Eric Ma
@ericmjl.bsky.social
đ¤ 760
đĽ 48
đ 105
Senior Principal Data Scientist, Moderna. Trying to follow Jesus.
Why does AI leave us both supercharged and exhausted? AI moves fast, but our brains have limitsâand that's where burnout hits. I've learned the hard way that syncing my workflow to my brain's pace matters most. Ever hit this wall? Drop your thoughts or tips!
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Calibration Is Synchronizing Feedback Loops With Neural Throughput
written by Eric J. Ma on 2026-04-04 | tags: productivity burnout attention feedback calibration multitasking exhaustion kanban workflow ai
https://buff.ly/d8Yzs7j
6 days ago
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AI can code, but it can't architect your app. Human judgment keeps code maintainable. I turned 8,500 lines of AI-coded chaos into a plugin systemâhereâs what I learned. Ever cleaned up AI code? Repost or share your story!
buff.ly/R1AIDyY
#softwarearchitecture
#aicoding
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Undoing AI vibe-coded slop with AI
written by Eric J. Ma on 2026-03-29 | tags: ai llm coding architecture plugins opencode tools
https://buff.ly/R1AIDyY
13 days ago
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How do you keep mentoring and leading when budgets are tight? You donât need big budgetsâyour skills and network are enough. Here are 5 budget-free ways Iâve helped others grow at work. Whatâs your go-to strategy? Comment or share!
buff.ly/lAKet1K
#.mentorship
#.careergrowth
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Creative mentorship strategies for career growth in challenging times
written by Eric J. Ma on 2026-03-25 | tags: mentorship leadership coaching networking growth development creativity teamwork community learning
https://buff.ly/lAKet1K
20 days ago
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Whatâs the hidden bottleneck in your workflow? Air gapsâmanual steps we ignoreâadd up fast. I share how spotting and closing these gaps saved me time and energy. Have you found air gaps in your work? Comment or repost if this rings true!
buff.ly/lhmOcqL
#automation
#workflow
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Closing air gaps
written by Eric J. Ma on 2026-03-15 | tags: automation efficiency airgaps workflow processes agents imagination skill mapping labs
https://buff.ly/lhmOcqL
27 days ago
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Are agent skills just for bots, or do they shape how we work too? Workflow skills reveal our habits, not just automate tasks. My daily sign-off skill bakes in my workflowâcontext matters! What do your automations say about you?
buff.ly/flUlA9W
#.agentskills
#.workflow
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Agent skills are also human skills
written by Eric J. Ma on 2026-03-14 | tags: automation documentation workflow context dependencies github obsidian productivity skills structure agents
https://buff.ly/flUlA9W
about 1 month ago
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PyMC in your browser? It worksâjust not with NUTS! WASM lets PyMC run client-side, but NUTS is still missing. Spent my weekend getting PyTensor running in WASM. Learned a lot, but NUTS is still out for now. Would you use PyMC in-browser? Repost or comment!
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My weekend experiment making PyMC installable in a WASM environment
written by Eric J. Ma on 2026-03-08 | tags: python pymc bayesian webassembly pyodide
https://buff.ly/6Sw3IHi
about 1 month ago
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Drowning in work chaos? Plain text + AI agents keep me organizedâno vendor lock-in. My Obsidian + Python workflow isnât perfect, but itâs saved me hours and stress. How do you manage info overload? Comment or repost!
buff.ly/BvEYHq8
#.pkm
#.aiworkflow
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Mastering Personal Knowledge Management with Obsidian and AI
written by Eric J. Ma on 2026-03-06 | tags: agents ai obsidian knowledge management productivity workflow
https://buff.ly/BvEYHq8
about 2 months ago
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Are coding agents making you better, or just faster? Speed means nothing if you lose control of your analysis. I found that slowing down and adding structure led to 5-10x speedupsâwithout chaos. Does this match your experience? Repost or comment!
buff.ly/mbVjECO
#datascience
#ai
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How to stay in control when doing EDA with coding agents
written by Eric J. Ma on 2026-02-13 | tags: agents ai data science exploratory data analysis workflow productivity
https://buff.ly/mbVjECO
about 2 months ago
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Agentic coding is transforming data science. AI is a collaborator, not just a tool. I distilled 10 lessons from real ML projectsâlike agent journals and prescriptive prompts. These tips saved me days and sparked new ideas. Which tip would you try?
