🫀 Management of Antithrombotic Therapy in Left Ventricular Thrombus ⬇️ 📌 Valeriani et al. report a Position Paper of the Italian Society of Hemostasis and Thrombosis (SISET) on the management of left ventricular #thrombosis 🆓 on TH! 👉 www.thieme-connect.de/products/ejo... #CardioSky #HemeSky

🦠 Can coagulation parameters be used to identify #Sepsis subphenotypes? ⬇️ 📌 Wang et al. identified 4 sepsis subphenotypes based on coagulation parameters 📌 The 4 groups showed different prognosis and clinical characteristics 🆓 on TH! 👉 www.thieme-connect.de/products/ejo...

🌏 Are Asian patients with #AF at higher risk of bleeding? ⬇️ 📌 Kang and colleagues compared East Asian and white Europeans 🩸 East Asian had lower 5-year incidence of bleeding, but a trend towards ⬆️ ICH 🆓 on TH! 👉 www.thieme-connect.de/products/ejo... #HemeSky @liverpoolccs.bsky.social

SEPTEMBER ISSUE ONLINE 🚩 International Consensus on #LAAC for the Non-implanting Physician #Apixaban and #Aspirin for #PVT after Laparoscopic Splenectomy for Cirrhotic #VTE with #Edoxaban: ETNA VTE #FactorXI Levels in #STEMI Undergoing #PCI More at: tinyurl.com/mu2d2nbr

HIGHLIGHTS FROM AUGUST ISSUE 🗣️Expert Guidance for Severe #Bleeding on #OralAnticoagulation 💊 #Antiplatelet for High Ischaemic and Bleeding Risks Patients After #PCI Validity of #DIC Based on ICD-10 in a Claims Database read more: tinyurl.com/2ssjnsv2

🩸 Von Willebrand Factor as a Therapeutic Target in Thrombotic Disorders ⬇️ 📌 Jongejan and colleagues review the evolution of VWF-targeting therapeutic agents, their developmental stages and clinical indications 🆓 on TH! 👉 www.thieme-connect.de/products/ejo... #HemeSky

🩸 What is the risk of Major Bleeding During Concomitant Use of #Antiarrhythmics and Oral Factor Xa Inhibitors? ⬇️ 📌 Choi et al. found that Amiodarone, Diltiazem and Verapamil were associated with ⬆️ #bleeding risk, while Dronedarone was not Read👉 www.thieme-connect.de/products/ejo...

🆕Clot, Clot, Who’s There? Ep 6 🎙️ : When Time is Limb ⏱️🦵 JoMarie Monzon hosts Drs. Cassra Arbabi, Donald Baril & Makis Avgerinos for a high-stakes talk on acute limb ischemia (ALI)—🩺 recognition, ⚡ urgency & 🌍 U.S./EU strategies to save limbs & lives. 👉 vln.thrombosis.org/c/podcasts/c...

🧠 Optimal Lipid Management following Ischemic Stroke ⬇️ 📌 Kolios and colleagues provide a comprehensive overview of lipid-lowering strategies for post-stroke patients Read more: 👉 www.thieme-connect.de/products/ejo... #Stroke #Lipid #NeuroSky

📣 Subsegmental vs. More Central Pulmonary Embolism in Lung Cancer ⬇️ 📌 Authors showed similar #VTE recurrence in pts with subsegmental vs. more central PE 📌 Symptomatic #DVT, tumor stage, EGFR mutations and anticoagulation 🔗with VTE recurrence 👉 www.thieme-connect.de/products/ejo...

📣 Venous #Thromboembolism in #cancer and non-cancer patients managed with patient-centric protocol ⬇️ 📌 Cancer patients had higher risk of VTE recurrence and major bleeding 📌 Rates of complications were substantially lower compared to #VKA era 👉 www.thieme-connect.de/products/ejo...

📣 International Clinical Practice Guidelines Recommendations for Prevention, Diagnosis, and Management of Central Venous Catheter #Thrombosis ⬇️ 📌 Rosson and colleagues reviewes CPG recommendations on CVC-associated thrombosis Read more: 👉 www.thieme-connect.de/products/ejo...

