Roman Pleskot
@rople.bsky.social
📤 41
📥 102
📝 0
reposted by
Roman Pleskot
Vanni Lab at UNIFR, Switzerland
4 days ago
This amazing work by
@danialv.bsky.social
and Bodan Hu is now out in peer-reviewed form at
@cp-cell.bsky.social
with a lot of new simulations! Check it out if interested in lipid transport!
add a skeleton here at some point
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reposted by
Roman Pleskot
Plant Systems Biology
7 days ago
Plants survived the dinosaur-killing asteroid by duplicating genomes, work from
@yvdp.bsky.social
vib.be/en/news?vgo_...
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News
https://vib.be/en/news?vgo_ee=tDN6Se%2FJRaT5xSMdVYhnlIKgfWsG7qfv9Q7j5cAjLokSWA%3D%3D%3AQSNpVpDz31l3bfABeltiL12Y4fmw4vOg#/news/plants-survived-the-dinosaur-killing-asteroid-by-duplicating-genomes?utm_source=ActiveCampaign&utm_medium=email&utm_content=VIBTimes%20June%3A%20Surviving%20the%20dinosaurs%2C%20bacteria%20nets%2C%20and%20an%20Alzheimer%20tipping%20point&utm_campaign=VIBTimes%20May%20-%20split%20%28Copy%29
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Roman Pleskot
José Dinneny
14 days ago
So proud to share our latest publication @CellCellPress! Yue Rui reveals that the same enzyme that makes the wall, cellulose synthase complex (CESA), also tethers the plasma membrane to the wall during water-deficit stress, providing resilience.
sciencedirect.com/science/articl…
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Roman Pleskot
Thomas Ott
13 days ago
Many thanks to Yue Rui and
@josedinneny.bsky.social
for generously involving us into this great story. Amazing appreciation of the work of
@nikolajabel.bsky.social
. Congratulations to all authors.
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Roman Pleskot
Nathan German
14 days ago
What is an edge? Why is this geometrical domain so crucial during plant morphogenesis? Read our review, co-written with Antoine Chevalier and
@ckirchhelle.bsky.social
to find out!
authors.elsevier.com/c/1nAnf4tPF4...
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Roman Pleskot
Michael Hothorn
25 days ago
Team effort from
@fxrico.bsky.social
, Oded, Pierre, Andrea,
@hmchen93.bsky.social
, Larissa now out in
@pnas.org
The Kelch phosphatase BSU1 is a PP1-like serine/threonine phosphatase involved in cell cycle regulation, not a tyrosine phosphatase in brassinosteroid signaling 👍
doi.org/10.1073/pnas...
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Roman Pleskot
Ralph Hückelhoven
26 days ago
I am very grateful to Franz Hagn, his team and colleagues for making this possible. Atomic resolution of the inactive, active and downstream effector ICR/RIP-bound active ROP GTPase RACB. The complex may form a positively charged interface for plasma membrane interaction.
doi.org/10.1038/s420...
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Nucleotide-dependent switching and RIPb effector recognition of the barley susceptibility factor RACB - Communications Biology
High-resolution structures of the plant small GTPase RACB show how switching between inactive and active states enables RIPb effector binding, providing a physical link between the cell membrane and m...
https://doi.org/10.1038/s42003-026-10316-7
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reposted by
Roman Pleskot
Nature Plants
29 days ago
New OA Article: "In situ architecture of plasmodesmata in Physcomitrium resolved by cryo-electron tomography"
rdcu.be/fjjiK
Plasmodesmata are gated by cell wall remodelling; helical protein assemblies scaffold internal membranes; implications for molecular filtering.
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reposted by
Roman Pleskot
Institute of Experimental Botany of the CAS
27 days ago
#newpaper
: Mechanisms controlling the plasma membrane targeting and the nanodomain organization of the plant SPFH protein HIR2
@theplantjournal.bsky.social
: plasma membrane nanodomains, HIR2, S-acylation, lipids, oligomerization, super-resolutionmicroscopy, ROS
doi.org/10.1111/tpj....