bit.ly/409K82l
#datascience
#aiagents
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How to Do Agentic Data Science
written by Eric J. Ma on 2026-02-01 | tags: agentic coding experiments logging reports journal plots iteration structure exploration
https://bit.ly/409K82l
2 months ago
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Eric Ma
SciPy Conference 2026
2 months ago
đŁ
@ericmjl.bsky.social
is teaching an "Agentic Data Science" workshop to raise funds for
#SciPy2026
đď¸ March 27 & April 3, 2-4 PM EST đď¸ $1,000 minimum donation ($200 for students) đď¸ Sign up at
agent-assisted-data-science.vercel.app
đď¸ Pay to NumFOCUS (tax-deductible) at
givebutter.com/RBJuGI
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Model 'feel' can make or break your coding flow. Harness and feedback loops often matter more than model scores. Switching models and adding fast tests changed my workflow for the better. Agree? Repost or share your experience!
buff.ly/Nv2cC1k
#ai
#devlife
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Model feel, fast tests, and AI coding that stays in flow
written by Eric J. Ma on 2026-01-25 | tags: llm autonomy supervision personality verbosity harness refactoring workflow testing ergonomics
https://buff.ly/Nv2cC1k
2 months ago
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Teaching an "Agentic Data Science" workshop to raise funds for SciPy 2026. Compress weeks of work into a day using coding agents. March 27 & April 3, 2-4 PM EST Google Meet 40 spots, $1,000 min donation paid directly to NumFOCUS (tax-deductible) Sign up:
buff.ly/P1T2mh3
1/n
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Agentic Data Science Workshop | SciPy 2026 Fundraiser
Learn how to compress 2 weeks of work into 1 day using coding agents. A fundraiser workshop for SciPy 2026.
https://agent-assisted-data-science.vercel.app/
2 months ago
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Treat your coding agent like a teammate, not a chatbot. I think the trick is knowing when to update
AGENTS.md
vs create a skill. I share my simple model for evolving agent workflows and building real leverage. Whatâs your approach? Comment or share!
buff.ly/FluyXjj
#.aiagents
#.devworkflow
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How to build self-improving coding agents - Part 3
written by Eric J. Ma on 2026-01-19 | tags: agents ai workflows productivity skills
https://buff.ly/FluyXjj
3 months ago
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Tired of repeating the same coding steps? Skillsâmarkdown playbooksâmake agents smarter and your life easier. I share how skills saved me time and made team know-how reusable. Would you try skills? Comment or repost!
buff.ly/rTPYdMf
#.ai
#.automation
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How to build self-improving coding agents - Part 2
written by Eric J. Ma on 2026-01-18 | tags: agents ai skills mcp workflows
https://buff.ly/rTPYdMf
3 months ago
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Tired of repeating yourself to coding agents? Agents should actually learn from our feedback. AGENTS .md and simple playbooks helped my agents improve week by weekâless babysitting, more progress. Tried this? Let me know or repost!
buff.ly/5qi4pic
#.ai
#.automation
3 months ago
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Eric Ma
Mayor Zohran Kwame Mamdani
3 months ago
ICE murdered RenĂŠe Good in broad daylight. Less than 3 weeks later, they killed Alex Pretti, shooting him 10 times. Every day, we watch as people are ripped from their cars, their homes, their lives. We can't allow ourselves to look away from this cruelty. Abolish ICE.
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Bioinformatics fixed my browser bug. DNA sequence alignment beat string normalization for messy text highlighting. Smith-Waterman, a DNA algorithm, solved my canvas-chat issue. Cross-domain ideas really work! Ever tried a wild fix? Comment or share!
buff.ly/wnq3Ewz
#.webdev
#.algorithms
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How I fixed a browser selection bug with sequence alignment algorithms
written by Eric J. Ma on 2026-01-06 | tags: javascript bioinformatics katex canvas algorithms bugfix highlighting selection web development ui
https://buff.ly/wnq3Ewz
3 months ago
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First contact with GLM-4.7 and... yeah, it feels a lot like Opus 4.5. One-shotting coding problems. I gotta probe where its limits are.
