Cecile Denis
@ceciledenis.bsky.social
📤 231
📥 176
📝 16
Researcher in thrombosis and hemostasis
reposted by
Cecile Denis
TH, Thrombosis & Haemostasis,TH Open
5 months ago
💊 Implementing an Assay to detect Anti-drug Antibody against
#Emicizumab
: Experience from One Center in France 🇫🇷 ⬇️ 📌 Auditeau et al. evaluated the effectiveness of a modified bridging ELISA in detecting anti-drug antibodies Read more: 👉
www.thieme-connect.de/products/ejo...
#hemophilia
#HemeSky
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Cecile Denis
RPTH
5 months ago
Do you diagnose Von Willebrand's Disease? 🩸 Check out this article describing intraindividual variability in VWF levels - suggesting that repeated testing is a key component of the diagnosis and treatment of VWD.
www.rpthjournal.org/article/S247...
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Cecile Denis
Thomas Reiser
6 months ago
For some weekend reading, get to know the
@ISTH.org
2025 Harold Roberts Award Recipient Bob Montgomery better as he shares his journey from basketball🏀to contributing groundbreaking research in
#thrombosis
and
#hemostasis....Enjoy
! 💡
bit.ly/4l8unBw
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Cecile Denis
Nature
6 months ago
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
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Cecile Denis
Kellie Machlus
6 months ago
This please 👇🏼
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Cecile Denis
Alex K
6 months ago
A special day: Jean Solarz, my first PhD student, successfully defended his thesis. Proud of all the work accomplished! Thks to jury members.
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Cecile Denis
Thomas Reiser
7 months ago
Big congratulations to Harry R. Büller 🇳🇱 as the recipient of the prestigious 2025
@ISTH.org
Robert P. Grant Medal for his significant lifetime contributions to the field of thrombosis & hemostasis. A much deserved recognition which we look fwd to celebrating at
#ISTH2025
!
bit.ly/3S2hRqv
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Congratulations Bob! Well deserved recognition.
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7 months ago
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reposted by
Cecile Denis
HITh lab InsermU1176
7 months ago
The lab was present at
#WFHCCS2025
in Dubai!
#VWF
#VWD
#science
#WFH
@hithlabinserm1176.bsky.social
@caterinacasari.bsky.social
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Cecile Denis
James’lab
7 months ago
Our review on the treatment of thrombotic complications in patients with myeloproliferative neoplasms has just been published in the latest issue of Blood, in a “how I treat” series on MPN.
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Cecile Denis
Société Française de Thrombose et d'Hémostase
8 months ago
We are honored to welcome
@riittalassila.bsky.social
to Paris for the French Society of Hematology's talk on Red Blood Cells in Hemostasis. Thank you!
#sfh
#sfth
#hemsky
#hemesky
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reposted by
Cecile Denis
Leo Nicolai
8 months ago
Very happy to contribute another
@bloodjournal.bsky.social
cover with our story on aging platelets:
ashpublications.org/blood/articl...
Thoughtful commentary by Laura Gutiérrez in the issue as well.
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Aging platelets shift their hemostatic properties to inflammatory functions
Key PointsPlatelets change their phenotype as they age in circulation, skewing toward inflammatory function over time.Genetic models of increased platelet
https://ashpublications.org/blood/article/doi/10.1182/blood.2024024901/535225/Aging-platelets-shift-their-hemostatic-properties
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reposted by
Cecile Denis
Alex K
8 months ago
Bravo Jean Solarz for your presentation at the French Society of Hematology on MICAL1
@hithlabinserm1176.bsky.social
#sfh
#Hemsky
#hemesky
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reposted by
Cecile Denis
Caterina Casari
8 months ago
If you missed our paper on the humanized murine model of VWD-type 1 (hVWD1) you can read it
haematologica.org/article/view...
The model provides a novel platform to test therapeutic options for
#VWD
one of which is explored in the paper! Thanks Haematologica for the highlight as Editor’s pick!
