Jake Smith
@cryingem.bsky.social
π€ 585
π₯ 383
π 18
reposted by
Jake Smith
Alice Auersperg
22 days ago
Our new paper (with
@biotay.bsky.social
) is out and on the cover story of
@currentbiology.bsky.social
!!!! Veronika, a Carinthian mountain cow flexibly uses a βmulti-purpose toolβ to scratch herself. A video and more information will follow in the comments.
www.cell.com/current-biol...
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Jake Smith
Ariane Briegel
2 months ago
CryoET of microbes inside an animal organ? Yes itβs possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!
add a skeleton here at some point
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if you have to do MFA twice in the same "day": go to bed
4 months ago
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reposted by
Jake Smith
Quanta Magazine
5 months ago
Lokiarchaea are tricky to work with in the lab: they grow very slowly, exclusively in an oxygen free environment with the presence of symbiotic bacteria. But with careful nurturing, scientists hope to witness their cell division at work.
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Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine
Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.
https://www.quantamagazine.org/tiny-tubes-reveal-clues-to-the-evolution-of-complex-life-20250908/
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repurposing library monitors
#upthearsenal
5 months ago
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hot (well, cold) off the press! βοΈ well done
@glynnca.bsky.social
&
@michaelgrange.bsky.social
& fabulous co-authors ππΌ
#teamtomo
#cryoET
add a skeleton here at some point
7 months ago
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Delighted to see our work in press! ππ¬π§ Thanks to
@glynnca.bsky.social
,
@michaelgrange.bsky.social
and the rest of the fabulous co-authors for all your contributions. Excited to see where in tissue structural cell biology goes next π!
#liftlaughlove
#teamtomo
#whopper
add a skeleton here at some point
8 months ago
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inspiring and relatable talk from
@alisterburt.bsky.social
#ccpem
10 months ago
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note to self: don't turn out of office replies on
10 months ago
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Jake Smith
bioRxivpreprint
10 months ago
Exploring shaped focused ion beams for lamella preparation
https://www.biorxiv.org/content/10.1101/2025.04.01.646235v1
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reposted by
Jake Smith
Michael Grange
11 months ago
Check out our paper on Xenon milling of HPF samples, now online
@naturecomms.bsky.social
rdcu.be/eczIb
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https://rdcu.be/eczIb
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Barista: How caffeinated would you like to be? Me: Yes
11 months ago
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Jake Smith
Hiro Imachi
12 months ago
Isolated in just 3 years! (previously, 12 years). We obtained two strains from 'Hodarchaeales', proposed to be closest to our archaeal ancestor. Our analysis suggests the ancestor was an anaerobic, syntrophic, peptidotrophic, archaeon with a simple intracellular structure and possible aerotolerance.
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Eukaryotes' closest relatives are internally simple syntrophic archaea
Eukaryotes are theorized to have originated from an archaeal phylum Promethearchaeota (formerly 'Asgard' archaea)1,2. The first cultured representatives revealed valuable insight3,4 but are distantly ...
https://www.biorxiv.org/content/10.1101/2025.02.26.640444v1
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A great opportunity! (especially to hear
@glynnca.bsky.social
spread the plasma gospelππ»)
add a skeleton here at some point
12 months ago
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Congrats Charlie & co.! The use of optogenetics for in tissue CLEM here is really elegant.
add a skeleton here at some point
about 1 year ago
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reposted by
Jake Smith
Jim Woodgett
about 1 year ago
A long read from 2017 but well worth the time for any scientist who both loves their job and and often finds themselves questioning their life decisions.
www.danielnettle.org.uk/wp-content/u...
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https://www.danielnettle.org.uk/wp-content/uploads/2017/09/Staying-in-the-game.pdf
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reposted by
Jake Smith
Jamie Blaza
about 1 year ago
We have quite a range of PhD projects this year, covering cryo-EM methods, bacteriology/bioenergetics, and infection/antibiotics/vaccines. Would really appreciate if people can RT and share with their teams!
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reposted by
Jake Smith
Richard Held
about 1 year ago
Is there such thing as TEMTuesday? Maybe CryoETuesday? Myelinated axon cross section with microtubules and intermediate filaments:
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it is nicer over here
about 1 year ago
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