These data incompletely explain the nuance of physician behavioral change when provided with procalcitonin results, but – somehow – mortality decreased from 16% to 13%. #medsky www.evidencetriage.com/p/procalcito...

Good job – you didn't miss the diagnosis when this formerly-rare disease finally trickled into your ED. Now what? #medsky www.acepnow.com/article/i-fo...

You can treat everyone to prevent them from getting sick – or, just wait until they get sick, and then treat them, then? Early data not terribly compelling for CDL in "intermediate risk" PE. #medsky www.evidencetriage.com/p/cathetered...

Turns out generative AI can sometimes make some very convincing radiographs, and radiologists (and LLMs) struggle to catch all the fakes. #MLsky #medsky www.evidencetriage.com/p/deepfake-d...

Challenging the dogma of "increased fluid intake to reduce renal stone recurrence" – but limitations in the study, well, limit the reliability of final judgement on the topic. #medsky www.evidencetriage.com/p/does-fluid...

Perhaps this is the beginning of Ragnarok.

Even more perverse, “robust” TSA screening has never been shown to be more than security theatre to start with.

Grifter kings love the king of the grift.

🎼 I am the walrus. 🎶

Putting HFNO on hypoxemic respiratory failure is probably non-inferior to standard therapy, but there are likely clues clinicians rely upon it longer than they ought when patients actually need mechanical ventilation. #medsky www.evidencetriage.com/p/high-flow-...

The SWiFT trial didn't see a difference between whole blood and balanced blood component transfusion when initiated prehospital for major trauma. Always possible the study did not enroll quite the right population or have the right protocol, but .... #medsky www.evidencetriage.com/p/whole-bloo...

Ignore AI in #radiology at your peril, unfortunately. Interestingly, however, as this (very small) report notes – *where* AI fits in the workflow might matter as far as a perceived "duty of care" to the a patient harmed by a missed diagnosis. #medsky #mlsky www.evidencetriage.com/p/more-littl...

How do I delete my account

Good eyes or good display? MacBook Pro 16" .... What's My JND? 0.0032 Can you beat it? www.keithcirkel.co.uk/whats-my-jnd... #WhatsMyJND

Son: Dad, I’ve read all my books. What can I do now? Me:

Sooo *don’t* drink the river?

A lovely study from Canada doesn't show much favoring rivaroxaban over apixaban for acute VTE – will it be the same for all other indications? #medsky www.evidencetriage.com/p/is-rivarox...

Get your war on.

It's Google Deepmind's AIME project, deployed as a front-end information-gathering tool for urgent care physicians at BIDMC. It was "fine". Probably some bits left unsaid (particularly around clinical acceptability), but still moving forward. #medsky www.evidencetriage.com/p/deepmind-a...

Also: "Z, the country’s largest holder of oil, has about 400 million litres of stock held in tanks across New Zealand – the equivalent of 17 days cover .... Z will always have three ships within seven days of a New Zealand port carrying another 144 million litres." thespinoff.co.nz/partner/08-0...

Easy to look back in prior official releases and grossly confirm this is true. Not the most ... conveniently located reserves. www.beehive.govt.nz/release/new-...

I did not expect this government's terrible idea to bite them on the ass so quickly and thoroughly, but it is darkly humourous #nzpol

The brain drain continues – the U.S. has lost arguably its most important scientific awards ceremony: arstechnica.com/science/2026...

Time to pass a law that any party spokesperson of media outlet that opines with hindsight reckons on pandemic management has to show this chart in the background at all times #nzpol

Here is a full implementation of the Chinese Room using a printed copy of GPT-1 in case you have a few spare years and want to actually run the thought experiment for real, for some reason. You can also download 80 volumes of GPT-1 weights for free to do it: weights-press.netlify.app/pdfs/The-Chi...

🤔 www.ksl.com/article/5145...

When this came round last night, I said to my wife "I have an idea, but I am reluctant to inflict it on people", but I have thought of a was of showing the actor that is less confrontational. So, worst you say... ------ Your job is to pick the worst actor to play James Bond.

Prasad also made collages of doctors wearing masks to shame them and spread doubt and mistrust. That’s the professionalism and maturity he brought to the table.

Everyone wants a symptom checker, a navigator, a chatbot – you name it – to magically direct patients to the "correct" next step in care. Well, this is what Ada Health is claiming their symptom digester will do: #medsky #mlsky www.evidencetriage.com/p/how-do-sym...

Makary claims he’s headed back to UCSF, however. 😑

No self-respecting university ought ever hire him again.

Everyone loves a good poop joke – or poop study. Here's a look at potentially using emergency department-specific wastewater monitoring to detect and characterize viruses circulating in the community: #medsky www.evidencetriage.com/p/whats-in-y...

A scheduling web app, but “Canoodle” instead of “Doodle”.

Can we offload some simple, routine radiology to AI? Not quite yet – and this is why uptake is so hard, because it requires workflows to be precisely designed as to augment a human-in-the-loop, not disrupt. #medsky #MLsky www.evidencetriage.com/p/a-radiolog...

Don't trust ChatGPT Health – or likely any general health LLM – to give you medical advice in the context of a serious acute illness. Patient triage is clearly outside its functional requirements. #medsky www.evidencetriage.com/p/the-chatgp...

Their CMO generic-emailed me today to join. Just reading the alternative list of imperfect social networks in this thread makes me tired. And then there's the elephant in the room – Doximity has shown physician eyeballs are worth $10B, so far. This feels like a play right in the same wheelhouse.

"The delusion around Grail continues. In what was a seriously flawed trial to start with, it is now clear that even the primary endpoint has not been met." #medsky www.bmj.com/content/392/...

The Zero-Miss Diagnosis, The Final Frontier: aortic dissection. Hundreds of CTs to find a handful of cases, even in Australasia where resource stewardship remains a consideration. Nobel Prize in Medicine for whoever invents A Better D-Dimer, please. #medsky www.evidencetriage.com/p/what-does-...

Now I just need the API to connect this to my 3D printer and we're in business.

And vaccines.

‪Doctors say that vaccines protect children from dangerous diseases. A nepo baby who barbecues dogs and snorts cocaine off toilet seats says that vaccines make children vulnerable to 5G radiation. For busy parents, it can be hard to know who to trust.

Physicians are good drivers of LLMs, but regular humans who don't know how to tell the "textbook story" can get dangerously divergent results. #medsky #MLsky www.evidencetriage.com/p/humans-llm...

8 more children died from influenza complications last week, according to CDC's FluView report, bringing the total to 60 pediatric deaths so far this season. The agency keeps tabs on childhood deaths caused by the flu, but doesn't recommend flu shots as a way to prevent infection👇

Vinay continuing to demonstrate his utter intellectual dishonesty and cowardice. #medsky www.nytimes.com/2026/02/10/h...

A lot of scope creep for thrombolysis in CRAO – but, no, the higher quality data emerging shows harms outweigh the benefit. #medsky www.evidencetriage.com/p/do-not-use...

Jay's passion for replication famously only applies to research he doesn't already agree with.