Owen Siggs
@osiggs.bsky.social
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Lab Head and Program Director, Garvan Institute of Medical Research
reposted by
Owen Siggs
The Wall Street Journal
6 months ago
Regeneron Pharmaceuticals said it will acquire substantially all of 23andMe’s assets for $256 million after coming out on top at a bankruptcy auction for the once-sizzling DNA-testing startup
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Regeneron to Buy 23andMe Out of Bankruptcy for $256 Million
Regeneron Pharmaceuticals said it will acquire substantially all of 23andMe’s assets for $256 million after coming out on top at a bankruptcy auction for the once-sizzling DNA-testing startup.
https://buff.ly/nHp46mB
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Owen Siggs
Pradeep Natarajan
7 months ago
Very excited to share our preprint led by M. Levin
@skoyama.bsky.social
J. Woerner & with S. Damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations!
www.medrxiv.org/content/10.1...
@medrxivpreprint.bsky.social
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Owen Siggs
Eric Topol
7 months ago
A high polygenic risk score (PRS) for screening prostate cancer was superior to a PSA test or MRI for detecting clinically significant disease (Gleason ≥7). A big step forward for supporting utility of PRS
@nejm.org
www.nejm.org/doi/full/10....
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Assessment of a Polygenic Risk Score in Screening for Prostate Cancer | NEJM
The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have identified...
https://www.nejm.org/doi/full/10.1056/NEJMoa2407934
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Daniel MacArthur
11 months ago
I chatted to
@stuartbuck.bsky.social
about scientific funding in the US and Australia, organisational incentives, institutional senescence, and the joy of seeing other researchers doing clever things with data you released:
goodscience.substack.com/p/interview-...
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Interview with Daniel MacArthur
This is an interview with Daniel MacArthur, whom I first met when he was at Harvard Medical School, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard in Boston.
https://goodscience.substack.com/p/interview-with-daniel-macarthur
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