Colin Nichols Lab (@colinnicholslab.bsky.social)

Check out our new publication "Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels" 🧪 diabetesjournals.org/diabetes/art... @rosca26.bsky.social A 🧵 1/n

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Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels Pancreatic β-cell ATP-sensitive K+ (KATP) channel closure underlies electrical excitability and insulin release, but loss or inhibition of KATP channels ca https://diabetesjournals.org/diabetes/article/doi/10.2337/db25-0110/158201/Paradoxical-Maturity-Onset-Diabetes-of-the-Young