New publication from Laboratory of Insect Immunometabolomics in collab with Laboratory of Molecular Chronobiology (@akademievedcr.bsky.social) - study shows that the firebug activates its defense mechanisms before it encounters infection or winter conditions 🌗 www.sciencedirect.com/science/arti...

A brand-new Science Sketch has just been published in @cp-trendsbiochem.bsky.social 🎉 👉 doi.org/10.1016/j.ti... We’re especially proud that the author is one of our own PhD students Tereza Dolejšková from the Laboratory of Molecular Integrative Physiology in Drosophila ( @drosophylab.bsky.social)

The new opinion article in Trends in Biochemical Sciences by Pavla Nedbalova and Tomas Dolezal (@drosophylab.bsky.social) from Department of Molecular Biology and Genetics (@kmbg-jcu.bsky.social) provides new insights into the complex role of adenosine! More at authors.elsevier.com/a/1msKv3S6Gf....

We are proud to announce, that our former PhD student, Dr. Karolína Svobodová, has received Dean´s award for her outstanding PhD thesis. Congratulations on the achievment to both Karolina and her mentor Dr. Alena Krejčí (Laboratory of Bee Biology www.prf.jcu.cz/en/faculty/d...)

Excited to share the newest publication from the Alex Bruce lab! PhD students M. Stiborová, A. Hauserová & R. Collier show that p38-MAPKs drive primitive endoderm specification in an ICM-autonomous manner, independent of cavity expansion. @kmbg-jcu.bsky.social l academic.oup.com/reproduction...

Our whitepaper on #ProjectPsyche is online now in @cp-trendsecolevo.bsky.social! Psyche will generate reference genomes for all European butterflies. Just imagine what we’ll be able to learn from them. And if you can’t quite imagine it, have a look at the piece. :)

🟠 25. listopad patří Mezinárodnímu dni za odstranění násilí páchaného na ženách a dívkách. Univerzita Karlova se k této iniciativě připojila společně s dalšími institucemi a symbolicky se zahalila do oranžové. #OrangeTheWorld

Check out the new preprint from the Laboratory of Early Mammalian Developmental Biology ( #LEMDB) from our department! 🐭

Our department spent the weekend in Šumava for the annual PhD retreat — sharing research, ideas, and great company. Between sessions we hiked, enjoyed good food, and soaked in the autumn scenery. Thanks to everyone who made it such a great mix of work and fun! @fscusb.bsky.social

Hospodářská, @petrnguyen.bsky.social et al. investigated genome size and karyotype in Polyommatus and Lysandra butterflies, rejecting polyploidy to confirm karyotypic diversification via chromosome fragmentation in Polyommatinae butterflies. 🔗 doi.org/10.1093/gbe/evaf157 #genome #evolution

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize

📢 Applications are OPEN for the Master’s in Functional Genetics & Bioinformatics! Learn genomics, data science & molecular biology to prepare for research & biotech careers. Apply now 👉 www.prf.jcu.cz/en/faculty/d... #Genetics #Bioinformatics #Masters #LifeSciences #Biotech

📢 Applications are OPEN for the Master’s in Functional Genetics & Bioinformatics! Learn genomics, data science & molecular biology to prepare for research & biotech careers. Apply now 👉 www.prf.jcu.cz/en/faculty/d... #Genetics #Bioinformatics #Masters #LifeSciences #Biotech

The last talk before the coffee break will be given by Lenka Gahurová from the University of South Bohemia, with a fascinating talk about Long-Term Female Fertility of African Mole-Rats #developmentalbiology #fertility #epigenetics #evodevo

National Postdoc Appreciation Week is an annual celebration designed to recognize the significant contributions postdoctoral scholars make to US research and discovery. Join the celebration September 15-19. Visit buff.ly/NVsPBCu for a list of events both virtual and in-person. #NPAW

PhD at Med Faculty, University of Belgrade! Study mitochondria-immune crosstalk in Parkinson’s as part of the MSCA-funded BICEPS network. Join cutting-edge neuroimmunology research! 🌍 🔗 Info: www.membranetrafficking.com/biceps/index... #PhD #Parkinsons #MSCA #neuroimmunology

🪰 How do insects fight infections and remember them? A new Review Article presents an overview of insect immune memory, from antiviral defences to transgenerational immunity, and the unanswered questions.

