Muriel Perron
@murielperron.bsky.social
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CNRS researcher interested in neural stem cells, retina, and regeneration
reposted by
Muriel Perron
Seth Blackshaw
25 days ago
Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1
www.biorxiv.org/content/10.1...
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Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging.
Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...
https://www.biorxiv.org/content/10.1101/2025.09.09.673285v1
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reposted by
Muriel Perron
Juliane Glaser
about 1 month ago
🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development. We will have positions available next year. Stay tuned!
add a skeleton here at some point
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Muriel Perron
Kara Cerveny
about 1 month ago
Come be my colleague! We are hiring for two tenure-track positions.
www.reed.edu/dean_of_facu...
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Tenure-Track Positions in Functional Genomics/Genetics and Systems Biology - Office of the Dean of the Faculty - Reed College
https://www.reed.edu/dean_of_faculty/facsearch/positions/tenure-track-positions-in-functional-genomicsgenetics-and-systems-biology.html
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Muriel Perron
Developmental Biology
about 2 months ago
Early embryonic developmental pathways are activated during regeneration phase in Xenopus 🐸 --by Aniket Kshirsagar, Rachel Ronan, Ana Lúcia Rebelo, Siobhan McMahon, Abhay Pandit, and Gerhard Schlosser
www.sciencedirect.com/science/arti...
#Xenopus
#regeneration
#DBfeature
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reposted by
Muriel Perron
Justin Kumar
2 months ago
My lab's newest research paper on the Drosophila eye is published in Development today. Thanks to the editorial staff for writing a research highlight and interviewing us about our work.
journals.biologists.com/dev/article-...
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Differential regulation of eye specification in Drosophila by Polycomb Group epigenetic repressors
Highlighted Article: Distinct gene sets are differentially expressed in response to the knockdown of Polycomb Group (PcG) members, suggesting that multiple avenues may exist for the eye to be transfor...
https://journals.biologists.com/dev/article-abstract/152/14/dev204317/368723/Differential-regulation-of-eye-specification-in
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Deadline approaching: 22 Aug 2025!!! Tenure-track Junior Professor (CPJ) in Multi-omics Cell Atlases of Brain Development
@neuropsi.bsky.social
@univparissaclay.bsky.social
Details:
www.universite-paris-saclay.fr/sites/defaul...
Apply via ODYSSEE:
odyssee.enseignementsup-recherche.gouv.fr
2 months ago
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Muriel Perron
Paris-Saclay Institute of Neuroscience
3 months ago
🔬🐁 We have a new position open! ➡️ Our "Chaire Professeur Junior" position focuses on multi-omics during brain development. This research-heavy position follows a tenure-track scheme, leading to a full professor position. 🗓️ Application deadline: 22/08/2025
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https://www.universite-paris-saclay.fr/sites/default/files/2025-06/Sciences%20Atlas_Offre253101.pdf
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reposted by
Muriel Perron
Paris-Saclay Institute of Neuroscience
5 months ago
A tenure track "AI and pathological behavioral trajectories" Professor position is open at NeuroPSI. Learn more and apply 🔽🔽🔽🔽🔽🔽
emploi.cnrs.fr/Offres/CPJ/C...
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Muriel Perron
Paris-Saclay Institute of Neuroscience
5 months ago
Join us next Monday and Tuesday (May the 19-20) for the 2025 joint TCCI/NeuroPSI conference! This year the conference focuses on Social cognition, Decision making & Communication. You can still register to attend online: neuropsi-2025.sciencesconf.org
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Muriel Perron
Xenbase
5 months ago
Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions.
www.xenbase.org/xenbase/doNe...
#science
#devbio
#xenopus
#frogs
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A Tenure-track Junior Professor Chair (CPJ) is now open at
@neuropsi.bsky.social
Focus: Multi-omics cellular atlases of brain development Application details & deadline coming soon, stay tuned!
@univparissaclay.bsky.social
5 months ago
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Muriel Perron
Seth Blackshaw
5 months ago
The final version of our eLife manuscript on viral Oct4-mediated neurogenic reprogramming of retinal Muller glia is now out, with all reviewer comments addressed.
elifesciences.org/reviewed-pre...
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Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
https://elifesciences.org/reviewed-preprints/106450#tab-content
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reposted by
Muriel Perron
Seth Blackshaw
5 months ago
Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...
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Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...
https://www.biorxiv.org/content/10.1101/2025.04.25.650540v1
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reposted by
Muriel Perron
Seth Blackshaw
6 months ago
Our latest manuscript on glia-to-neuron conversion in retina is out in
@elife.bsky.social
. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj.
elifesciences.org/reviewed-pre...