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A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options | Haematologica
https://haematologica.org/article/view/11848
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Cecile Denis
International Society on Thrombosis and Haemostasis
8 months ago
Congratulations to the 2025
@rpth.bsky.social
Editor’s Awards Winners! 🏆 These awards recognize outstanding contributions from early career researchers whose work demonstrates excellence and impact. Join us in celebrating this year’s honorees! 📖 Read more:
bit.ly/4lbc7bk
#Thrombosis
#Hemostasis
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reposted by
Cecile Denis
HITh lab InsermU1176
8 months ago
🎉Huge congratulations to Dr Claire Auditeau 🎓 for brilliantly defending her PhD today! And to her supervisors Pr Delphine Borgel and Dr Francois Saller! A big thank you to all the committee members Pr Angelillo-Scherrer, Pr Garçon, Dr Allali, Pr Frere! Happy and proud of your achievement!
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reposted by
Cecile Denis
HITh lab InsermU1176
8 months ago
Happy to share our latest collaborative work on the characterization of the Afro-Caribbean
#VWD
cohort in Martinique island! Congrats Dr Marie-Daniela Dubois and all the authors!
onlinelibrary.wiley.com/doi/10.1111/...
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Clinical, Phenotypic and Genotypic Characteristics of Von Willebrand Disease in Afro‐Caribbeans: Results From a Study in Martinique Island, French West Indies
Background Several cohort studies have investigated the molecular basis of von Willebrand disease (VWD); very few have focused on the Afro-Caribbean population. Objectives To determine the genotyp...
https://onlinelibrary.wiley.com/doi/10.1111/hae.70003
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reposted by
Cecile Denis
Alex K
8 months ago
We have worked for 2 years with
@dianvanderwaldr.bsky.social
to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis
www.jthjournal.org/article/S153...
#hemsky
#hemesky
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Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: Communication from the ISTH SSC Subcommittee on Platelet Physiology.
Platelets contain many heterogeneous carbohydrates (glycans): often capped by sialic acid. The removal of sialic acid (desialylation) is important for platelet function and clearance, leading to novel...
https://www.jthjournal.org/article/S1538-7836%2825%2900193-X/fulltext
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Congratulations to both recipients! As a previous mentee of Pr. Denisa Wagner, I can only confirm how deserving she is of this award.
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8 months ago
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Scary
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8 months ago
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reposted by
Cecile Denis
Alex K
8 months ago
Great collaboration with Hana Raslova and
@alessandrabalduini.bsky.social
teams on BSS signaling defect! Recently published.
@hithlabinserm1176.bsky.social
haematologica.org/article/view...
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Early View | Haematologica
https://haematologica.org/article/view/11965
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reposted by
Cecile Denis
Graduate School Health and Drug Sciences
9 months ago
[CONFERENCE] The Health and Drug Sciences Graduate School invite you to attend the conference “Boosting chimeric antigen receptor T cell therapy via a synthetic vaccine “ by multi-award-winning Dr Leyuan MA. Registration :
admin-sphinx.universite-paris-saclay.fr/v4/s/16eckx
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reposted by
Cecile Denis
Haemnet
9 months ago
Women affected by
#haemophilia
often experience delayed diagnosis. This means not having access to the treatment & care they need, impacting quality of life and putting them at risk of serious bleeding. Time to bust the myth that
#women
don't have haemophilia.
#womenbleedtoo
#HemeSky
#BloodSky
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9 months ago
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Cecile Denis
Université Paris-Saclay
9 months ago
Stand Up for Science France UPSaclay engagée pour la science et la liberté académique Le 7 mars, notre communauté universitaire se mobilise pour défendre la recherche, la transmission des savoirs & la formation de l’esprit critique, indispensables à l’avenir de nos sociétés 🔗
tinyurl.com/28yvvk4p
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reposted by
Cecile Denis
HITh lab InsermU1176
9 months ago
Congratulations to our colleague @Dr Jildaz Caroff for successfully obtaining his HDR (Habilitation à diriger des recherches)!! 👏🏻👏🏻👏🏻👏🏻
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reposted by
Cecile Denis
HITh lab InsermU1176
9 months ago
In the
@hithlabinserm1176.bsky.social
we love to collaborate! Check out this very interesting paper by @Prof Elisa Rossi with valuable contributions by
@alexkzis.bsky.social
and
@ceciledenis.bsky.social
from our group!
www.nature.com/articles/s42...
