Sam Bloom
@sambloom28.bsky.social
📤 93
📥 244
📝 0
Postdoc in the
@karlsederlab.bsky.social
at The Salk Institute for Biological Studies
reposted by
Sam Bloom
Metztli Cisneros-Aguirre
3 months ago
🧬Register for the GRS on DNA Damage, Mutation & Cancer🧬 Feb 28–Mar 1 2026, Ventura CA Accepting abstracts for oral presentations! 
📍 Apply here 👉
grc.org/dna-damage-mutation-and-cancer-grs-conference/2026
(
www.grc.org/dna-damage-m...
)
#DNADamage
#GRC#GRS
#CallForAbstracts
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2026 DNA Damage, Mutation and Cancer (GRS) Seminar GRC
The 2026 Gordon Research Seminar on DNA Damage, Mutation and Cancer (GRS) will be held in Ventura, California. Apply today to reserve your spot.
https://grc.org/dna-damage-mutation-and-cancer-grs-conference/2026
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reposted by
Sam Bloom
JStark lab
3 months ago
📢📢Apply now for GRS/GRC on DNA Damage Mutation & Cancer in sunny Ventura CA.
add a skeleton here at some point
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reposted by
Sam Bloom
Joe Nassour
6 months ago
Out now in CSH Perspectives in Biology (Telomeres & Telomerase) : “Telomere crisis shapes cancer evolution.”
cshperspectives.cshlp.org/content/earl...
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reposted by
Sam Bloom
Genes & Development
5 months ago
SYMPOSIUM OUTLOOK:
#Telomeres
at the nexus of
#aging
,
#tumor
suppression, and
#inflammation
: toward an understanding beyond
#senescence
By Samuel Bloom & Jan Karlseder ➡️ https://bit.ly/410dJwg
##cshlsymp25
#DNAdamage
#replicativesenescence
#DNAreplication
#crisis
#cancer
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reposted by
Sam Bloom
Karlseder Lab
6 months ago
Our lab’s latest “hot take” is out in Genes & Development! We argue for looking beyond senescence to understand how telomeres connect aging, tumor suppression, and inflammation. Great job
@sambloom28.bsky.social
! 👉 DOI: 10.1101/gad.353122.125
genesdev.cshlp.org/content/earl...
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Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
https://genesdev.cshlp.org/content/early/2025/07/11/gad.353122.125
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reposted by
Sam Bloom
Joe Nassour
9 months ago
New preprint out! We propose a “degradative flux” mechanism for tonic STING signaling in ALT+ cells, driven by IRF3-dependent trafficking and clearance of immunogenic extrachromosomal telomeric repeats—a process that could be targeted for cancer immunotherapy
www.biorxiv.org/content/10.1...
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https://www.biorxiv.org/content/10.1101/2025.04.18.649516v1
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reposted by
Sam Bloom
Dawid Zyla
12 months ago
I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out:
mssearch.xyz
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Streamlit
https://mssearch.xyz/
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reposted by
Sam Bloom
Karlseder Lab
12 months ago
Huge thanks to Hannah Trost, Gabriel Matos Rodriguez, Roger Greenberg, and Hilda Pickett for an amazing Mammalian DNA Repair GRS/GRC in Ventura! Already excited for the next one!
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reposted by
Sam Bloom
Karlseder Lab
about 1 year ago
With our lab’s inaugural Blue Sky post we celebrate our latest publication, a review in Nature Reviews Molecular Cell Biology (
@natrevmcb.bsky.social
) 🥳 Here, we review our current understanding of telomere biology, discussing differences between human and mouse.
www.nature.com/articles/s41...
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Telomere function and regulation from mouse models to human ageing and disease - Nature Reviews Molecular Cell Biology
Telomere dysfunction, usually owing to shortening, activates cellular senescence and can contribute to age-associated diseases and cancer. Mouse models are crucial for telomere research, but human and...
https://www.nature.com/articles/s41580-024-00800-5
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