Strong alliance, weak conclusions: Comment on Goodwin et al. (2026) “The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression” osf.io/preprints/ps... Many thanks to my coauthors Rick Zeifman, @kangaslampi.bsky.social & @moeswisdom.bsky.social

What a headline.

NY Times Ballot - Best Movies of the Century so far

Reframing Psychedelic Regulation: Tools, not Treatments In this new article, we propose to regulate psychedelics as psychotherapeutic treatment tools rather than as treatments in their own right. The use of anesthetics as treatment tools in surgery is a useful analogy.

🚨🚨New psychedelics paper out today! 🚨🚨 "Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression." psychiatryonline.org/doi/10.1176/... 🧵⬇️

My opinion piece in today’s @nytimes.com . I discuss how clinical neglect of medication-related harms has made RFK Jr’s stance on antidepressants appealing to so many and moving the public conversation in a productive direction requires us to remedy this neglect. www.nytimes.com/2025/05/03/o...

Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity. This ‘fundamental’ study into the effects of #psilocin on human neurons: buff.ly/f7cNemV

Another null result psychedelic trial. This time looking at LSD microdosing for ADHD. Most interesting is the detail showing most subjects in LSD group correctly guessed they got the psychedelic. BUT their benefits still mostly matched the placebo group.

A recent study suggests that no dose adjustment of #LSD is necessary in the presence of an SSRI that inhibits CYP2D6. #psychedelics ascpt.onlinelibrary.wiley.com/doi/10.1002/...

This cause is close to my heart - please sign: weact.campact.de/petitions/sc...

Wir alle, Robert, wir alle

Wenig überraschend ist die größte inhaltliche Übereinstimmung der CDU mit einer anderen Partei, die, mit der AfD. Das macht gemeinsames Abstimmen natürlich mindestens verlockend und lässt es ganz natürlich erscheinen. www.spiegel.de/politik/wahl...

First suicide in legal PAT, in Switzerland (first known case out of around 2000). History of delusions could be a red flag, not clear what the previous delusions and how psychosis-like they were. Thanks to the team for publishing this. www.sciencedirect.com/science/arti...

THE 25 BEST FILMS OF 2024 A video countdown vimeo.com/1046284152

Glad to be at #ACNP2024 in Phoenix! On Monday, I will be presenting the results of our episode trial in the session „Psychedelic-assisted Psychotherapy: From preclinical mechanisms to clinical applications“ alongside @fredbarrettphd.bsky.social, @kellietamashiro.bsky.social and Jennifer Mitchell.