prevented laboratory mice from developing heart failure after heart attacks, according to new research from Cedars-Sinai. This discovery could lead to new treatments to preve...
https://cedars-sinai.org/newsroom/drug-prevents-heart-failure-after-heart-attacks-in-mice-study-finds/
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reposted by
Eduardo Marbán, MD, PhD
Smidt Heart Institute
12 months ago
There’s still time to register for Controversies! Can’t wait to see everyone on Thursday!
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