In their eLife (@elife.bsky.social) review, Adam Bajgar and Gabriela Krejcova examine how immune memory works against viruses and bacteria. They spotlight open questions and propose Drosophila as a model to study innate immune memory and insect vaccination. elifesciences.org/articles/105...

Immune cells don’t just fight infection—they manage the body’s energy too. A Trends in Biochemical Sciences spotlight on Nedbalova et al. shows they release adenosine, signaling other tissues to dial down energy use. sciencedirect.com/science/arti... elifesciences.org/articles/105...

Odsouzena nacisty, zavražděna komunisty. Před 75 lety byla popravena Milada Horáková, absolventka Právnické fakulty Univerzity Karlovy a česká politička. Nikdy nezapomeneme.

🚀 Curious about a PhD in life sciences? Meet EMBL at the Doctoral Insights Symposium — 100% online & free. @embl.org 🔬 Hear from PIs, students & professionals from 20 top PhD programs across Europe! 🔗 www.doctoralinsights.at #docinsights #phdprogram #lifesciences #gradschool #europe #symposium

And to Gabriela Krejčová, for her doctoral work entitled "The role of macrophages in the regulation of systemic metabolism in Drosophila", conducted in the lab of Adam Bajgar at the University of South Bohemia.

Online now - the Spotlight " #SAMcycle and #adenosine at the heart of immune conversations" from Tina Mukherjee and colleagues. #macrophages #infection #immunometabolism #SAMtransmethylation authors.elsevier.com/a/1lHcd3S6Gf...

Julius Lukeš and Jiří Macas Ranked as Top Molecular Biologists in the Czech Republic @czechacademy.bsky.social www.entu.cas.cz/en/news-even...

Adenozin - známá molekula, na kterou se molekulární biologové z Jihočeské univerzity podívali jinou optikou. Výsledek jejich výzkumu zaujal prestižní časopis Science. Na první pohled složitý mechanismus, na druhý už nesmírně zajímavý a univerzální proces, který se děje v každém organismu.

As of today we have three new MSc. owners 🤩 Congratulations!

PhD position in Neuroscience (4-years) on Magnetoreception! Exciting project exploring magnetoreception in insects at the CIMeC @cimecunitrento.bsky.social , University of Trento, Italy Read more: phd.unitn.it/drcimec/116/... and r.unitn.it/en/cimec/nphys contact: [email protected]

Congratulations to all the students who successfuly defended their bachelor thesis. Good luck for the upcoming state exams!

PhD Student Position - Nencki Institute of Experimental Biology

🏅 Nuclear physicist Alice Valkárová and parasitologist Julius Lukeš received honorary medals De scientia et humanitate optime meritis from the Czech Academy of Sciences yesterday, and biochemist Ivo Šafařík was awarded the Jaroslav Heyrovský Medal for Merit in the Chemical Sciences. 1url.cz/MJJY4

🏅Významná jaderná fyzička Alice Valkárová a oceňovaný parazitolog Julius Lukeš získali nejvyšší ocenění Akademie věd ČR De scientia et humanitate optime meritis, uznávaný biochemik Ivo Šafařík medaili Jaroslava Heyrovského za zásluhy v chemických vědách. 1url.cz/MJJY4

Yesterday kicked off the joint Methods of Functional Genomics course by @fscusb.bsky.social and Biology centre ACRS (@czechacademy.bsky.social), featuring expert lecturers from EMBL (@embl.org). Excited for a week of cutting-edge insights and learning!