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Mechanisms controlling the plasma membrane targeting and the nanodomain organization of the plant SPFH protein HIR2
S-acylation and lipid composition as well as oligomerization control the plasma membrane localization and the organization into nanodomains of the Arabidopsis Stomatin/Prohibitin/Flotillin/HflK/C (SP....
https://doi.org/10.1111/tpj.70879
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Roman Pleskot
The EMBO Journal
28 days ago
A Rab-A2a/Kinesin-12/TIO kinase module couples vesicle delivery and phragmoplast expansion during plant cell cytokinesis Liam Eliott
@liamelliottplants.bsky.social
, Charlotte Kirchhelle
@ckirchhelle.bsky.social
et al
@rdplab.bsky.social
link.springer.com/article/10.1...
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A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis - The EMBO Journal
Cytokinesis is a key process in the development of multicellular organisms, through both formative and proliferative divisions. In land plants, successful cytokinesis requires precise targeting of Gol...
https://link.springer.com/article/10.1038/s44318-026-00804-1
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reposted by
Roman Pleskot
Charlotte Kirchhelle
about 1 month ago
Incredibly proud of this paper showing how plants couple vesicle delivery and phragmoplast expansion during division. This project started in the lab of the great and late Ian Moore, and it was a joy to finish it with
@liamelliottplants.bsky.social
et al!
link.springer.com/article/10.1...
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A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis - The EMBO Journal
Cytokinesis is a key process in the development of multicellular organisms, through both formative and proliferative divisions. In land plants, successful cytokinesis requires precise targeting of Gol...
https://link.springer.com/article/10.1038/s44318-026-00804-1
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Roman Pleskot
Liam Elliott
about 1 month ago
A long road with this one, with many questions still to answer, but out now in
@embojournal.org
! RAB-A2a, Kin12s and TIO interact to coordinate membrane-phragmoplast dynamics during cytokinesis. Big thanks to
@ckirchhelle.bsky.social
for letting me explore this!
link.springer.com/article/10.1...
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A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis - The EMBO Journal
Cytokinesis is a key process in the development of multicellular organisms, through both formative and proliferative divisions. In land plants, successful cytokinesis requires precise targeting of Gol...
https://link.springer.com/article/10.1038/s44318-026-00804-1
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reposted by
Roman Pleskot
bioRxiv Plant Bio
28 days ago
MILDEW RESISTANCE LOCUS O (MLO) proteins function as trimeric inward calcium channels
https://www.biorxiv.org/content/10.64898/2026.05.18.725938v1
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reposted by
Roman Pleskot
Institute of Experimental Botany of the CAS
28 days ago
#newpaper
: A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis
@springernature.com
: Cytokinesis, Dynein, Kinesin, Plant cytoskeleton, RHO Signalling, Protein trafficking in plants
doi.org/10.1038/s443...
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A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis - The EMBO Journal
Cytokinesis is a key process in the development of multicellular organisms, through both formative and proliferative divisions. In land plants, successful cytokinesis requires precise targeting of Golgi-derived vesicles to the future cell division plane by the phragmoplast, a cytoskeletal structure that undergoes continuous remodeling. Endomembrane trafficking and phragmoplast remodeling are tightly coupled, indicating the existence of active crosstalk. However, although many molecular regulators of membrane trafficking and cytoskeletal organization are known, it remains poorly understood how these processes are coordinated. Here, we describe a regulatory module consisting of the membrane-associated GTPase RAB-A2a, cytoskeleton-associated Class II Kinesin-12 proteins, and the Fused kinase ortholog TIO. We provide evidence that the interaction between these molecules at the midzone, and differential functions of Class II Kinesin-12 members at the leading and lagging cell plate domains, are essential for cytokinesis initiation and progression in Arabidopsis by simultaneously targeting vesicles to the midzone and coupling phragmoplast remodeling to vesicle delivery.
https://doi.org/10.1038/s44318-026-00804-1
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reposted by
Roman Pleskot
Jonathan Kaufman
28 days ago
It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of
#biochemistry
,
#cryoET
and
#cellbiology
📝 Paper:
www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo
#membranetrafficking
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Roman Pleskot
Alex Johnson
about 1 month ago
If you ever wondered about the history and current state of plant Clathrin-mediated endocytosis....here is a review just for you!
onlinelibrary.wiley.com/doi/10.1111/...
