Super excited and thrilled to see this work come out in Nature today. 🥹@tdcapellini.bsky.social Thank you so much for your amazing mentorship throughout the project, and to all my co-authors who helped take this work to the next level.

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...

New paper today about the evolution of the wrist along the dinosaur to bird transition: a bird-like configuration appeared in predatory dinosaurs first, as suggested by new exceptionally preserved hands of oviraptors and troodontids www.nature.com/articles/s41...

Thrilled to have co-written a News & Views with P. Janvier on Haridy et al.’s recent Nature paper. They reveal that Anatolepis, once thought to have the oldest dental tissue, is actually Cambrian arthropod sensory armor! Paper: nature.com/articles/s41... N&V: www.nature.com/articles/d41...

Glad to share a new paper led by @yara_haridy and @NeilShubin Lab on the early evolution of teeth! Modern and fossil data point at an ancestrally sensorial function for the earliest dentine www.nature.com/articles/s41...

Glad to see the formal description of the Chicago specimen of #Archaeopteryx finally out in @nature.com! Troodontid and early bird features in the palate and evidence of tertiary feathers www.nature.com/articles/s41...

Super excited to share our @plosbiology.org paper with @neilshubin.bsky.social and Yara Haridy, “Synovial joints were present in the common ancestor of jawed fish but lacking in jawless fish” Paper: plos.io/3CTC8La Primer by @crumplab.bsky.social: plos.io/4kkhXa6 I hope you enjoy reading it!

When did synovial joints evolve? @neelimasharma.bsky.social @neilshubin.bsky.social &co reveal that stable, mobile & lubricated joints were present in the common ancestor of jawed fishes but lacking in jawless ones 🧪 @plosbiology.org plos.io/3CTC8La

New paper led by @neelimasharma.bsky.social on the lab! The evolutionary origin of highly mobile joints!

@philipcball.bsky.social gets a bit spicier in places than I did, "it can be hard to avoid the suspicion that sometimes its (omics data) collection serves to postpone the awkward time when some sense must be made of it all." And I like it :)

With gratitude to the Keck Foundation, we get to work on a project with Dana Rashid (MSU) and Susan Chapman (Clemson U) that was inspired by Dana's studies of the dino-bird transition. today.ucsd.edu/story/uc-san...

Ever wondered how your #genes know when to turn on or off? 🧬🔌 In our latest #BioBasics episode, @juliannahaug.bsky.social, a researcher in the Sauka-Spengler Lab, explains gene regulatory networks — the circuits that control gene activity. Watch + learn more: bit.ly/4jYJmxR

Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.

"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

CellOracle In silico transcription factor KO via cell type-specific Gene-Regulatory Network modeling #Nature 2023 www.nature.com/articles/s41...

royalsocietypublishing.org/doi/10.1098/... This looks right up my street, can't wait to read!

NSF has created an Executive Order Implementation webpage to ensure the widest dissemination of information and updates. We will continue to communicate with you as we receive additional guidance. new.nsf.gov/executive-or...

We are excited to share our work on molar #evodevo 🦷 in mouse and hamster 🐁, led by the amazing team of Marie Sémon and Sophie Pantalacci. We find an inverted hourglass pattern, with a maximum of evolutionary divergence at the bell stage. https://www.biorxiv.org/content/10.1101/2025.01.23.634446v1

Latest from the lab! I've been seeking the ultimate modulator that regulates the tempo of multiple developmental processes simultaneously, and metabolism has been an attractive candidate for such a global tempo modulator. However, I was wrong. 1/ www.nature.com/articles/s41...

Happy #FluorescenceFriday to those who celebrate! Here's a beautiful quail neural tube and somites labelled for microtubules 🟠 and actin 🔵. Imaged by Power-RA Siew Zhuan Tan. #devbio 🧪🔬👩‍🔬

Postdoc in @planaria1.bsky.social Lab, @rileynoceros.bsky.social, joins the 2024 class of @hhmi.bsky.social #HannaGrayFellows! Her work on how some vertebrates “pause” their development could transform our understanding of #evolution & human #medicine – listen as she explains: bit.ly/4g8xWED

I am very proud of the work that went into this new Sanger Lab publication. This paper was led by postdoc Marta Marchini and a number of my lab's undergraduate students, each of which contributed unique skills or effort to the completion of this project.

Pretty neat story here by Marta Marchini, @thomsanger.bsky.social and coauthors. Our first look at the role of FGF and HH signaling in the lizard face (Anolis), with big implications for the ancestral amniote condition 1/n www.nature.com/articles/s42...

Dear #neuralcrest afficionados Please Apply for the Neural Crest and Cranial Placodes GRC - the current application numbers put it at risk for cancellation going forward. Come to beautiful Tuscany and engage with interesting science! www.grc.org/neural-crest...

Great to see old pals and new results at #SICB2025, including Yara Haridy's deep dive into some of the earliest bony skeletons: www.science.org/content/arti...

🚨New Diamond 💎 Open Access Journal in Paleontology 🦴🐚!🚨 Send us your manuscripts 📜 and publish fully open access 🔓 entirely for free! #openacess #paleontology #free #palaeontology #diamond #open

Eventually, we studied development of sticky toes! We found similar derived developmental patterns of convergently evolved #toepads, despite approximately 200 million years of independent evolution! @tonygamble.bsky.social @thomsanger.bsky.social #GeckoEvoDevo academic.oup.com/biolinnean/a...

I have a new paper out on the evolution of hearing in toothed whales! It looks like a narrow range of high-frequency auditory sensitivity in some living dolphins and porpoises may be an ancestral physiology rather than novel specializations in select groups. onlinelibrary.wiley.com/doi/10.1111/...

TRISCO A solid step closer to 3D #SpatialTranscriptomics 😎 Optimized probe-based 3D RNA imaging in whole organs isHCR Tris 500 mM 4'C Validated probe list in Table S1 Brain Heart Lung Kidney @peruhlen.bsky.social @science.org 2024 www.science.org/doi/10.1126/...

Your reminder that many of the muscles, nerves and bones you use to hear and talk with correspond to gill structures in fish. 🧪 #evolution #paleontology

New paper! For all of you working with 3d scans (e.g. micro-CT, MRI), check out SPROUT, a rapid open-source tool for generating segmented and parcellated data, meaning your scans are separated into the individual elements without any manual labelling or training. www.biorxiv.org/content/10.1...

Considering that turkey day is approaching, enjoy a close up of its origins for #fossilfriday. The Chicago specimen of #Archaeopteryx

Picture of history being made

Excited to share work that @ceriweber.bsky.social started and drove in my lab. Tails!! We know a lot about limb bone growth, but vertebrae have completely different embryonic and evolutionary origins. What controls growth and proportion in the vertebral skeleton? www.biorxiv.org/content/10.1...

Thrilled to share: out in @natureportfolio.bsky.social (!) just in time for Thanksgiving, the dinosaurian history of how your turkey does the twist. Fibular reduction enabled mid-drumstick mobility, unlocking extreme knee long-axis rotation in theropods 🍗🦖🧵 www.nature.com/articles/s41586-024-08251-w