One thing I didn’t appreciate until London Calling this year is that @nanoporetech.com is now releasing more technical documentation and datasets as blog posts.

New blog post! In it, I benchmark the new version of Dorado from @nanoporetech.com, which comes with new DNA basecalling models. Short version: big accuracy gains for hac, small improvements for sup. Check it out for the full results: rrwick.github.io/2025/05/27/d...

The @nanoporetech.com #EPI2ME team is hiring! If you want to build workflows to analyse @nanoporetech.com sequencing data for end to end applications then this job is for you! ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...

Exciting preprint from Haoyu Cheng (not on bluesky?) and @lh3lh3.bsky.social: building amazing Nanopore assemblies just got faster and more accessible! Thrilled to have played a small part in this work!

Missed our knowledge exchange on Oxford #Nanopore comprehensive metagenomic sequencing for pathogen surveillance? Watch the recording here! buff.ly/IDhJt0S This approach allows for discovery of #bacteria, #fungi, and viruses directly from respiratory samples #metagenomics #viromics

New version of Oxford @nanoporetech.com Dorado v0.9.5

Peter Marks’s resignation letter. Everyone should read this.

Less than two months to @nanoporetech.com London calling. Anyone secretly testing new pores? Kit chemistry? Devices?

This week we celebrated 20 years of innovation! To mark the occasion, we’re offering 20 complimentary in-person tickets to London Calling for researchers facing barriers to attendance. Apply here: share.hsforms.com/1rfrIYeGhTCG... #nanoporeconf

#AGBT2025 #AGBTGM has been incredible. Lucky to be part of the event with @nanoporetech.com - as always we were so looked after by our amazing events team! (Photo credit to @minomatt.bsky.social)

Lanai #190 from 9pm tonight for drinks and canopies with @nanoporetech.com #AGBT2025 #AGBTGM

Stop by the @nanoporetech.com Lanai suite #190 at #AGBT2025 #AGBTGM tonight after the welcome reception. We’re open from 7pm. We can’t wait to PORE you a beverage. 😂

Who's going to #AGBT next week?

Landmark paper claxon! 'Evaluating the economic and health impact of proactive genomic epidemiology in a hospital setting' www.medrxiv.org/content/10.1... Significant savings associated with proactive genomic epidemiology.

Recent #birdflu cases highlight the need for proactive #pathogen monitoring. Read how researchers using nanopore sequencing in wastewater detected surges in #influenza A, showing its potential as an early warning system. Read here: www.the-microbiologist.com/news/sewage-... #H5N1

My 1st “computer” - I remember that genesis motherboard being very in the way when we tried to upgrade the RAM!

Join us next week for a webinar on 🧬nanopore sequencing 🧬 featuring speaker Stephanie Chrysanthou of MSK Cancer Center. Learn about the fundamentals, applications and impacts — and earn CE/CMLE credits. educate.amp.org/local/catalo...

There were remarkable updates presented at #PAG32 on incredibly accurate @nanoporetech.com sequencing for applications ranging from telomere-to-telomere plant & animal genome assemblies, to amplicon sequencing at massive scale. Here are some highlights in case you missed them (thread)

CompàreGenome: a command-line tool for genomic diversity estimation in prokaryotes and eukaryotes https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-025-06036-0 🧬🖥️🧪 #Rstats https://github.com/gmoro-bioecopest/CompareGenome

Following the announcement of our first speaker Jeff Nivala, we’re happy to announce early bird tickets for London Calling 2025, are now available. Make sure to purchase before 19th Jan to avoid the price increase. Get your ticket here: nanoporetech.com/about/events... #nanoporeconf

1/ We’re excited to announce our first speaker of London Calling 2025 Jeff Nivala will share their groundbreaking ‘proof-of-concept' method showcasing the capability of #nanopore sequencing to read #polypeptide strands. Register here: nanoporetech.com/about/events... #nanoporeconf

Oxford @nanoporetech.com 2024 results: - Commercial performance accelerated in the second half in-line with guidance; underlying revenue growth in the second half was approximately 34% on a constant currency basis

new lab member and a bunch of workhorses (on their makeshift heat sink) @nanoporetech.com

Our research this year covered: 🔬 TB diagnostics and technological innovations 💉 TB vaccines and preventive strategies 💊 Drug resistant #TB (DR-TB) and treatment innovations 🙌 Post-TB care and person-centred approaches 💸 Economic and #PublicHealth impacts of TB Find them here:

Merry Christmas! Smoked port old fashioned to finish me off 🥂

Due to the limitations of short read sequencing, this mutation has remained hidden for more than 25 years since ASPA mutations were first characterized in individuals Canavan disease. 2/

I gave the @seqera.io @nextflow.io AI the challenge of writing me a workflow that produced a really grumpy Christmas message. Damn guys - what you been feeding this thing??

This is mega!

New release of Canu - first one in over 3 years! github.com/marbl/canu/r... The notes say this will be the very last release. Many thanks to its devs Brian Walenz and @sergek.bsky.social. Canu may be a bit old and it's certainly not fast, but it makes good assemblies and so I still use it!

🎄 New Dorado release (v0.9.0) – and it's big! 🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka ⚡ Faster modified base calling models 🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling github.com/nanoporetech...

In #NextGenSequencing news, Oxford @nanoporetech.com has released a new version of their basecalling software with new functionalities. An explainer ow what the basecalling software is and what this new release brings for ONT users. github.com/nanoporetech...

@nanoporetech.com #EPI2ME Christmas party tonight!!!

We generate a Nanopore only assembly and use long-read cDNA sequencing for annotation. This give us >99.999% consensus accuracy... no need for short reads or PacBio anymore.

The things you find around the @nanoporetech.com headquarters! #WYMM

Please share with your Biomedical & Clinical Science friends on 🦋 - let’s build our network up again❤️

Thought it was time I joined @nanoporetech.com on here - follow me for the latest #EPI2ME tweets… probably the odd smattering of trains and travel too.