3 months ago
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Ever wish LLM chats could branch like your thoughts? Linear chat holds us backâso I built Canvas Chat for nonlinear exploration. Open-source, infinite canvas for branching and merging ideas with Claude, GPT, and more. Repost or comment if this sparks ideas!
buff.ly/KaFK4fR
#.ai
#.opensource
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Canvas Chat: A Visual Interface for Thinking with LLMs
written by Eric J. Ma on 2025-12-31 | tags: ai llm opencode claude visualization tools productivity
https://buff.ly/KaFK4fR
3 months ago
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AI themed my tmux barâno plugins needed. AI let me focus on design, not syntax. Claude + OpenCode turned ideas into a terminal I love. You just need vision! How has AI changed your workflow? Repost or comment!
buff.ly/aCXmjK1
#tmux
#aipairprogramming
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How I Themed My tmux with OpenCode + Claude (And When to Switch Models)
written by Eric J. Ma on 2025-12-27 | tags: ai opencode claude tmux terminal creativity workflow pair-programming
https://buff.ly/aCXmjK1
4 months ago
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I don't code anymoreâI build. AI lets me ship projects by describing what I want, not how to do it. In 10 days, I shipped 6 projects with OpenCode + Claude Opus 4.5. The gap between idea and product is tiny now. Would you try this? Repost or comment!
buff.ly/blroW24
#ai
#buildfast
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You Can Just Make Stuff with OpenCode and Claude Opus 4.5
written by Eric J. Ma on 2025-12-28 | tags: ai opencode claude automation workflow llm reasoning development review tools
https://buff.ly/blroW24
4 months ago
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atggaacgccgctattgccatcgcattagcaccatggcgagcgcgaacgatcatgcgccgccgtataacgaatggtatgaagcgcgc! (if you know, you know what to do!)
4 months ago
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đMerry Christmas to all! 104 blog posts. 2 years. Hereâs what changed for me. Writing weekly turned AI into a true collaborator. Lessons on coding agents, Bayesian stats, and biotech leadershipâshared honestly. What did 2025 teach you? Comment or repost!
buff.ly/Kkebg57
#blogging
#datascience
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Two years of weekly blogging and what 2025 taught me
written by Eric J. Ma on 2025-12-25 | tags: blogging retrospective coding agents llms bayesian biotech career writing marimo modal data science
https://buff.ly/Kkebg57
4 months ago
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Why do your best work if your company wonât notice? I think itâs about investing in yourself, not just your job. I share how building reputation and resilience pays off down the road. Ever had effort pay off later? Comment or share!
buff.ly/SyXPuJc
#careeradvice
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The selfish reason to do your best work
written by Eric J. Ma on 2025-12-17 | tags: career growth work philosophy resilience reputation leadership mistakes success advice
https://buff.ly/SyXPuJc
4 months ago
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Stop letting coding agents run wildâtake control for better results. AI is a collaborator, not just a tool. My top tips: plan with AI, write docs/tests first, and use
AGENTS.md
as your agentâs guidebook. Got your own agent tips? Share below!
buff.ly/kudW7pd
#aiagents
#productivity
5 months ago
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reposted by
Eric Ma
Altmetric
9 months ago
3. A massive 24 year long Danish study demonstrated that, no, aluminium adjuvants in vaccines are not dangerous. They save around 4 million lives a year (11k lives A DAY.)
www.altmetric.com/de...
Explained in glorious detail by @sailorrooscout.bsky.social here:
bsky.app/profile/sai...
4/8
add a skeleton here at some point
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'Folk statistics' is costing science billions. AI can help, but only if we build it right. I built an AI stats agent for experiment designâsharing what worked, what failed, and why prompts matter. Faced these issues? Repost or comment!
buff.ly/UGinNw9
#ai
#statistics
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What does it take to build a statistics agent?
written by Eric J. Ma on 2025-12-02 | tags: statistics biotech reproducibility experiments research automation ai data open source bayesian
https://buff.ly/UGinNw9
5 months ago
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Coding agents can access any repoâno workspace limits! Just give Copilot or Claude the file path and skip the hassle. I stopped copying files and juggling configs. Itâs way simpler than I thought. Would you try this? Comment or share!
buff.ly/EP7thlP
#codingagents
#productivity
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How to Reference Code Across Repositories with Coding Agents
written by Eric J. Ma on 2025-11-17 | tags: automation coding agents workflows productivity ai filesystem reference workspaces shell
https://buff.ly/EP7thlP
5 months ago
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307 lines of agent codeânow just 4. Graph-based LLMs are clearer and more powerful. PocketFlow let me rebuild my AgentBot with a tiny, declarative graph. Cleaner code, instant visualization, and a new mindset for agents. Would you try this? Repost or comment!
buff.ly/vQo50AX
#llm
#aiagents
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How I Replaced 307 Lines of Agent Code with 4 Lines
written by Eric J. Ma on 2025-11-16 | tags: llm graphs agents automation pocketflow llamabot python workflows abstractions state
https://buff.ly/vQo50AX
5 months ago
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Coding agents can wreck your repo in seconds. Auto-approve only read-only commandsânever risky ones. I share my setup for safe agent autonomy and lessons learned. How do you keep agents in check? Comment or repost!