Excited to see the work of Nedbalova et al. (@elife.bsky.social) featured in a Science dispatch! SAM metabolism and adenosine recycling shown to be central to systemic regulation & immunity. The research highlight from @tomasdolezal.bsky.social lab in @science.org www.science.org/doi/epdf/10....

🤝 IOCB Prague is hiring – we are looking for an outstanding Junior Group Leader in Biosciences to join our vibrant scientific community. See more ► www.uochb.cz/en/open-posi... ⤵️ #openposition #iocbprague #iocb #researchjobs #biosciences

Julius Lukeš (@czechacademy.bsky.social) is the only living scientist from the Czech Republic to become a member of National Academy of Sciences (@nasonline.org) a prestigious US institution. And he does it his own way. Congratulations! (Photo courtesy - Biologické centrum AVČR)

🚨 PhD students in CZ/SK: Don’t miss this! JCMM just opened apps for 2025 #GlaCerHub Research Internships. 🔬 10 months at @ceitec.eu/@vut.cz & #FunGlass 💼 0.3 FTE (full-time equivalent) 📅 Deadline: June 30 Serious research, real experience. Apply now. #JCMM #HorizonEurope

Read more about the finding from our department, that adenosine may be a central player in the mechanism that allows cells to measure their activity and require nutrients. elifesciences.org/digests/1050... @tomasdolezal.bsky.social @elife.bsky.social

💊 Just graduated? EMA’s got 10-month paid traineeships! 🏫 Full-time or mix it with Erasmus+ or Ph.D. 💰 €1,942/month from October to July! 📌 Apply by 6 May: 1url.cz/qJKXZ

Mitochondria, but make it weird. Team of V. Jurčenko and J. Lukeš (@czechacademy.bsky.social) found, that some parasites flipped the switch on how they make energy. In Vickermania, one species runs its mitochondria normally, the other lost key parts—and now runs ATP synthase in reverse. @pnas.org

🌍 Dnes, na Den Země, známe vítěze The Earth prize 2025 – jsou jimi Tomáš Čermák a Anna Podmanická! Gratulujeme🎉 Více (eng)⬇️ www.avcr.cz/en/media/pre...

🐝🧬 How a fruit fly helped us understand animal clocks? Two PhD students from David Dolezel chronobiology group (@czechacademy.bsky.social) recently published in @cp-iscience.bsky.social how different species have tuned their clocks to fit their environments—and sometimes, completely rewired them.

POSTDOC WANTED! Our group is looking for a postdoc to study DNA-protein crosslink repair in the heterochromatin. Apply to work on uncharacterized Arabidopsis proteins identified in the HZE genetic screen. @czechacademy.bsky.social @apecinka.bsky.social @evadt.bsky.social

👉 Apply to the Junior Group Leader position by May 18: imba.science/beagroupleader

🌍 Proč vědci často zabalí kufry a frčí dělat vědu do zahraničí? Je to vůbec k něčemu dobré? ❓Na otázku od iniciativy Czexpats in Science * nám odpoví Radim👇

A kind reminder that the PhD Program application deadline is tomorrow.

How a cell can measure its current activity? How does a privileged cell within an organism demand a supply of nutrients from its environment? Check out a new article from Tomáš Doležal group (@tomasdolezal.bsky.social) in @elife.bsky.social, that adenosine could be at the center of such mechanism.

In @elife.bsky.social: SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response doi.org/10.7554/eLif...

Why humans hunt for mushrooms, and not the other way around? A study by Hassan Hashimi and his team has revealed that the Mgm1 and Opa1 proteins that form mitochondria are not true homologues, as previously thought. These differences may be key to the phenotypes we observe today. 🧬

Diatoms produce up to 20% of the world's oxygen through photosynthesis 🌍✨ Research from Prof. Miroslav Obornik's lab has revealed that the process of Heme biosynthesis, which plays a crucial role in the electron transport chain in mitochondria and plastids, is highly conserved across all eukaryotes.

When the ‘selfish’ brain and the ‘selfish’ immune system clash — a Journal Club by Michaela Fencková www.nature.com/articles/s41...