Was really fun to write this with awesome co-authors! ⚽️🌱🔬
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Clathrin‐Mediated Endocytosis in Plants: Historical to Modern Advances
Ultrastructural studies by Bonnett and Newcomb in 1966 revealed the existence of coated vesicles budding from the plant cell plasma membrane. This review introduces this discovery and early questions...
https://onlinelibrary.wiley.com/doi/10.1111/tra.70037
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reposted by
Roman Pleskot
Marcel Dickmanns | 🌿❄️🔬
about 1 month ago
It's out! 🥳 In situ architecture of
#plasmodesmata
- plant cytoplasmic bridges - by
#cryoET
. 📝 Paper:
www.nature.com/articles/s41...
🧵 Thread:
bsky.app/profile/madi...
#teamtomo
#proteomics
#AlphaFold
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reposted by
Roman Pleskot
bioRxiv Plant Bio
about 1 month ago
The molecular architecture of the Arabidopsis callose synthase complex
https://www.biorxiv.org/content/10.64898/2026.05.05.722910v1
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reposted by
Roman Pleskot
Daniel Van Damme
about 1 month ago
I am looking for a postdoctoral fellow to join my team to work on the interplay between endocytosis and autophagy. The 3-year project runs in collaboration with the Dagdas lab
@plantophagy.bsky.social
and can start asap. Interested candidates can apply via the link below.
jobs.vib.be/apply/134365
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Roman Pleskot
Marija Smokvarska
2 months ago
Acute remodeling of phosphoinositide lipids promotes endocytosis downstream of RALF/FERONIA signaling: Current Biology
www.cell.com/current-biol...
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Acute remodeling of phosphoinositide lipids promotes endocytosis downstream of RALF/FERONIA signaling
Serre et al. reveal that RALF peptides rapidly trigger PI4P-to-PI(4,5)P2 conversion at the plasma membrane downstream of the receptor kinase FERONIA. This acute phosphoinositide remodeling, mediated b...
https://www.cell.com/current-biology/fulltext/S0960-9822%2826%2900314-3
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Roman Pleskot
Michael Wrzaczek
3 months ago
Very cool work by Matteo Citterico. Thanks
@rople.bsky.social
and Martin Potocký for the collaboration.
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Roman Pleskot
Mathilda Lennartz
3 months ago
I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you:
www.nature.com/articles/s41...
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Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology
Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...
https://www.nature.com/articles/s41556-026-01915-x
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Roman Pleskot
Emmanuelle Bayer
3 months ago
PhDs apply to the Cold Spring Harbor Laboratory course Frontiers & Techniques in Plant Science. 1 month of hands-on training with leading experts. A unique opportunity to explore cutting-edge plant science methods and build your network. 🌱
meetings.cshl.edu/courses.aspx...
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Frontiers & Techniques in Plant Science
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
https://meetings.cshl.edu/courses.aspx?course=C-plan
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reposted by
Roman Pleskot
Institute of Experimental Botany of the CAS
4 months ago
#new_paper
: Condensin II mediates resistance to genotoxic stress and prevents mitotic defects in Arabidopsis
@academic.oup.com
doi.org/10.1093/plph...
