Our hitchhiking paper is out at genomebiology.biomedcentral.com/articles/10.... great collaborative effort with Prasad Sarashetti, @jlipovac.bsky.social, Filip Tomas and JJ Liu. Briefly, the nanopore is enough for high-quality human genomes. Recently, HERRO showed that even UL is sufficient. 1/3

Long-read special issue of GR is out, including our paper on T2T assembly using only Nanopore. Just in time for ONT to discontinue duplex cells on Nov 27 😅😂 Good thing Verkko also works great with HERRO-corrected simplex data! 📄 genome.cshlp.org/content/34/1... 📖 genome.cshlp.org/content/34/1...

Gapless assembly of complete human and plant chromosomes using only nanopore sequencing https://genome.cshlp.org/content/early/2024/11/04/gr.279334.124 🧬🖥️

It's the 6-week countdown to The Biodiversity Genomics Academy 24, and we 30 fantastic and unique sessions! You can join us at discord.gg/HBPytGx6sU to keep up to date with information and other attendees! Session list: thebgacademy.org/BGA24/BGA24 #BGA24 #Bioinformatics #Biodiversity #Genomics

Complete genomes for the apes! We have added bonobo, chimp, gorilla 🦍, orangutan 🦧, and gibbon to the T2T family! Lots of very cool stories buried in these genomes, some of which we have explored here, but I expect many more studies to follow: www.biorxiv.org/content/10.1...

ModDotPlot preprint is now out! Winner of best poster at RECOMB 2023, it can generate either static or interactive dotplots in minutes using hierarchical modimizers. With @alexsweeten.bsky.social and @mikeschatz.bsky.social Preprint: www.biorxiv.org/content/10.1... Code: github.com/marbl/ModDot...

We are looking for a new director of the NIH Intramural Sequencing Center! Please spread the word: www.genome.gov/careers-trai...

10 years on, @bkille.bsky.social @treangen.bsky.social and co. have refreshed Parsnp with a version 2! Build a core genome multi-alignment for 100k SARS genomes or 1k Mtb genomes in under an hour 💨

Our new Center for Genomics and Data Science Research at NHGRI – which my own research group is now a part of – is seeking tenure-track or tenure-eligible investigators to join our program. Check out the ad and get your applications in by January 1! www.genome.gov/careers-trai...

We are excited to release v1.0 of our HG002 genome benchmark today! Our goal with the Q100 project is to create a complete and perfectly accurate representation of the diploid HG002 genome to serve as a replacement for current variant-based benchmarks. More info here: github.com/marbl/HG002

"The p-Arms of Human Acrocentric Chromosomes Play by a Different Set of Rules" An excellent review by Brian McStay on these newly completed regions of the human genome and why you should care: www.annualreviews.org/doi/abs/10.1...