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Claude Sonnet....

It's Monday so we're at war again

Do you see what I see? 🧐 www.frontiersin.org/journals/nut...

This one? 🦒

Americans may be unhappy about gas prices and affordability more generally, but at least they can take solace in the President's forthcoming ballroom and new luxury jet.

Could have just doubled the NIH budget this year. Can you imagine?

Seems legit

No one finds it odd (especially the stock market) that almost every positive breaking news on Iran is coming from a single Axios reporter?

Most Americans don't realize just how bad this is. Citizens United levels of bad. Gift article

Depressing to see that jump on "deportations," a sign that the more the Trump admin keeps immigration out of the news, the better for him. When it's highly visible, the American public hates it. When it's people being grabbed quietly without the spectacle, they forget about it and move on.

Suspending elections where people have already started voting so you can gerrymander their voting power away. Very democracy.

👀

"They did it without the support of a single major scientific organization."

The scope of these terminations is unprecedented. At RFK Jr's HHS alone, 77 advisory boards were disbanded in 2025 — more than a quarter of all the panels. For context: in 2024, HHS terminated just two. Among the casualties: panels on organ transplantation, dietary guidelines, and long COVID.

The Trump administration is downsizing US science by historic margins — but it's not just via funding or workforce cuts. Our new @nature.com analysis reveals the government has cut more than 100 scientific advisory panels across major agencies. w/ @alexwitze.bsky.social @dangaristo.bsky.social

One element of the Accountability Agenda needs to be vows of future consequences for those individuals, companies, and foreign governments engaged in bribery or other corruption with members of the administration or their family members.

Started to watch "Civil War" on the plane ride back to Chicago. Had too many feelings, stopped watching. People like Marsha don't actually care about Tennesseans.

As I get an email from my house representative who is 84 and has been in this position since.... 1997

I think we are beyond the we just need to vote on big and small elections. We need better, moral, engaged, normal people to run for office. In places like Chicago it always feels like we vote but there's no choice (both systematic reasons and lack of candidates).

With very ominous language, Justice Elena Kagan says that today’s decision in Louisiana v. Callais ends the Supreme Court’s “now-completed demolition of the Voting Rights Act.” 6-to-3 vote in favor of white voters who challenged a Black-majority district in La. www.supremecourt.gov/opinions/25p...

What in the AI is this in the United app? How and why is this AI?

I'll be giving an informal presentation in a couple of weeks. I believe there are several external attendance spots left:

Wow. To all those throwing up their hands and saying “what can we do?,” read this thread. Colette is a freaking grad student (complimentary). What is your excuse?

🧵1/n Yesterday was the first day of #SDDS2026. It was highly informative and engaging and, while it doesn't do it justice, I wanted to distill just 2 common themes I took away (note: these are my personal observations, from memory. I believe the talks were recorded.)

Chemistry World article about academic freedom worldwide and in the US. www.chemistryworld.com/news/academi... 1/3

"Science Committee Democratic staff have learned from multiple sources that President Trump has fired the entirety of the National Science Board (NSB)."

"For climate change, vaccines, etc. we see a lot of friction..." 3/4

"80% of the CDC's highest positions are vacant, with directors of 20 out of 25 centres having left. An estimated 2000 staff, almost one in five, have been fired, and about 300 are on administrative leave."

There is no authority. Congress never authorized this war. The President lacked authority under Article II to start this war. And the war violates Article 2(4) of the UN Charter.

They paused Oversight Committee hearings the minute we started getting answers about the Epstein files. Now it’s “roundtables”: no rules, no oaths, no subpoenas. You do the math. Because the moment accountability shows up, they shut it down. The survivors deserve better.

I'll be giving an informal presentation in a couple of weeks. I believe there are several external attendance spots left:

This is good news, with a caveat. The gap in funding is still devastating for many small businesses because we've missed 2 application cycles, meaning the earliest funding is a full year from right now (April 202)

Heading to Stanford next week for #SDDS2026. In 7 months, Evoquant has built: - A 5.2M biosynthetic gene cluster atlas - An AI platform predicting natural product–target interactions - A wet-lab pipeline with confirmed bioactivity in 6/6 validation cases (15 in progress) 🧵

This is the kind of betrayal a nation carries out when its leaders don't believe in the concept of allies and that views promises as something for suckers. It also makes our armed forces less safe. No nation will ever trust us again. Why should they? We stab our friends in the back.

We're looking to connect with companies interested in partnering to advance our compounds, out-licensing from our pipeline, and investors exploring the space. Whether you want to talk business or just talk science, find @chasingmicrobes.bsky.social at the Corporate Poster Session (Apr 27–28).

New strain is strikingly red. Moreso in real life.

Bacterium: Here, look, I made this for you

Those of us doing research related to women’s health have been hit particularly hard by the govt’s sabotage of the NIH. I spoke to WaPo for this piece, as painful as it was to discuss the reality my lab is facing. www.washingtonpost.com/science/2026...

The new normal... At war on Monday before US Markets open "Peace" by Friday before US Markets close

Very good (if tragic) story from the Washington Post [GIft Link] wapo.st/3OONwh6 1/8

How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism: merenlab.org/2026/04/15/u...

"A concept of a peace plan"

The Palantir post, summarized: White, USA, religious nationalism is the path forward. We should be allowed to do and say whatever we want. Silicon Valley is able to, and should be left to, fix all the world's problems. Trust us bro.

Trump: I'm rolling back progress towards oil dependence. Make oil great again! Also Trump: I have now disrupted a significant portion of our oil supply!

In the past just the fact the President publishes official government communication via a distribution platform he owns and makes money off of (Truth Social) would be scandalous. Now all the more heinous scandals make that one seem tame. And that's partly the point What are we doing as a society?

Where has this molecule been detected before across samples, organisms, body parts, and environments? With StructureMASST, you can explore this directly by entering a molecule name and running a search in your browser. 🔗 structure-masst.gnps2.org 📄 www.nature.com/articles/s41...

People on X making really apparent why Anthropic is so strict about blocking science related content in its latest models. (e.g. "Claude helped me set up a lab in my basement") Which sucks for scientists with access to proper facilities who would benefit greatly from using these models.