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Condensin II mediates resistance to genotoxic stress and prevents mitotic defects in Arabidopsis
A forward-directed screen revealed that Condensin II prevents formation of mitotic anaphase bridges and maintains genome stability under genotoxic stress i
https://doi.org/10.1093/plphys/kiag022
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reposted by
Roman Pleskot
Science Magazine
4 months ago
New research provides insight into how division orientation is controlled to ensure robust tissue architecture during plant growth. Learn more in this week’s issue of
#ScienceAdvances
:
https://scim.ag/3Okfjp7
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reposted by
Roman Pleskot
Marie-Cécile Caillaud
4 months ago
What could be more satisfying than this ? ✨️Congrats to all the authors ✨️ Could not be more proud of you 🥹 Credit: Camila Goldy
@camilagoldy.bsky.social
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reposted by
Roman Pleskot
Marie-Cécile Caillaud
4 months ago
What a treat to see the work from Camila Goldy
@camilagoldy.bsky.social
et al.,
@rdplab.bsky.social
@ensdelyon.bsky.social
now published 🫶
www.science.org/doi/10.1126/...
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The actin cytoskeleton is required to maintain plant cell division orientation against cellular geometry
Actin guides plant cell division, shaping tissues in ways that defy geometric constraints.
https://www.science.org/doi/10.1126/sciadv.aeb8498
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reposted by
Roman Pleskot
Akademie věd ČR
6 months ago
🔬 Do laboratoře rostlinných biologů dorazil přístroj, který dokáže zobrazit detaily buněk dosud skryté i moderním mikroskopům. ✨ Nový superrezoluční mikroskop kombinuje tři technologie a nabízí ostřejší snímky i možnost sledovat, jak spolu jednotlivé molekuly v buňkách interagují.
1url.cz/oJYac
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reposted by
Roman Pleskot
Institute of Experimental Botany of the CAS
6 months ago
Proud to be the first institution in Central Europe to host it. Our new Mirava Polyscope from Abberior Instruments brings cutting-edge imaging for plant research at the cellular and molecular level — and is open to external users via Czech-BioImaging.
@ifieb.bsky.social
@czechacademy.bsky.social
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reposted by
Roman Pleskot
Kresten Lindorff-Larsen
6 months ago
Our review on Integrative modelling of biomolecular dynamics 💃 is now live at COSB We discuss approaches to integrate computational methods with time-dependent & time-resolved experiments to study protein dynamics With
@dariagusew.bsky.social
& Carl G. Henning Hansen
doi.org/10.1016/j.sb...
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Roman Pleskot
Michael Wrzaczek
6 months ago
Last one of the year: CRK2 controls the localisation of other RLKs to plasmodesmata. Great collaboration with
@grandpahiro.bsky.social
@rople.bsky.social
and Ivan Kulich - thank you for the help and great collaboration!
add a skeleton here at some point
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Roman Pleskot
David Drubin
7 months ago
Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social
@jiwasa.bsky.social
movie.biologists.com/video/10.124...
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Roman Pleskot
Nature Plants
7 months ago
New Article: "A combined biochemical and computational approach provides evidence for membrane remodelling by the structural scaffold of the endocytic TPLATE complex"
rdcu.be/eP4fX
... to generate a comprehensive structure of the multisubunit endocytic TPLATE complex.
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reposted by
Roman Pleskot
Institute of Experimental Botany of the CAS
7 months ago
#new_paper
: A combined biochemical and computational approach provides evidence for membrane remodelling by the structural scaffold of the endocytic TPLATE complex DOI: 10.1038/s41477-025-02146-y
@natplants.nature.com
www.nature.com/articles/s41...
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Roman Pleskot
Jenny Russinova
7 months ago
Another great collaboration with
@trevormnolan.bsky.social
and
@nvukas.bsky.social
where we give our vision on how brassinosteroid research can pave the way to precision plant engineering
www.science.org/doi/10.1126/...
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Unlocking the potential of brassinosteroids: A path to precision plant engineering
Brassinosteroids are essential plant hormones that play a central role in regulating growth, development, and stress responses. Their impact on plant architecture and productivity makes them attractiv...
https://www.science.org/doi/10.1126/science.adu9798
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Roman Pleskot
Jenny Russinova
8 months ago
Dear ENPER community, We are pleased to invite you to the next ENPER meeting, which will be held in my country Bulgaria, from 26 to 28 August 2026 in Sofia. Save the Date!🌱🌱🌱
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