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Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia - Communications Biology
Thrombin cleaves membrane-bound endoglin and soluble endoglin, releasing fragments of varying sizes; these findings emphasize the heterogeneity of sEng in preeclampsia, connecting endothelial dysfunct...
https://www.nature.com/articles/s42003-025-07751-3
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reposted by
Cecile Denis
Doctors Without Borders
10 months ago
The loss of services supported by USAID will affect millions of the world’s most vulnerable people. Here's our statement on how the freeze of US foreign aid assistance will result in humanitarian disaster:
www.doctorswithoutborders.org/latest/freez...
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Freeze of US foreign aid assistance will result in humanitarian disaster
Loss of services supported by USAID will affect millions of the world’s most vulnerable people
https://www.doctorswithoutborders.org/latest/freeze-us-foreign-aid-assistance-will-result-humanitarian-disaster
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Cecile Denis
International Society on Thrombosis and Haemostasis
10 months ago
The ISTH Announces Recipients of the 2025 Esteemed Career Awards🎉 This prestigious award celebrates individuals whose contributions in thrombosis and hemostasis shaped the field and inspired the scientific community. Stay tuned as the ISTH shares in-depth profiles of each awardee:
bit.ly/3El3wly
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Cecile Denis
ProfMakris
10 months ago
The paper from Alok Srivastava about the use of lentiviruses (rather than AAV) to deliver gene therapy in
#hemophilia
A is in the current issue of the New England Journal of Medicine. It requires an autologous transplant, so will not be acceptable to everybody.
tinyurl.com/ytj6u53r
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Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A | NEJM
Severe hemophilia A is managed with factor VIII replacement or hemostatic products that stop or prevent bleeding. Data on gene therapy with hematopoietic stem-cell (HSC)–based expression of factor ...
https://tinyurl.com/ytj6u53r
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reposted by
Cecile Denis
European Commission
10 months ago
Today, we remember all the victims murdered during the Holocaust. We mark the 80 years since the liberation of the Nazi concentration and extermination camp Auschwitz-Birkenau. This memory must be passed to future generations.
#HolocaustRemembranceDay
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New publication from a collaborative study with the lab of Pr Eikenboom in Leiden (LUMC:
ashpublications.org/bloodadvance...
Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs
10 months ago
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reposted by
Cecile Denis
Société Française de Thrombose et d'Hémostase
11 months ago
La Société Française de Thrombose et d’Hémostase (SFTH) est désormais sur Bluesky ! 🌟 Rejoignez-nous pour échanger autour de l’hémostase, de la thrombose et de l’innovation scientifique. Suivez-nous pour rester informés de nos actualités et événements ! 🩸💬
#SFTH
#Thrombose
#Hémostase
#Medsky
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reposted by
Cecile Denis
Caterina Casari
12 months ago
Congratulations to our colleague Regis Bobe for obtaining the French HDR title today! 👏🏻👏🏻 @InsermU1176 HITh
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reposted by
Cecile Denis
Thomas Reiser
12 months ago
The
@isth-official.bsky.social
is seeking your input on which scientific topics & new therapies in
#thrombosis
&
#hemostasis
you would like to learn more about in 2025. Please take this short survey outlining your top areas of interest & learning preferences.
https://tinyurl.com/bde6wtfc
#HemeSky
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reposted by
Cecile Denis
Nicolas Gendron
12 months ago
😵Just discovered what may be the first case of a VITT-like condition following an infection in a young patient was French 🇫🇷, reported in 2010 and published in a French journal. You can translate the article for more information.
#antiPF4
#VITT
#HIT
🔗
pubmed.ncbi.nlm.nih.gov/21159583/
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reposted by
Cecile Denis
Caterina Casari
12 months ago
Everything you wanted to know about our humanized
#VWD-type
1 mouse model (hVWD1 mice) is now available here ⬇️
haematologica.org/article/view...
