#Medtronic press release on our pivotal #ELEVATE-HFpEF RCT which will test the efficacy & safety of a personalized elevated #pacing rate (based on LVEF & height) in #HFpEF 75 countries 2 patients enrolled already (AUS & US) Methods to be presented at #HFSA25 news.medtronic.com/2025-09-15-M...

FDA announces approval for #semaglutide 2.4 mg sc weekly for #MASLD based on results of the #ESSENCE #RCT. Did you know that #CVD is the leading cause of death in patients with #MASLD? Common mechanisms & now, common treatments for #CKLM diseases www.novonordisk.com/news-and-med...

📣 How is the American Heart Association fighting for medical research & patient care on Capitol Hill? @ahascience.bsky.social #CardioSky #AHA Join Heart Powered: The AHA is Advocating for You 🗓️ June 26 | 🕒 3 PM ET 🎙️ Dr. Bradley Marino & Emily Hubelowski 🔗 Register: heart.zoom.us/webinar/regi...

I love my outdoor #office, where work and play are fully intertwined! What does your #Saturday morning look like? #HappySeason #HomeSweetHome #JoyInWork

It’s impossible to uncouple #health from #economic policy Healthiest countries have fair economic policies that allow upward mobility & access to healthier lifestyles Focusing on individual interventions alone: inadequate www.thelancet.com/journals/lan...

Phase 3 Trial of #Semaglutide in #Metabolic Dysfunction–Associated #Steatohepatitis In patients with #MASH and moderate or advanced #liver #fibrosis, once-weekly semaglutide at a dose of 2.4 mg improved liver steatohepatitis & fibrosis at 72 weeks t.co/vfcgItgXpb

Regional disparities in participant #enrolment in RCTs are related to regional #disparities in site recruitment relative to 🌎disease distribution We propose estimating site representation index during trial planning to ensure globally (or nationally) representative #RCT popn doi.org/10.1002/ejhf...

#NUDGECKD #ERA25 LBT #KristofferSkaar & #TorBiering SimPub #Circulation Pragmatic 2x2 factorial #implementation RCT Randomization at cluster + individual level E-letters re #GDMT to 1540 GPs & 22617 patients w #CKD did not ⬆️ uptake of #RASi or #SGLT2i www.ahajournals.org/doi/10.1161/...

The #sun rose and put on a show just for me! #LifeOnTheLake #Sunrise #LakeMuskoka

Huge Danish trial of nudges Patient level (N 22,000) + practice level (1500 practice cluster with N 28,000 pts) To increase RASination & Flozination www.ahajournals.org/doi/abs/10.1... in @ahajournals.bsky.social at #ERA25 Absolutely null effect - is the baseline too high to improve upon?

Pill splitting guide for patients who take a lot of pills... Which ones are safe to divide? myheartsisters.org/2016/12/04/p...

#Happy season is here! #LifeOnTheLake #LakeMuskoka #Sunsets

Missed the deadline? Plot twist: You didn't! Deadlines extended! 🗓️ #AHA25 & #ReSS25 abstracts now due 6/9 at 10am ET. Award applications due 6/9 at 7pm ET. Submit here: 🔹 AHA: bit.ly/2025Extension 🔹 ReSS: bit.ly/ReSSExtension @ahascience.bsky.social #CardioSky

🚨 Missed early registration? No problem. You can still sign up for RISE @ ESC Congress 2025, the essential event for women in cardiology. 📍 Madrid | 🗓️ Aug 28 🎯 Leadership on the Global Stage Register now 👉 rise.womenasone.org #LetsRISE2025 #ESCCongress #WCCardio #CardioSky #WIC

Ship of #tolerance, created by 2000 school children in our town and displayed in #OakvilleGalleries #GairlochGardens Such a collaborative, moving art display, with ideas communicated in a way that only kids can do.

“The true north is indeed, strong and free” A balanced and appropriate speech from the throne on this historical day. Climate change and biodiversity were woven into this speech alongside, not mentioning by name he who shall not be named. m.youtube.com/watch?v=FCzk...