📣 How to Manage Venous #Thromboembolism Risk during #Pregnancy in Patients with Inherited Antithrombin Deficiency? ⬇️ 📌 Mauge and colleagues from the French Society of Thrombosis and Haemostasis (SFTH) report a review and suggestions Read more: 👉 www.thieme-connect.de/products/ejo... #HemeSky

🫀 Endothelial Glycocalyx Integrity and LV performance after #STEMI ⬇️ 📌 Thymis et al. found that reduced #endothelial glycocalyx integrity was associated with worse left ventricular performance at 1-year after STEMI Read more: 👉 www.thieme-connect.de/products/ejo... #CardioSky

🆕 Article on COPD-specific Pulmonary 🫁 Embolism Diagnostic Strategy Read 👀 article here ▶️ www.thieme-connect.de/products/ejo... Read our interview 💬 with the authors ✒️ Vicky Mai and Francis COUTURAUD www.linkedin.com/pulse/copd-s...

Your 5 minute read for today 🤗

🆕 Article on Prevention, Diagnosis and Management 🩺 💊 of Central Venous Catheter #Thrombosis 👀 Read full article here ▶️ www.thieme-connect.de/products/ejo... Read our interview 💬 with the authors ✒️ Marco Rosson and Elena Campello www.linkedin.com/pulse/preven...

🫁 Derivation and Validation of a COPD-specific Pulmonary Embolism Diagnostic Strategy ⬇️ 📌 Mai et al. derived a #COPD-specific algorithm 📌 Diagnostic failure rate: 0.9%; 53.4% patients would need imaging to rule out #PE Read more: 👉 www.thieme-connect.de/products/ejo... #VTE #Thrombosis #HemeSky

💊 Implementing an Assay to detect Anti-drug Antibody against #Emicizumab: Experience from One Center in France 🇫🇷 ⬇️ 📌 Auditeau et al. evaluated the effectiveness of a modified bridging ELISA in detecting anti-drug antibodies Read more: 👉 www.thieme-connect.de/products/ejo... #hemophilia #HemeSky

#Medsky🧪 DOAC for athletes w their fav safety profile, & that individualized strategies. Shared decision-making & regular reassessment of thrombotic &🩸 risks . Athletes involved in high-risk sports & should be discouraged during active anticoagulation & esp when vitamin K antagonists are required.

🆕article on Managing #anticoagulation 💊in #athletes and #sportspeople 🏃‍♀️🏃‍♂️ ➡️ tinyurl.com/3vhxwsar 👀Read our 💬interview with 🖊️authors Elena Campello and Pablo Bucciarelli www.linkedin.com/pulse/managi...

💊 DOAC for Prevention of Venous Thromboembolism after #cancer-related surgery: a Network Meta-analysis ⬇️ 📌 Pititto et al. included 5 RCTs and found that #DOAC reduced #VTE without increase in bleeding Read more: 👉 www.thieme-connect.com/products/ejo... #anticoagulant #thrombosis

📢 JULY2️⃣0️⃣2️⃣5️⃣ ISSUE ONLY 📌Stress 😱, violence 👊and recurrent #VTE 🦵 📌eGFR Decline↘️ is Causally Associated with 🚨Acute Pulmonary 🫁Embolism 📌CD3+ T Lymphocytes in Human Coronary 🫀Thrombi with #STEMI 📖more at tinyurl.com/5hk7kpfb

🆕 Article on #Bleeding Risk Scores in Anticoagulated PE #Patients ➡️ www.thieme-connect.com/products/ejo... 👀 Read our interview 💬 with lead authors ✒️ Yuzhi Tao and Zhenguo Zhai #anticoagulation www.linkedin.com/pulse/bleedi...

