A man who had severe depression for more than 30 years has "experienced joy" after undergoing bespoke brain stimulation.

For those attending #AAIC25, please consider our session "Improving Clinical Trials for Atypical Alzheimer’s Disease: A Call to Action" on Tuesday July 29th at 2PM!

Our team had worked relentlessly over the past years to make this tool, StateViewer, come to life and available to all neurologists across the Mayo Clinic Entreprise. A great example of ethical AI use to enhance decision-making in real-life clinical scenarios.

Many clinicians are uncomfortable talking about death. We far too often over-treat illness at all cost, losing sight of what truly matters - quality of life. Excellent episode about death, and how to approach this topic with patients and loved ones: freakonomics.com/podcast/does...

📆 Mark your calendars for #AAIC25! Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29! @rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social

After an “update in cognitive & behavioral neurology” talk at AAN, I was asked to chat on the Neurology podcast (also no bsky but my request to change that has been noted!) about some of the content. We focused on plasma biomarkers. Still can’t listen to myself lol. youtu.be/7wWOrZenplQ?...

🚨 Video alert: I was able to share our @mayoclinic.org work on #NeuroAI at #GoogleCloudNext, including how we hope to scale expert interpretation of brain scans to improve dementia care. 🧠 Watch here: youtu.be/lJ1SVeeFWZQ?... #DigitalHealth #AI #endalz

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...

The one case featured across LATE-NC papers appeared to have multiple neuropathologies in the medial temporal lobe at autopsy. Is pure LATE-NC a real thing? This is why we framed this syndrome as a limbic degeneration problem that is agnostic to underlying pathology academic.oup.com/braincomms/a...

If you are at #INS please stop by the non-AD session at 10:45 on Saturday to hear my talk about the clinical syndrome associated with limbic degeneration in old age!

Can't understate the importance of this paper by Deepti Putcha & LEADS... EOAD is not an "earlier" amnestic phenotype. It's a fundamentally different disease. It's about time dysexecutive phenotypes receive the recognition they deserve. alzres.biomedcentral.com/articles/10....

Excited to be chairing a new Stanford faculty search in Neurology. We are looking for MD and MD/PhD physician-scientists who have a strong research program (wet lab or dry lab) and who are also excellent clinicians. Please spread the word. Here's the link to the job posting: lnkd.in/d6REUGfM

K99/R00 proposal is DONE. Can't understate how stressful this process was. Fingers crossed 🤞🏻

Large-scale studies often report findings about what seems to be an unusual "young-onset, aggressive" subtype of AD. Clinically we call this dysexecutive AD. We clearly define the distinct clinical and biological features of this AD variant here --> academic.oup.com/braincomms/a...

Excited to collaborate on this NIH-funded project on rapidly progressive dementias.

Great Friday ahead 🫠

I am officially seeking a postdoc to work with us on software development for de-facing and PET quantification. Please pass along to any eligible candidates you may know. jobs.mayoclinic.org/job/rocheste...

One of many ways to usefully prognosticate for patients using FDG-PET: www.sciencedirect.com/science/arti...

Merry Christmas from me and the #1 packers fan

Been asked to review like 5 papers this week, right before PTO and Holidays. Am I alone? Ugh.

Check out our new paper on the identification of ultra-rapid progressive dementia (with case studies & review): link.springer.com/article/10.1...

mayomagazine.mayoclinic.org/2024/12/ai-a...

Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP doi.org/10.1007/s004...

Finished a first draft of my K99 😮‍💨. Not at the finish line yet, but looking forward to a well-deserved rest over the Thanksgiving holiday.

I‘m so proud of this team effort, thanks Nick for sharing it here! 😊

Big chunk of our work in the past years!

So much of Behavioral Neurology’s knowledge can be visualized through a data-driven, self-assembled graph of FDG-PET metabolic patterns across neurodegenerative and non-degenerative clinical diagnoses. 📊✨ #Neurology #FDGPET #BrainImaging #DataScience #Neurodegeneration #endalz

Hi #SciSky👋🏾 My name is Desmond Warren & an aspiring clinical neuropsychologist! My interests include TBI, cognitive aging, & #neuroimaging! I've started a Clinical Neuropsychology Starter Pack & if you would like to be included, please let me know! #NeuropsychSky #PsychSky go.bsky.app/8fgyJiS

📢 Reminder: I'll be taking PhD students through Boston University's Clinical Psych program in the upcoming cycle! 👩‍🎓🎓Deadline: Dec 1st. Candidates with interests in multicultural neuropsych, neuroimaging & aging are encouraged to apply!🧠 Bilingual skills in Spanish or Portuguese are a plus🌟#Boston

Fully agree. Got hired at Mayo through Twitter - this led me to pursuing my dream job, getting married, and many other pivotal moments of my life. And I've made so many friends there. Twitter has been good to me. Not easy to say farewell.

I have deleted all of my tweets from X using tweetdelete.net. Well worth the $3.99 fee for one month to remove all 9,609 of them, and super easy to use.

Fresh from the other offering. Can we make this a great forum for science and fun? Let’s go @bsky.app!!

Hello world. Happy to be on here

🧠 Neuroscientist, just migrating to @bsky.app 🦋! Here to share science about neurodegeneration, astrocytes, and all things about neuroscience! More about me and my lab 👉 zimmer-lab.org 👉 Let’s connect!

Nature is healing

I have a couple of open postdoctoral position in my lab, in Epidemiology of Neurologic diseases, in Alzheimer's disease and also in Migraine. recruit.ap.uci.edu/JPF08741

Signing my first note as Nick Corriveau-Lecavalier, Ph.D., L.P. 🧑‍⚕️

In the midst of this X migration, let me re-introduce myself: I am a clinical neuropsychology fellow at Mayo Clinic interested in degenerative dementia (especially atypical AD), cognition, an AI. Canadian-born and trained 🍁, so also big fan of hockey and maple syrup!

With many colleagues from Mayo and the Prion Disease Pathology Surveillance Center, we found that FDG-PET can inform survival time in prion disease. See the paper in ACTN below: wiley.scienceconnect.io/api/oauth/au...

Check out our new review on cerebral hyperactivation in #Alzheimer's disease. Just out in Brain Communications! academic.oup.com/braincomms/a...

Our latest paper, describing the history and procedures for de-facing in ADNI, is now published in Alz & Dem: alz-journals.onlinelibrary.wiley.com/doi/full/10.... This is part of a larger special issue on ADNI.

New paper! A universal pattern of brain wave frequencies. They are slower in deep cortical layers and faster in superficial layers. When something is this ubiquitous, you know it is doing something important. picower.mit.edu/news/study-r...

I'm happy to share a paper for the first time on this platform! We proposed clinical criteria for a limbic-predominant amnestic neurogenerative syndrome highly associated with TDP-43. Please share widely! www.medrxiv.org/content/10.1...

First time asking my admin assistant to set up a meeting for me. I feel like I'm on the top of the world.

If you are thinking of plotting distributions and/or confidence intervals, I highly recommend you check out the ggdist package by @mjskay.com #rstats #ggdist github.com/mjskay/ggdist/

A picture of me and my tired girl. This should get me the right type of followers.