Interplay of CKD & Effects of #Tirzepatide in Patients With #HFpEF & Obesity: SUMMIT Trial #CardioSky #NephroSky #JACC www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social @dlbhattmd.bsky.social @hmkyale.bsky.social @chriskramermd.bsky.social @psatishmd.bsky.social @drmonalidesai.bsky.social

The sweetest word in the world, the one I’m most grateful to hear each day, is #mum. #MothersDay2025

Is #Aficamten Plus #Disopyramide More Effective Than Aficamten Alone in obstructive HCM? #CardioSky #JACCHF www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social @jimjanuzzi.bsky.social @robmentz.bsky.social @hvanspall.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social

While #health systems across🌎 are designed around #acute illnesses, 86% of yrs lived w disability & 71% yrs of life lost are from #chronic diseases Burden of chronic dz ⬆️ in higher income countries & w age How to move needle? See our analysis @Nature.bsky.social rdcu.be/ek1MH

📢 #CardioSky #MedSky #NephSky join us👇for our @ahascience.bsky.social #HTNImpact webinar! 🌟Faculty @jordybc.bsky.social @daichishimbo.bsky.social + more provide insights on #BP Timely @amjhypertension.bsky.social State of Art Review #AI to improve #BP Control academic.oup.com/ajh/article-ab…

Today, we voted to protect our #sovereignty, freedom, environment, economy, people, We voted for knowledge, alliances, respect, strength, unity We voted to care about those with less so that every kid has a chance to build #CanadaStrong #ViveLeCanada #April2025

Canadians go to #polls today Counting on us to elect a strategic, steady leader who will protect #Canada’s - sovereignty - environment - economy - education - healthcare - global alliances Counting on us to reject politics of anger, fear, division #TrueNorth #CanadaStrong

Happy #AdministrativeProfessionalsDay, dear Robin Thank you making magic happen in my professional life & in our program every day Thank you for being a caring friend in the truest sense of the word Thank you for being incredibly kind to our patients I’m so #grateful for you

#ClimateChange threatens health and livelihood, commonly displacing people. Children are among the most vulnerable. www.unicef.org/stories/3-wa...

I voted on #EasterSunday for - A builder of #bridges, not walls - A strong #economy - Strategic international #partnerships - Environmental #sustainability - Data-informed #policy - #Education & #healthcare for all - #Respect for all Did you #vote?🇨🇦 #CanadaStrong #CanadaElection2025

New in CJASN: Our meta-analysis of 66 CKD trials shows both acute & chronic GFR slope independently predict clinical outcomes Findings support 3-year total slope as the optimal surrogate endpoint for CKD trials @asnpublications.bsky.social: doi.org/10.2215/CJN....

#Light over darkness #Hope over despair #Faith over fear #HappyEaster #Easter2025

“Let everything you do be done with love.” - 1 Corinthians Happy Easter from my home to yours! #Easter2025

Per source, NIH has been instructed to hold off from issuing ALL awards to Harvard, Cornell, Columbia, Brown, and Northwestern (including med schools) Agency staff have also been instructed to not speak about this funding freeze to grantees and applicants

Was honoured to talk to Dr Joseph Hill, EIC of Circulation @ahajournals.bsky.social about his career path, our era of medical disinformation, & power of effective scientific #communication. Brilliant, accomplished, honest, humble, he’s among the best of the best! #Publishing tinyurl.com/2sdsuk7h

The #TarteAuChocolat was delicious, but the note was even sweeter! I never take our privilege for granted. #Cardiology #Medicine #Chocolate

New 2025 #CONSORT guidelines for #RCT #reporting standards The 30 checklist items ensure transparent reporting, but adherence is suboptimal & only required by some journals (onlinelibrary.wiley.com/doi/10.1002/ej…) Essential for trialists + editorial/review teams!www.bmj.com/content/389/...23

“The administration’s prescription goes beyond the power of the federal government. It violates #FirstAmendment rights and exceeds the statutory limits of the government’s #authority under Title VI.” www.harvard.edu/president/ne...

