Sachin Kotak
@spindlebehavior.bsky.social
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📥 96
📝 13
Cell Biologist interested in fundamental cell division processes working @iiscbangalore
pinned post!
Happy to see our work on how Aurora A kinase orchestrates nuclear organization by regulating the material properties of spindle pole–localized NuMA at mitotic exit featured on the cover. Grateful to the students for creating this beautiful image!
add a skeleton here at some point
21 days ago
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reposted by
Sachin Kotak
sveta-lab
19 days ago
Proud of two covers from India this year in JCB....both so beautiful,
@rpadinjat.bsky.social
and
@spindlebehavior.bsky.social
add a skeleton here at some point
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Happy to see our work on how Aurora A kinase orchestrates nuclear organization by regulating the material properties of spindle pole–localized NuMA at mitotic exit featured on the cover. Grateful to the students for creating this beautiful image!
add a skeleton here at some point
21 days ago
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reposted by
Sachin Kotak
The EMBO Journal
3 months ago
New Aurora A kinase role in maintaining proper nuclear shape organization at mitotic exit: NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes Sachin Kotak
@spindlebehavior.bsky.social
et al
www.embopress.org/doi/full/10....
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Happy to share our work in @embojournal 👉
shorturl.at/zXNyn
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division? Follow this thread to know more 👇
3 months ago
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reposted by
Sachin Kotak
Shweta Tyagi
6 months ago
It’s happening on the 15th!!
#centrosome
,
#microtubules
,
#centromere
,
#mitosis
,
#cellbiology
@kaustuvsanyal.bsky.social
@viji-draviam.bsky.social
@spindlebehavior.bsky.social
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reposted by
Sachin Kotak
Rockefeller University Press
6 months ago
The cover of
@jcb.org
's July issue (
rupress.org/jcb/issue/22...
) shows a confocal timelapse imaging of
#Celegans
one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (Adhikary et al.
doi.org/10.1083/jcb....
)
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