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Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
https://elifesciences.org/reviewed-preprints/106450#tab-content
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The Paris-Saclay Institute of Neuroscience
@neuropsi.bsky.social
has launched a call for new group leaders. Please spread the word! deadline May 30
neuropsi.cnrs.fr/wp-content/u...
@cnrs.fr
@univparissaclay.bsky.social
7 months ago
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reposted by
Muriel Perron
Paris-Saclay Institute of Neuroscience
8 months ago
Le programme de la semaine du cerveau se précise. Toute la semaine du 10 mars, NeuroPSI et NeuroSPIN vous accueillent à tour de rôle pour une série de conférences et d'animation à destination de tous les publics !
neuropsi.cnrs.fr/semaine-cerv...
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Muriel Perron
Paris-Saclay Institute of Neuroscience
7 months ago
▶️ The 2025 TCCI-NeuroPSI conference will take place on May 19-20 at NeuroPSI. ▶️ Dive with us into the dynamic interactions between social cognition, emotions and communication systems, which enable adaptive choices in complex social environments! ▶️ Register: neuropsi-2025.sciencesconf.org
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reposted by
Muriel Perron
Seth Blackshaw
7 months ago
Our new review article with
@michelcayouette.bsky.social
is out on temporal patterning and glial reprogramming in adult CNS, and its implications for treating degenerative diseases. All work from our lab discussed here was funded by NIH.
authors.elsevier.com/a/1kfup3Q9h2...
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https://authors.elsevier.com/a/1kfup3Q9h2MGoE
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reposted by
Muriel Perron
Michel Cayouette
7 months ago
Happy to share this review that
@sethblackshaw.bsky.social
and I wrote about temporal patterning and how these mechanisms could be coaxed to stimulate glia reprogramming and CNS regeneration! Access link below, feel free to use the figures in your talks!😊
authors.elsevier.com/c/1kfup3Q9h2...
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https://authors.elsevier.com/c/1kfup3Q9h2MGoE
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reposted by
Muriel Perron
Ryan MacDonald
8 months ago
We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model.
www.ucl.ac.uk/work-at-ucl/...
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UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?jobId=31843&jobTitle=Research+Fellow
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reposted by
Muriel Perron
Seth Blackshaw
8 months ago
Introducing MetaLigand, our latest collaboration with the Qian group, a database for predicting non-peptide ligand mediated cell-cell signaling.
www.biorxiv.org/content/10.1...
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MetaLigand: A database for predicting non-peptide ligand mediated cell-cell communication
Non-peptide ligands (NPLs), including lipids, amino acids, carbohydrates, and non-peptide neurotransmitters and hormones, play a critical role in ligand-receptor-mediated cell-cell communication, driv...
https://www.biorxiv.org/content/10.1101/2025.01.14.633094v1
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The correct version of our paper in ScienceAdvances is now live on PubMed! (Yes, our entire Figure 3 had been mysteriously swapped… but it's all fixed now!) It is about the complex role of inflammation in Müller glia response to injury.
science.org/doi/10.1126/...
@neuropsi.bsky.social
8 months ago
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reposted by
Muriel Perron
Paris-Saclay Institute of Neuroscience
9 months ago
🐁 Découvrez notre animalerie et certaines des recherches qui y sont menées dans cette nouvelle video de la série "Les visites du GIRCOR"!
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"À la découverte de nos différences grâce aux souris" - Les visites du Gircor
YouTube video by Gircor
https://youtu.be/BqmAiL1rryk
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Muriel Perron
Paris-Saclay Institute of Neuroscience
9 months ago
🗓️ La prochaine Semaine du Cerveau c'est du 10 au 14 mars prochain. 🧠Rejoignez-nous à NeuroPSI, en partenariat avec Neurospin et
@cea-joliot.bsky.social
, pour de nombreuses conférences et animations! Suivez-nous ici pour en savoir bientôt davantage...
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Semaine du Cerveau 2025 - Institut des Neurosciences Paris‑Saclay
La Semaine du cerveau 2025 est organisée conjointement par NeuroSpin (Institut Joliot) et par l'Institut NeuroPSI. Programme prévisionnel du 10 au 14 mars 2025 Pour la deuxième année consécutive, la...
https://neuropsi.cnrs.fr/semaine-cerveau-2025/
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Muriel Perron
Paris-Saclay Institute of Neuroscience
8 months ago
🗓️ On the 19th and 20th of May 2025, we will host the 3rd edition of the joint TCCI - NeuroPSI international conference. ▶️ This year topic will be Social cognition, Decision making & Communication. ▶️ Stay tuned for our speakers list, registration and more!
