Ethan Rossi from @pittophthalmology.bsky.social on imaging multimodal cellular imaging. Ethan covered a lot of ground as the second of our 2026 Boynton Seminar series @cvsuor.bsky.social @flaumeye.bsky.social @urochester.bsky.social

#FluorescenceFriday This microscopic🔬 object is a specialized immune cell (microglia) that resides in your retina👁️ and is responsible for damage control and refinement of neural circuits. GFP labeled @urneuroscience.bsky.social @urochestersmd.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social

🔬Our team @urochestersmd.bsky.social is building a 📹camera to image through layers of the living eye👁️. By changing focus, we reject out-of-focus light to image 3 layers of retinal vessels @cvsuor.bsky.social @uofrbme.bsky.social @urneuroscience.bsky.social iovs.arvojournals.org/article.aspx...

🌈Chronochromatogram 🌈J Schallek Art-of-Science submission #ROC starfield + Matlab code produces my: "Chronochromatogram" Chrono=Time Chromato=Color Gramma=Drawing Drawing time in color @urochester.bsky.social @thisisroc.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social @cvsuor.bsky.social

🌈Chronochromatogram 🌈J Schallek Art-of-Science submission #ROC starfield + Matlab code produces my: "Chronochromatogram" Chrono=Time Chromato=Color Gramma=Drawing Drawing time in color @urochester.bsky.social @thisisroc.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social @cvsuor.bsky.social

Alien to land; at home in the sea. This beautiful creature is a blood-belly comb jelly. Jaw dropping display at the Monterey Bay Aquarium.

The Heart❤️ connected to the Eye👁️ Our 2019 study shows single blood cells imaged in eye report out the pulsatile waveform of heart output @flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social doi.org/10.7554/eLif...

Grant Writing @ 4am: current vibe

These lads all born on this day, Feb 12th (...One still working on his beard 🧔) @flaumeye.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social @urochester.bsky.social

Neutrophils are white blood cells that circulate in our blood. When they reach capillaries, they compress & fill these vessels. Derek Power et al via:👇👇 doi.org/10.7554/eLif... @urneuroscience.bsky.social @flaumeye.bsky.social @urochestersmd.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social

Good news indeed. Michael's advocacy for the importance of Eye research dovetail with his diplomacy in challenging environments. Lets keep this going...

Bathed in moonlight Snow sparkles bright No need for summer nights... #ROCTopShots ☃️ #roc #ThisisRoc @flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social

Happy Holidays From the Advanced Retinal Imaging Alliance! 2025 Holiday party after @arvoinfo.bsky.social abstract submissions! @urneuroscience.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @flaumeye.bsky.social

Happy Holidays From the Advanced Retinal Imaging Alliance! 2025 @urneuroscience.bsky.social @uofrbme.bsky.social @cvsuor.bsky.social

⍺SMA- Collagen IV+ Interpericyte Tunneling Nanotubes in 👁️Macular vasculature decrease in #T2D diabetes patients (w/o retinopathy) 6 Case + 8 Ctrl No overt change in Macular Capillary density, #Pericyte density or Pericytic TNT length/diameter #Diabetologia 2025 link.springer.com/article/10.1...

Fire and ice... Beautiful colors of the light engine that drives our adaptive optics cameras to image the living retina.🔬👁️ @cvsuor.bsky.social @uofrbme.bsky.social @flaumeye.bsky.social @urneuroscience.bsky.social

@arvoinfo.bsky.social members, remember to cast your vote for the 2025 ARVO Scientific Image Contest! Review the fabulous finalists and select your favorite by Nov. 14: https://bit.ly/4mNNbq8

#FluorescenceFriday @arvoinfo.bsky.social scientific image contest (voting link below) 👇👁️👇: microglia imaged in the retina, color-coded for depth ARVO Image Contest www.arvo.org/news/scienti... @flaumeye.bsky.social @cvsuor.bsky.social @urochestersmd.bsky.social @urneuroscience.bsky.social