#InsermU1176
#HITh
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reposted by
Cecile Denis
International Society on Thrombosis and Haemostasis
12 months ago
✨BIG NEWS!✨The ISTH is thrilled to announce the 2026 Congress will be in Paris, France! Join thousands of global experts in thrombosis & hemostasis for a week of cutting-edge science, collaboration, and innovation 📅: July 11-15, 2026 📍: Paris Expo Porte de Versailles
bit.ly/3BaAwf3
#ISTH2026
#ASH24
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reposted by
Cecile Denis
Fionnuala Ní Áinle
12 months ago
Presenting our vision on the future of the
@isth-official.bsky.social
Guidelines & Guidance committee: ✔️Advancing knowledge translation ✔️Promoting collaboration ✔️Ensuring diversity, equity, and inclusion.
#Thrombosis
#Hemostasis
#Medsky
@jthjournal.bsky.social
www.jthjournal.org/article/S153...
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Cecile Denis
ProfMakris
12 months ago
Really good article in
@jthjournal.bsky.social
about how to deal with persons who have von Willebrand factor levels of 30-50%. The key is how "significant bleeding phenotype" is defined.
tinyurl.com/y55mwkj3
#willebrand
#VWD
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Cecile Denis
Nathan Connell, MD, MPH
12 months ago
CoreVWD is published! CoreVWD was created through a modified Delphi process to generate a consensus list of outcomes for clinical trials for both factor and non-factor VWD therapies. This will ensure that clinical trials evaluate what is most important to the VWD community.
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A core outcome set for prophylaxis and perioperative treatment of von Willebrand disease: The coreVWD initiative
Introduction Treatment options are expanding for von Willebrand disease (VWD). A core outcome set (COS)—a minimum set of agreed-upon outcomes to be used in every clinical trial for a given condition.....
https://doi.org/10.1111/hae.15122
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reposted by
Cecile Denis
Alisa Wolberg, PhD
about 1 year ago
Get ready to submit your research to the ISTH 2025 Congress in DC! Abstract submission site opens this Friday, November 29th. Submit your work for presentation to an intl audience & connect w/ others from around the 🌎:
www.isth2025.org/abstracts
🩸
#hemesky
#hemostasis
#thrombosis
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ABSTRACTS | ISTH 2025 Congress
Submit your abstract by January 15, 2025.
https://www.isth2025.org/abstracts
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reposted by
Cecile Denis
Altmetric
about 1 year ago
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky
#HigherEd
#Altmetrics
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Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
https://docs.bsky.app/docs/advanced-guides/intent-links
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reposted by
Cecile Denis
ProfMakris
about 1 year ago
It is great to see the organisations and journals I closely work with joining BlueSky.
@isth-official.bsky.social
@eahad.bsky.social
@rpth.bsky.social
@jthjournal.bsky.social
If you are involved in thrombosis and hemostasis or hemophilia, consider following them.
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Karin!!! What a star! Congratulations.
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about 1 year ago
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Nice! Looks a bit like Mario Kart
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about 1 year ago
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reposted by
Cecile Denis
Journal of Thrombosis and Haemostasis
about 1 year ago
Mathematical models showed that concizumab enhances thrombin generation by simultaneous inhibition of multiple TFPI anticoagulant activities.
#hemophilia
#concizumab
#TFPI
#medsky
#hemesky
www.jthjournal.org/article/S153...
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If you would love to understand how structural studies have helped us to understand VWF better, but like me, you are not very "biophysic compatible", have a look at our latest review just published in Blood.
ashpublications.org/blood/articl...
about 1 year ago
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reposted by
Cecile Denis
Ben Samelson-Jones, MD, PhD
about 1 year ago
Here is our just published review in
#Blood
focusing on how new biological insights into
#FVIII
are setting the stage for new
#hemophilia
therapies.
#hemesky
#medsky
authors.elsevier.com/a/1k8Qn1UYwn...
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Stunning video!
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about 1 year ago
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