📣 Hot off the press: Platelet function in #AF patients treated with #DOAC ⬇️ 📌 Miglionico et al. found that #platelets of AF patients treated with DOACs have altered reactivity Read more: 👉 www.thieme-connect.de/products/ejo... #Thrombosis

📢 New "Clot, Clot" Podcast 🎙️ Episode live from #ISTH2025‼️ A joint effort 🤝from the @isth.org and Vasculearn Network/ @thjournal.bsky.social Thieme Listen to @btsamuelsonmd.bsky.social. Erik Klok and @gbarnesmd.bsky.social about how we talk about #anticoagulation🗣️💊 www.linkedin.com/posts/vascul...

🆕 TH Article on Gut microbiota-platelet axis and thrombosis in advanced chronic liver disease ▶️https://tinyurl.com/4p7dm5y5 👀 Read our interview 🗣️with lead author ✒️Francesco Violi www.linkedin.com/pulse/gut-mi...

📢 JUNE 2️⃣0️⃣2️⃣5️⃣ ISSUE ONLINE 🚩 🩸 #bleeding in #Women of #Childbearing Age on Anticoagulants for #VTE 🚨 Screening-Detected #afib and Blood Pressure Levels 🔬Plasma Proteome and #VTE risk 💊Plasma #DOACs levels in #afib: A Metanalysis 📖More at: tinyurl.com/5hk7kpfb

📣 The new Impact Factor for TH is 4.3! ⬇️ 📌 TH ranks in Q1 in #Hematology and Peripheral #Vascular Disease Read latest articles published on TH: 👉 www.thieme-connect.de/products/ejo...

📣 HMGB1-Platelet interactions: mechanisms and targeted therapy ⬇️ 📌 In this review article, Fang and colleagues discuss the HMGB1-platelet axis and its role in determining diseases 🆓👉 www.thieme-connect.de/products/ejo... #Platelets #Thrombosis #Hemesky

📣 Change in Fibrinogen variants in patients with #Obesity and #MASLD after bariatric surgery ⬇️ 📈 Absolute levels of #fibrinogen higher in pts with BMI >45 📌 Sialylated fibrinogen lower after bariatric surgery 👉 www.thieme-connect.de/products/ejo... #HemeSky #EndoSky

🧬 VWF Variants in Type 2 Von Willebrand Disease: Insights from a German Patient Cohort 🇩🇪 📌 Yadegari et al. report genotype and laboratory phenotypes of 196 families with type 2 #VWD 🆓👉 www.thieme-connect.de/products/ejo... #vonWillebrandDisease #Hematology #MedEd ‪‪@unibonn.bsky.social‬

Did you listen 👂 to our latest Clot, Clot who's there ? Podcast 🎙️ Episode with Vasculearn? ▶️ sites.libsyn.com/564815/site Listen to Jose Joglar and Gregory Lip, on the latest U.S. and European #AFib #guidelines. 👀Read Clinician Perspective Article on ESC guidelines▶️ tinyurl.com/mc6pr936

🆕 TH Article on DOACS 💊 vs Standard Therapy 💉 in Upper Extremity Deep Vein Thrombosis ➡️ www.thieme-connect.de/products/ejo... 👀 Read our interview 🗨️ with first author Pedro Ruiz-Artacho www.linkedin.com/pulse/direct...

🩸 Bleeding Risk in patients with #Cancer-associated VTE receiving DOAC ⬇️ 📌 Vedovati et al. report factors associated with major #bleeding in cancer-associated #thrombosis 📌 Age, steroids, antimetabolites, and unresected GI cancer linked to ⬆️ risk 👉 www.thieme-connect.de/products/ejo...

Read our interview 💬 with lead author ✒️ Jonas Gmeiner on 🆕 article on Heparin Thrombophylaxis for pts on DAPT 👀 Read full article here ➡️ www.thieme-connect.de/products/ejo... www.linkedin.com/pulse/hepari...