This is the way... Happy Halloween from @cvsuor.bsky.social @flaumeye.bsky.social @urochester.bsky.social @urneuroscience.bsky.social @marcoslabur.bsky.social @uofrbme.bsky.social

happening tomorrow! Full day covering latest applications and advances in the Center for Visual Science @cvsuor.bsky.social @flaumeye.bsky.social @urochester.bsky.social

#FluorescenceFriday Watch to the end! Immune cells in the retina remain flat until damage is detected. Cells change their shape and dive deep in response to damage (pink cell) @cvsuor.bsky.social @urochester.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social elifesciences.org/articles/98662

My boss/mentor Teresa Puthussery won a MacArthur genius grant today! She shares the award with Oakland novelist Tommy Orange (read There There! It's awesome!), resource recovery chemist William Tarpeh, and 22 others. Congratulations Teresa! www.macfound.org/fellows/clas...

Austin Roorda @roordalab.bsky.social delivering the richly deserved Boynton Lecture @optica-fvm.bsky.social @optica.org A tremendous journey with an incredible cast of characters that brought the world high resolution retinal imaging, Oz Vision and olo

Congratulations to Susana Marcos @marcoslabur.bsky.social receiving the Tillyer Award @optica.org Fall Vision Meeting in #minneapolis Introduced by Steve Burns, her mentor from postdoctoral days. @cvsuor.bsky.social @flaumeye.bsky.social @urochestersmd.bsky.social

Our next researcher at the Optica meeting is Jesse B. Schallek, Ph.D., who along with his lab, studies how blood flows through the vessels in the retina. They aim to understand how changes in this neural-vascular network contribute to retinal diseases and vision loss.

Microglia (white/green) are immune cells that live in specific layers in the retina. In response to injury, they migrate into location of damage. doi.org/10.7554/eLif... @flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social

#cvstoday 3:00 pm, Helen Wood Hall SON Auditorium, 1W-304 Knill Lecture: Daniel Wolpert, Columbia University Computational principles underlying the learning of sensorimotor repertoires There will be a reception immediately following the lecture in Helen Wood Hall 1W-300.

#FluorescenceFriday Strand and branch pericytes surround the vessels of the retina👁️🔬 color=depth @flaumeye.bsky.social @urneuroscience.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social

Meet Dr. Sara Patterson, a researcher at Flaum who is participating in the Emerging Vision Scientist Program. Her lab studies how the eye communicates with the brain. This groundbreaking work is paving the way for new treatments to restore vision. #VisionResearch #VisionRestoration #EyeHealth

Thank you, Rep. Morelle, for visiting the Flaum Eye Institute to discuss and see firsthand how NEI-funded research improves patient care and drives innovation in ophthalmology. We are grateful for your support and recognition of the important role federally funded research plays.

She did it! Very proud to announce: the newly minted Dr. Fei Shang, PhD in Neuroscience. Vascular insights... to what gives us sight! @urneuroscience.bsky.social @flaumeye.bsky.social @cvsuor.bsky.social @urmed.bsky.social

🧠Today🔬 PhD Thesis defense by Schallek Lab student Fei Shang! 1pm K-207 conference room, URMC. Come to learn about how vessels nourish the eye.👁️ @cvsuor.bsky.social @urmed.bsky.social @urneuroscience.bsky.social @flaumeye.bsky.social

We’re thrilled to share that our very own Matt Cavanaugh has been chosen for the Emerging Vision Scientist Program, where he will advocate for congressional support of vision research. We’re so proud of all he has accomplished so far and for his commitment to advancing vision care!