buff.ly/PetnnVz
#ai
#automation
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Safe ways to let your coding agent work autonomously
written by Eric J. Ma on 2025-11-08 | tags: automation productivity coding agents safety workflow development prompting command line ai
https://buff.ly/PetnnVz
6 months ago
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AI agents + Marimo notebooks = Python on autopilot. Letting AI write and check my Marimo code is a total workflow upgrade. The --watch flag and marimo check catch errors fast and keep me moving. Would you try this? Repost or comment!
buff.ly/6LDN1RV
#python
#datascience
6 months ago
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By definition, AI agents are always going to be out of date. AI agents need live, searchable knowledge. I share how LlamaBot's MCP server keeps docs fresh and accessible for any LLM agent. How can this help you? Repost or comment!
buff.ly/5td8FNC
#ai
#documentation
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How to expose any documentation to any LLM agent
written by Eric J. Ma on 2025-10-19 | tags: llm documentation ai mcp workflow context search knowledge development automation
https://buff.ly/5td8FNC
6 months ago
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Skills cut token costsâMCP servers win for sharing. Which is better for LLMs? Skills = fast, local tweaks. MCP = team standard. I compared Anthropic's skills repo to MCP serversâreal trade-offs, not just hype. Which would you use? Repost or comment!
buff.ly/zhV1XfO
#llm
#aiworkflows
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Exploring Skills vs MCP Servers
written by Eric J. Ma on 2025-10-20 | tags: anthropic skills token efficiency llm automation customization workflows development mcp
https://buff.ly/zhV1XfO
6 months ago
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Coding agents flop without real workflowsâprompts aren't enough. Discipline and feedback loops make agents useful. TDD-first, external memory, and fast iteration changed my game. Whatâs your best agent tip? Comment or share!
buff.ly/yH5Hjkv
#aicoding
#devworkflow
7 months ago
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What if your coding agent could remember your preferences?
AGENTS.md
lets you train your LLM agent like an employee. This one file made my workflow smootherâno more repeating myself! Would you try this? Repost or comment!
buff.ly/LinjaUs
#.aiagents
#.devtips
7 months ago
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Ultralearning is a superpower to mastering tough skills quickly. Courses aren't enoughâself-driven ultralearning is the real unlock. I break down how ultralearning helps you grow fast, whether it's bio, software, or any field. What will you ultralearn next?
buff.ly/2l4z68Z
#ultralearning
#growth
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How data scientists can master life sciences and software skills for biotech using ultralearning
written by Eric J. Ma on 2025-10-01 | tags: biotech ultralearning datascience lifesciences software learning career skills modeling feedback
https://buff.ly/2l4z68Z
7 months ago
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Still fighting Python environment headaches? Iâve moved to pixiâautomation and new tools are the future. My Data Science Bootstrap Notes now use pixi, uv, and AI. This is my recommended workflow for 2025. Would you make the switch? Comment or repost!
buff.ly/MoXJJhL
#.datascience
#.python
7 months ago
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AI isnât just for codeâhereâs how I use it to boost my career. LLMs help me prep for negotiations, updates, and tough convos. 10 ways I save time and stand out at work, with prompts you can steal. Which would you try? Comment or repost!
buff.ly/OkXup6p
#aihacks
#careerdevelopment
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How to use AI to accelerate your career in 2025
written by Eric J. Ma on 2025-09-01 | tags: productivity negotiation presentations llm automation communication competencies ghostwriting updates ai
https://buff.ly/OkXup6p
7 months ago
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Ever wonder why your stats brilliance doesnât land with lab scientists? Clarity beats complexity every time. Hereâs how I learned to lead with decisions, not methods. Whatâs your best tip for bridging the gap?
buff.ly/8Zuli8E
#biotech
#datatips
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How to communicate with lab scientists (when you're the data person)
written by Eric J. Ma on 2025-08-24 | tags: biotech communication decisions statistics translation collaboration trust meetings probability stakeholders
https://buff.ly/8Zuli8E
8 months ago
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đĽ You can rewrite Python functions live! Itâs wild, risky, and opens up new AI tricks. I tried dynamic patchingâsuper powerful, but security is a real concern. Hereâs what I learned. Would you try this, or is it too risky?