🚨 Consensus on the management of Venous Thromboembolism in Special Situations ⬇️ 📖 Marzo et al. report the results of an expert consensus on the management of challenging scenarios in patients with #VTE Read 🆓 on TH 👉 tinyurl.com/4txczdxc #Thrombosis #HemeSky

📖 Platelet disorders and treatments: a comprehensive review ⬇️ 📌 Zhang et al. review common causes of thrombocytopenia and thrombocytosis, and treatments for these two conditions Read on TH 👉 tinyurl.com/bddn7725 #Platelets #HemeSky

🦠 COVID-19 and Platelets: new insights on NO and ROS production! ⬇️ 📌 Petito et al. show that #platelets from #COVID-19 patients have an altered NO/ROS balance, with defective NO and increased ROS production Read on TH 👉 tinyurl.com/thknbmwz #HemeSky #Infection

Geographical 🗺️ and Racial Variation in VTE Outcomes: read our interview 💬 with the lead authors Alfonso Tafur and Manuel Monreal tinyurl.com/bde2zvf4 👀 Read Full article here ➡️ www.thieme-connect.de/products/ejo...

💊 Reducing use of antiplatelets without PPI in pts taking Warfarin - The AEGIS trial ⬇️ 📌 Kurlander et al. show that a multicomponent intervention led to stop antiplatelet or initiate PPI in pts. using Wafarin, antiplatelet and no PPI Read on TH 👉 tinyurl.com/3yykxwps @gbarnesmd.bsky.social

🚨 Factor XI Inhibitors for Myocardial Infarction: A Safer Path to Thrombotic Protection? ⬇️ 📌 In this clinical focus, authors review the potential role of FXI Inhibitors in pts with #MI 👉 www.thieme-connect.de/products/ejo... Author's interview below ⬇️ @dfcapodanno.bsky.social

📌Factor XI Inhibitors 💊for Myocardial Infarction 🫀: A Safer Path to Thrombotic Protection? Read our interview 💬 with lead author Marco Spagnolo ▶️ linkedin.com/pulse/factor... 👀 Read Full Article here ➡️ thieme-connect.com/products/ejo... @dfcapodanno.bsky.social

🚨 Serum MPO-DNA to predict Venous Thromboembolism and effect of #statins in pts. with Intracerebral Hemorrhage ⬇️ 📌 In 117 patients with #ICH, ⬆️ MPO-DNA levels associated with #VTE 📌 Statin use associated with ⬇️ MPO-DNA 🆓 on TH 👉 www.thieme-connect.com/products/ejo... #Thrombosis #HemeSky

TH MAY 2️⃣0️⃣2️⃣5️⃣ISSUE ONLINE ✅#VenousThromboembolism in #Glioblastoma 💉the AGEHA Study: #Emicizumab for Acquired #Hemophilia A 🐹Cardiac Repair after #MyocardialInfarction is Controlled by Complement C5a Receptor 1 Read the complete issue at tinyurl.com/2cjjfxhn

@youngdzhk.bsky.social @dzhk.de @ekfstiftung.bsky.social

🚨 Distal Deep Vein Thrombosis in pts admitted to Internal Medicine wards: the AURELIO study ⬇️ 📌 1,458 pts included; asymptomatic distal DVT found in 4% 📌 53% of distal #DVT extended to proximal tract 📌 Active #cancer and pneumonia 🔗 with DDVT 👉 www.thieme-connect.de/products/ejo...

❓is F11R/JAM-A involved in platelet adhesion and thrombus formation? ✔️Kamola et al. showed that🚫blocking interactions of platelets' F11R/JAM-A with its surface-bound-counterpart compromises thrombus formation 👉 thieme-connect.com/products/ejo...

📑Navigating Anticoagulation 💊 in Ischemic Left Ventricular Aneurysms: Lessons from Cardiac 🫀MRI Read Editorial by Ashkan Hashemi and @bbikdeli.bsky.social www.thieme-connect.de/products/ejo... Original Article 📰 here www.thieme-connect.de/products/ejo...

Resting heart 🫀 and risk 🏥 of VTE Read our interview 💬 with the first author Oda Leknessund ▶️ www.linkedin.com/pulse/restin... 👀 Read full article 📰 here ▶️ www.thieme-connect.de/products/ejo...