Nature research paper: Humoral determinants of checkpoint immunotherapy go.nature.com/41a8fin

Congratulations 👏👏 Ngoc and @elizabetharkema.bsky.social ! These data are important in helping us to select the most suitable immunosuppressant during pregnancy. #Medsky Looking forward to future collaborations 🙂 🇸🇪🇺🇸🇻🇳🇫🇷 !

Two patients with monoclonal anti-PF4 antibodies, thrombosis, and chronic thrombocytopenia also had first-trimester pregnancy losses, findings that suggest a possible link between these antibodies and obstetrical complications. Read the full report: nej.md/4luAlx1 #MedSky #OBGYN

Congratulations 👏👏 to @mimrobert.bsky.social for this very nice work 🗞 It seems worthy to look at anti-13 antibody during the follow-up of #iTTP . Maybe to guide anti-CD20 therapy ? #Medsky @amjh.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

🌞 Un air d’été à l’hôpital Bichat – Claude-Bernard @ap-hp.bsky.social ! Ce midi, l’hôpital a célébré l’arrivée de l’été avec un déjeuner estival en musique, au jardin de la crèche du secteur Claude-Bernard 🎶🍔🌿

BCMA CAR T therapy to treat autoimmune cytopenias resistant to CD19 CAR T...🤯 Sounds like sci-fi but it is already there in @nejm.org ! Is this really the future of clinical immunology ? Let's wait and find out !

Betw 2005 -2021, there was a substantial increase in HCQ use, but only modest steroid (GC) reductions. Swedish cohort study of 3891 SLE pts - over 5 yrs GC decr from 68% - 54% to 46%. HCQ increased by 29% over 5 years. buff.ly/7HudhKH

Looking for subliclinical atherosclerosis with vascular ultrasound could help us stratify the cardiovascular🩺 risk in #SLE #MedSky @lupusjournal 🗞 @hopitalbichat.bsky.social 🏥 doi.org/10.1177/0961...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. Learn more in a new review: nej.md/42gEZYk #MedSky #GastroSky

Human papillomavirus et lupus systémique : une revue systématique www.sciencedirect.com/science/arti... #SLE #HPV

An interesting design to test the prophylactic efficacy of 💊trimethoprin - sulfamethoxazole in #AAV #Medsky acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Congratulations 👏👏 to @AnnicaDominicus and @elizabetharkema.bsky.social for this useful work about temporal trends📉 in GC and HCQ for treatment of #SLE 🦋. Are our practices in line with the evolution of treatment recommendations? Let's find out : doi.org/10.1093/rheu...

We need safety 🦺 data regarding elderly patients with #GCA but this looks very interesting : @nejm.org #Medsky A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis | New England Journal of Medicine www.nejm.org/doi/full/10....

Absolute iron deficiency affects approximately 2 billion people worldwide. This narrative review examines the screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia. #ACC25 https://ja.ma/3Xw1i9K

Treating polymyalgia rheumatica with baracitinib but without oral glucocorticoids ? #MedSky Interesting 🇫🇷 findings 🗞 @thelancetrheum.bsky.social www.thelancet.com/journals/lan...

J&J announced the FDA jas granted the investigational drug, nipocalimab (FcRn recpt Ab), with Fast Track designation for its study in adult patients with moderate-to-severe Sjögren’s disease buff.ly/SFYky98

Does tolerance for uncertainty 🤷 affect medical students' specialty choice ? #Medsky @medicaleducation.bsky.social I used to think that internal medicine or emergency medicine physicians had a better tolerance than others... asmepublications.onlinelibrary.wiley.com/doi/10.1111/...

An old new immunosuppressant 💊 for lupus nephritis ? Mizoribine vs CYC in this original study #MedSky @jama.com . In the era of Mabs, it is quite unexpected ! jamanetwork.com/journals/jam...

Rare PROS1 variants significantly increase venous thromboembolism risk, revealing low protein S as a key factor in thrombotic disorders. by Chaudhry SA, Haj AK (...) Bendapudi PK et 9 al. in JAMA #MedSky 📖 read the article:

Could we use serum type I interferon score for prediction of disease progression in limited cutaneous systemic sclerosis ? Retrospective data look convincing enven if they need to be reproduced in a different setting. #Medsky 📰: acrjournals.onlinelibrary.wiley.com/share/UNQCUF...

What are the clinical presentation and outcomes of adult patients with immune mediated inflammatory disease who were hospitalised following an ED referral 🚑 ? Find out in this study from @ElisaChapuis 👏 #MedSky @hopitalbichat.bsky.social rdcu.be/eb54T

"L’Ordre des médecins, mis en cause pour son attitude face au chirurgien pédocriminel Joël Le Scouarnec, est chargé d’assurer la discipline dans la profession médicale. Il est régulièrement accusé d’avoir une approche corporatiste et conservatrice." www.lanouvellerepublique.fr/a-la-une/l-o...

Some interesting and original insights into the complex relationship between EBV 🦠 and autoimmunity 😷 ard.bmj.com/content/earl...

Another disappointment for the use of microbiota tansplantation in autoimmune disease, here in #SSc @thelancet.bsky.social Will it have any indication in clinical practice ? #MedSky www.thelancet.com/journals/lan...

Pas une ride

Interesting Swedish data #ki about the assocation of infection burden with Kawasaki dz. "Differents agents may induce the disease" authors say. 🗞 It would be so interesting to understand the immune mechanisms behind this non-specific post-infection autoimmunity. rmdopen.bmj.com/content/11/1...

Journal of Human Immunity (JHI) @jhumimmunity.org is here! Read the inaugural editorial by @casanovalab.bsky.social outlining #JHI’s vision as the destination for groundbreaking research in human immunity and inborn errors of immunity. https://buff.ly/4hRGpOb #OpenAccess

Encore une bonne raison de dissoudre l'ordre des médecins ! Comment peut-on encore supporter cette institution inutile et défaillante ? www.lemonde.fr/societe/arti...

Les CAR T allogéniques commencent à montrer des résultats intéressants dans le traitement des DLBCL: ascopubs.org/doi/10.1200/... Il y aura-t-il bientôt une place pour ces traitements en immuno clinique ? Quel avantage par rapport au CAR T autologues dans ces situations ?

Monoclonal gammopathy of thrombotic significance ! Un de plus dans la collec' www.nejm.org/doi/10.1056/...