#FluorescenceFriday NEUTROPHILS are rare immune cells flowing within trillions of blood cells of the body. Using #AdaptiveOptics cameras, we directly image fluorescent neutrophils in the vessels of the eye doi.org/10.7554/eLif... @flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social

You don't have to be a scientist to think lasers are cool😎 But the 👨‍🔬 in @schalleklab.bsky.social have cool lasers 👇Lab mngr Derek Power led research using the adaptive optics camera, a laser engine, & found how immune cells in the eye respond differently when the retina is injured 👉 bit.ly/4fB7y7P

Love this... Here's a chunk of mine in peer-reviewed form 😉 @cvsuor.bsky.social @flaumeye.bsky.social

EXCITATION At the heart of our adaptive optics camera is a laser engine. A beam of light scans the retina to image the eye with single cell resolution. @cvsuor.bsky.social #FluorescenceFriday #AOSLO @urochester.bsky.social @urochestersmd.bsky.social @flaumeye.bsky.social @urneuroscience.bsky.social

👇3D look at adaptive optics imaging table in the @schalleklab.bsky.social This tool allowed researchers to discover that microglia, not neutrophils, a type of white blood cells, respond to photoreceptor damage in the retina Read more: bit.ly/4mmmPvx #URochesterResearch @flaumeye.bsky.social

✨Our newest eLife paper is out!✨ 👉 elifesciences.org/articles/98662 When retinal cells die, who cleans up? Non-invasive imaging shows microglia👇 rush to help but don’t recruit neutrophils from the bloodstream. @urneuroscience.bsky.social @cvsuor.bsky.social @elife.bsky.social #FluorescenceFriday

#URochesterResearch by @schalleklab found that when photoreceptor cells in the retina are damaged, the brain’s immune cells respond, and neutrophils are not recruited to help despite passing through nearby blood vessels via eLife 👉 elifesciences.org/articles/98662 @cvsuor.bsky.social

Thrilled to have been selected for the @cvsuor.bsky.social pilot award with additional support from @flaumeye.bsky.social. Our collaboration with Wojtovich lab will study mitochondria survival and anatomy in the diabetic retina. @urochester.bsky.social @urochestersmd.bsky.social

Dynamic Sholl analysis is a way to characterize the complexity cell process remodeling over time. Here SchallekLab is using it to show microglia dynamism in the living eye using #adaptiveoptics #Optica @cvsuor.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social bit.ly/4kMNErh

💡FIREFLIES💡 were alive last night. Long-exposure reveals secrets of their patterning. Bioluminescence is one of the most captivating forms of signaling for life on our planet. @uofrbme.bsky.social @flaumeye.bsky.social @cvsuor.bsky.social @urochester.bsky.social @thisisroc.bsky.social

The #AdaptiveOptics in the #eye Course kicked off yesterday @cvsuor.bsky.social with 6 intensive hours on #AO for #RetinalImaging & #VisualSimulation w @schalleklab.bsky.social & @marcoslabur.bsky.social. More today with out engineers on #HowtoBuild on; #RochesterOptics @urengineering.bsky.social

Time-lapse of the stars above Rochester. In times when it seems like much is falling apart... I find it useful to re-orient and look upward. Take a moment to remember, the world spins on. @cvsuor.bsky.social @urochestersmd.bsky.social @flaumeye.bsky.social @urneuroscience.bsky.social

22degree Moon Halo A vivid shot from Feb Physical basis unknown. Optical theories posit that hexagonal crystals with refractive index n=1.309 may deviate moonbeams to create a 22deg ring via Snell's Law AKA: moon ring winter halo @cvsuor.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social

Jupiter Bowl: as an outlet for creativity and deepen my roots in woodworking, I began wood turning this past winter. This one -a spalted maple- has a striking resemblance to the stormy skies of Jupiter @cvsuor.bsky.social @urneuroscience.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social

Vessels of the brain🧠 are enveloped by alpha-smooth muscle actin that have a rubber-band like appearance. These bands contract or dilate based on the neural load. @urneuroscience.bsky.social @cvsuor.bsky.social @flaumeye.bsky.social @uofrbme.bsky.social #FluorescenceFriday

In an ocean of CFP... be the GFP 🧪🔬⚗️ #FluorescenceFriday #ARVO2025 edition @cvsuor.bsky.social @urneuroscience.bsky.social @arvoinfo.bsky.social @flaumeye.bsky.social

Bittersweet: last night @arvoinfo.bsky.social #ARVO2025 #SaltLakeCity @cvsuor.bsky.social @flaumeye.bsky.social