buff.ly/RqGBgE1
#python
#ai
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Wicked Python trickery - dynamically patch a Python function's source code at runtime
written by Eric J. Ma on 2025-08-23 | tags: python runtime llm security namespace compilation execution functions toolbot monkeypatching
https://buff.ly/RqGBgE1
8 months ago
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Are data scientists obsolete now that LLMs can code? I see LLMs as tools that reshape, not replace, our work. Experimenting with LLMs has made our scientific mindset more valuable than ever. Whatâs your take? Repost or comment!
buff.ly/o9PnXhR
#llms
#datascience
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Data scientists aren't becoming obsolete in the LLM era
written by Eric J. Ma on 2025-08-15 | tags: productivity workflows evaluation metrics business science models ai tools measurement
https://buff.ly/o9PnXhR
8 months ago
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reposted by
Eric Ma
Jeremy Lewi
9 months ago
I've been eval pilled by
@hamel.bsky.social
. Everyone is all let's build some MCP servers and ship a minimal AISRE as quickly as possible. And I'm writing a design doc about how to build evals with
@runme.dev
so we can iterate rapidly on the AI
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Eric Ma
Indrek Kalvet
8 months ago
RFdiffusion2 is now live!
github.com/RosettaCommo...
You can now design proteins, and in particular enzymes from just partially defined amino acid side chains, and without defining their sequence position or order!
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Stop guessing priorsâR2D2 puts you in control. I think R2D2 is a breakthrough for Bayes modeling. It automates shrinkage and variance allocation for clearer, less overfit models. Would you try this? Repost or comment!
buff.ly/kcbOuG6
#bayesianstats
#statmodeling
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Stop guessing at priors: R2D2's automated approach to Bayesian modeling
written by Eric J. Ma on 2025-08-06 | tags: bayesian variance r2d2 dirichlet multilevel glm regularization priors inference pymc
https://buff.ly/kcbOuG6
8 months ago
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AI can't replace the grindâyou have to earn your automation. My 2-day feature rewrite only worked because of months of prep. I share how struggle made AI a true thinking partner, not a shortcut. Have you tried this approach? Repost or comment!
buff.ly/TG4xOqr
#.ai
#.softwaredev
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From nerd-sniped to shipped using AI as a thinking tool
written by Eric J. Ma on 2025-07-21 | tags: automation ai memory design coding testing architecture prototyping review pairing
https://buff.ly/TG4xOqr
9 months ago
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Eric Ma
E. Rosalie
9 months ago
đ§ľAmericans should really hear how the CDC in other regions talks about us.
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Eric Ma
AltNIOSH
9 months ago
They spread the lie for years that public health professionals are enemies. Now, a policeman is dead, and the lives of CDC personnel and their kids were at risk. There'll be "deep concern" and thoughts & prayers. But architects of that lie will celebrate privately because this has been the goal.
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Police officer dead after âantivaxâ shooter targets CDC headquarters
An active shooter was reported on the Emory University campus in Georgia. The suspect, who was killed, was said to have blamed his illness on the Covid vaccine
https://www.thetimes.com/us/news-today/article/cdc-shooting-antivax-police-officer-dead-9nvvszm6z
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Eric Ma
Jack Hopkins-The Original
9 months ago
CDC Buildings Hit by Gunfire : MAGAâs war on truth works exactly as designed...turn Americans against science, poison them with propaganda, and watch them die from preventable causes⌠all while calling it âfreedom.â This is the bill for their lies.
www.medpagetoday.com/publichealth...
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CDC Buildings Hit by Gunfire
Agency may have been the target of shooter who blamed his illness on COVID shots
https://www.medpagetoday.com/publichealthpolicy/publichealth/116925
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What if all your lab and ML data lived in one place? Index chaos is optionalâxarray keeps everything aligned. I show how this cuts errors and makes analysis smoother. Would this help your workflow? Repost or comment!
buff.ly/6QXFDY4
#xarray
#datamanagement
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How to use xarray for unified laboratory data storage
written by Eric J. Ma on 2025-07-15 | tags: xarray bioinformatics reproducibility cloud workflow alignment features laboratory datasets scaling
https://buff.ly/6QXFDY4
9 months ago
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What keeps me coming back to
#scipy
after 10 years? The communityâs curiosity and generosity are unmatched. From teaching to spontaneous podcast chats, every year brings new inspiration and growth. Got a favorite conference story? Comment or repost!
buff.ly/gRAMkoC
#scipy
#python
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Reflections on the SciPy 2025 Conference
written by Eric J. Ma on 2025-07-14 | tags: scipy python conference marimo tutorials llms xarray community networking career
https://buff.ly/gRAMkoC
9 months ago
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