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reposted by
Muriel Perron
Paris-Saclay Institute of Neuroscience
9 months ago
We are pleased to announce a Youtube channel for our institute:
www.youtube.com/@NeuroPSI-sa...
You will find here a selection of our conferences, and more!
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NeuroPSI
https://www.youtube.com/@NeuroPSI-saclay
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reposted by
Muriel Perron
Seth Blackshaw
9 months ago
We begin the New Year with two preprints on hypothalamic development. The first, part of a long-term collaboration with Marysia Placzek’s group, investigates the organization of the developing forebrain, and show that current models are (mostly) incorrect./1
www.biorxiv.org/content/10.1...
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Resolving forebrain developmental organisation by analysis of differential growth patterns
The forebrain is the most complex region of the vertebrate CNS, and its developmental organisation is controversial. We fate-mapped the embryonic chick forebrain using lipophilic dyes and Cre-recombin...
https://www.biorxiv.org/content/10.1101/2025.01.10.632351v1
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reposted by
Muriel Perron
Seth Blackshaw
9 months ago
Our second preprint, which was spearheaded by
@thomasdwkim.bsky.social
, uses single-cell multiomic analysis to identify gene regulatory networks controlling neurogenesis and cell fate specification in mouse hypothalamus and prethalamus./1
biorxiv.org/cgi/content/...
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reposted by
Muriel Perron
11 months ago
Thrilled to announce that our lab is relocating to the Friedrich Miescher Laboratory of the Max Planck Society
@mpi-bio-fml.bsky.social
in winter 2025. We’ll have open positions— please help us spread the word and stay tuned for more updates! 🐸 🐁 🥳
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Muriel Perron
Frog Wranglers
10 months ago
We’re thankful for cool new AAV tools in
#xenopus
!
pubmed.ncbi.nlm.nih.gov/39603234/
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reposted by
Muriel Perron
Webvision
11 months ago
Check out a virtual symposium on Astrocytes, Microglia and Neuroinflammation in the eye from Harvard's Dept. of Ophthalmology and Mass Eye and Ear on Dec. 5th and 6th. Check out deets below.
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reposted by
Muriel Perron
Michel Cayouette
11 months ago
Our latest work is out!! Short thread below.
www.cell.com/developmenta...
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Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina
Housset et al. show that basal bodies of cone photoreceptors in the mouse retina are planar polarized in a light-dependent manner by the action of transducin and G-protein-signaling modulator protein ...
https://www.cell.com/developmental-cell/abstract/S1534-5807(24)00631-2
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Muriel Perron
Altmetric
11 months ago
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky
#HigherEd
#Altmetrics
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Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
https://docs.bsky.app/docs/advanced-guides/intent-links
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Muriel Perron
Levi Todd
11 months ago
First paper from our lab officially out. And they let us put Muller glia, the indisputably most interesting cell in the body on the cover.
www.jneurosci.org/content/44/4...
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Muriel Perron
James Briscoe
11 months ago
Upcoming Development Special Issue 'Lifelong Development' Beyond the embryo: tissue maintenance, regeneration & plasticity Guest eds: Meri Huch & Mansi Srivastava Deadline: 15 May 2025 All article types welcome
#DevBio
#Regeneration
#StemCells
journals.biologists.com/dev/pages/li...
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CFP | Lifelong Development | Development | The Company of Biologists
CFP | Lifelong Development | Development | The Company of Biologists Special Issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Development invites yo...
https://journals.biologists.com/dev/pages/lifelongdev
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Muriel Perron
Alex Eve
11 months ago
Developmental processes don't just occur in the embryo! Development's (
@biologists.bsky.social
) next Special Issue - Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues. Papers: 15 May 2025.
#devbio
#regeneration
#stemcells
journals.biologists.com/dev/pages/li...
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CFP | Lifelong Development | Development | The Company of Biologists
CFP | Lifelong Development | Development | The Company of Biologists Special Issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Development invites yo...
https://journals.biologists.com/dev/pages/lifelongdev
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Muriel Perron
Antoine Zalc
11 months ago
🚨🚨🚨 Call is now open!!! Wanna become our new beloved colleague and be part of a stimulating (and friendly) scientific community ??? We are perfectly located in beautiful Paris with exciting work environment and state-of-the-art core facilities APPLY 👇👇👇👇👇
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Why did I wait so long to come here??? It was so easy! Excited to see you all on Bluesky!
11 months ago
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