Is there a better time of day? (Featuring my favourite cup from grad school days) #5AM #SundayMorning

#Nudges are behavioral interventions that influence decisions without restricting choices or giving incentives This 2x2 factorial #RCT will evaluate effect of 🇩🇰 nationwide electronic letter nudges delivered to people with #CKD, their GPs, or both on #GDMT www.sciencedirect.com/science/arti...

Canadian #researchers w US federal funding must now confirm that research does not 📌include climate / environmental justice component 📌contain diversity, equity & inclusion elements 📌ascribe to “gender ideology” Some knees bend to money Others wont www.globenewswire.com/news-release...

📢 Call for Papers: #JACCAdvances seeks submissions for a focus issue on Implementation Science & CV Learning Health Systems. Submissions may include pragmatic trials, digital infrastructure, & more. 📅 Deadline: April 15 🔗 bit.ly/43QfNcu

Is anyone aware of any #RCT that demonstrated the efficacy of any intervention in any CVD on the primary #endpoint of “days alive and out of the hospital”? If so, please share. (And what #breakfast are you having to fuel the clinical workday?) #DAOH #TrialDesign

This State-of-the-Art Review addresses the current understanding on the pathophysiological link between #CVD and #CKD, clinical implications and challenges academic.oup.com/eurheartj/ad... #CardioSky @escardio.bsky.social @cardioobdoc.bsky.social @hvanspall.bsky.social @novitham.bsky.social

📌E.g. of #Coanda effect: jet passing through an orifice that abuts a curved surface will deviate from ipath & adhere to surface 📌Due to entrainment of fluid from downstream chamber into jet, creating low P area around jet margin (towards which jet moves) #EchoFirst #MR #Flail

When you take a break from hospital clinical services to meet @vkittipibul who is visiting @PHRIresearch as part of @DCRIFellows exchange program..

Wonder what makes #healthcare systems successful? Read this #GlobalRounds 📑 on #Denmark led by Tor Biering-Sorensen in #Circulation @AHAjournals.bsky.social Economically just society Universal healthcare Strong primary care for every person Enviable clinical & research infrastructure #Cardiosky

Troubling evidence that inadequate exploration of reversible #suffering – lack of access to medical services, poverty, loneliness, and feelings of being a burden – have driven some Canadians to choose #MAiD, now provided with same-day service. macdonaldlaurier.ca/rushing-to-d...

A 💫 finding of run-in phase of #ADVANCE-HTN Ph2b #RCT: 64% ppl with “uncontrolled” #hypertension got BP control in 3 wks through standard genericTx #Aldosterone synthase blocker #lorundrostat 50 mg ⬇️BP at 8wks (w ⬆️K). 100mg: no evidence of added benefit #ACC25 www.radcliffecvrm.com/video-index/...

How wrong is it that a young adult with a heart function like this is managed in the ambulatory setting with… drumroll… digoxin monotherapy!?! Yes, really. #GDMT saves hearts, kidneys, & lives. Only when prescribed. #HeartFailure

Do you publish epidemiologic #data on #CVD? This analysis led by D Abramov & A Mannan demonstrates how different datasets produce different CV death estimates How data are collected, classified, handled matter Check out #CDCWONDER vs #GBD #CVD ☠️ estimates 👇🏽 www.ahajournals.org/doi/10.1161/...

When #endocarditis gets complicated.. #AorticRootAbcess #Fistula #ProstheticValve #EchoFirst

Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation onlinelibrary.wiley.com/doi/10.1002/... #Impella #CardioSky #CardiogenicShock #LVADs @drrajivsankar.bsky.social @shelleyzieroth.bsky.social @cardioobdoc.bsky.social @hvanspall.bsky.social

In this RCT of 504 ppl w #HF (mean age 69 , 67% men, 51% on loop d, all w normal Na+), fluid < 1.5 L/d vs unrestricted 💧 did not ⬆️health status 💧 was associated w ⬆️ thirst distress 💧was not associated w clinical benefit Intake 1.48 vs 1.76 L/d #ACC25 www.radcliffecardiology.com/video-index/...