Cosmin Tudose
@cosmintudose.bsky.social
📤 45
📥 77
📝 17
Postdoctoral researcher @IBCII Perturbation Genomics Lab Omics | Bioinformatics | Cancer
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Pleased that the 2nd part of my PhD is now available as a preprint! Here, we investigated the epigenomic and transcriptomic changes occurring upon PRC2 depletion in AML cells.
biorxiv.org/content/10.1...
. A thread🧵1/17
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Diverse epigenomic mechanisms underpin transcriptional dysregulation in Polycomb-altered acute myeloid leukemia
Background Polycomb Repressive Complex 2 (PRC2) modulates chromatin accessibility and architecture to direct tissue-specific gene expression. PRC2 function is frequently altered in cancer by loss-of-f...
https://biorxiv.org/content/10.1101/2025.08.28.672871v1
21 days ago
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Pleased that the 2nd part of my PhD is now available as a preprint! Here, we investigated the epigenomic and transcriptomic changes occurring upon PRC2 depletion in AML cells.
biorxiv.org/content/10.1...
. A thread🧵1/17
loading . . .
Diverse epigenomic mechanisms underpin transcriptional dysregulation in Polycomb-altered acute myeloid leukemia
Background Polycomb Repressive Complex 2 (PRC2) modulates chromatin accessibility and architecture to direct tissue-specific gene expression. PRC2 function is frequently altered in cancer by loss-of-f...
https://biorxiv.org/content/10.1101/2025.08.28.672871v1
21 days ago
1
4
3
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