🌌 A common question we get is, “Why perform research in space?” 🤔 In the latest @scifri.bsky.social episode, our Catriona Jamieson, MD, PhD, and Meenal Datta, PhD, explore numerous reasons — including the tendency of space to activate the “dark genome.” 🎧: bit.ly/3RoqLl0 #cancer #medicine #space

Our reGEN Podcast 🎙️ with Jonathan Thomas, PhD, JD, President and CEO of @cirmnews.bsky.social reviews the Alpha Clinic network and patient-focused novel therapeutics, clinical trials and gene therapies. Watch here bit.ly/4ffhe9K or listen 🎧 where you find your podcasts. #stemcells #genetherapy

👩‍🚀 Call us #space cadets in the best of ways — heads in the clouds, eyes set on the stars and preparing for our 19th and 20th research project launches, aboard SpaceX CRS-34, 4 pm PDT May 12 at Cape Canaveral Space Force Station. 🛰️ Stay tuned for more exciting news on the launch! #nationalspaceday

When you support SSCI on Triton Giving Day & every day, you help us develop & deliver cutting-edge treatments to the patients who need them most, with conditions like HIV/AIDS, Parkinson's, epilepsy, MS, type 1 diabetes, cancer & more. Donate: bit.ly/429duzb. #ucsandiego

bit.ly/3R7EJYh Tune in for our reGEN Podcast 🎙️ conversation with Tannishtha Reya, PhD, who is credited with creating the term “cancer stem cells.” She has created novel approaches to map normal stem cell behavior within living organisms. Listen 🎧 where you find your podcasts. #MedTwitter #stemcells

A $13M award from @cirmnews.bsky.social is funding groundbreaking #regenerativemedicine research led by @geneyeo.bsky.social and team to tackle “RNA pollution”🧬 as a root cause of neurodegeneration to protect the aging brain 🧠. Learn more @: bit.ly/41VgKOv. H/t @salkinstitute.bsky.social

Looking for a quick pick-me-up? 😄 Check out this 20-min episode of the Cell & Gene podcast. 🧬 It features SSCI Director Catriona Jamieson, MD, PhD, who discusses exciting advancements in #cancer treatment that she believes will be available in 1-2 years: bit.ly/4vI2t5h

SSCI Director Catriona Jamieson, MD, PhD, & Alysson Muotri, PhD, director of our ISSCOR Center, are featured in this article about the innovative #space research being performed at @ucsandiego.bsky.social: bit.ly/3On9tUi. @ucsdmedschool.bsky.social @scrippsocean.bsky.social

🔬 SSCI's computational biologist Ludmil Alexandrov, PhD, recently discovered that some E. coli infections lead to genetic mutations often found in early-onset colorectal cancers. 🦠 He's creating a stool-based test to ID young people at high risk. More: bit.ly/4t5qD86. 👏 @ucsdmedschool.bsky.social

Our Karen Christman, PhD, a visiting fellow of the Charité Foundation at @mdc-berlin.bsky.social, will spend three months this summer in Berlin, Germany, partnering with its researchers. Read more about her pioneering work in biomaterials: bit.ly/48hLD32. H/t @christmanlab.bsky.social

🚀 Our Integrated Space Stem Cell Orbital Research Center has sent 18 sets of experiments to the International Space Station so far. 🛰️ Why perform research in #space? Director Catriona Jamieson, MD, PhD, explains in an essay in @thelancetoncol.bsky.social: bit.ly/4bVBN9n. 👩‍🚀 @ucsdmedschool.bsky.social

bit.ly/3NO9OiN 🎙️ Tune in to our reGEN Podcast with Leo D. Wang, MD, PhD - City of Hope - for insights on the @cirmnews.bsky.social Alpha Clinic network & breakthroughs in pediatric #cancer; from engineered cell therapies to “living medicines,” advancing care for aggressive cancers. #stemcells

🚀 March 6 was a busy day for us, as our Catriona Jamieson, MD, PhD, chaired a daylong RNA, stem cell- & gene-based therapies track at Precision Medicine World Conference, bringing a space-health perspective. Joining her: Alexis Komor, PhD; @geneyeo.bsky.social; & Alysson Muotri, PhD. bit.ly/4sKgSw1

🎉 We’re celebrating Maya Gosztyla, PhD, a '24 @ucsdhealth.bsky.social grad and finalist for the Chancellor’s Innovation Award in the student/alumni innovator of the year category for founding BrainStorm Therapeutics. 🥳 She got her start in the lab of SSCI's @geneyeo.bsky.social. bit.ly/4maLKmU

bit.ly/4dCaVwg 🎧 Watch or listen to our latest reGEN podcast interview with Dana Levin, MD, MPH, Vast's director of space medicine, as we discuss medical resilience for astronauts living and working in space for extended periods of time. Watch on YouTube or listen where you find your podcasts.

🚀 Thanks to all who joined us for our 4th Global Astrobiotech Hub event earlier this month, where we celebrated 18 launches of research projects to the International Space Station — and counting! Read more about the event: bit.ly/4lVOd4j. #stemcellscience #regenerativemedicine #spacemedicine

🎉 SSCI directors had a blast sharing their work at @sxsw.com last week. Alysson Muotri, PhD, presented on diversity, Neanderthal DNA & the dark genome. And @geneyeo.bsky.social, PhD, & Alexis Komor, PhD, discussed how #AI is ushering in an era of precision #genetics. 🧬 See you next year in Austin! 🤞

SSCI’s Alexis Komor, PhD, and colleagues created an improved version of a gene base editor with higher efficiency minimizing unwanted bystander edits - enhancing 🧬 gene editing & disease modeling for treating genetic disorders. Learn more @ bit.ly/4sms8hU. @natbiotech.nature.com

Nearly 40% of Americans have metabolic syndrome, which carries w/it the risk of liver fibrosis (MASH). Treatment options are limited but expanding, thanks to the work of SSCI's Tatiana Kisseleva, MD, PhD; Gene Yeo, PhD; & colleagues. More on their work: bit.ly/4bsWDvs. H/t @sbpdiscovery.bsky.social

How will AI reshape public health and decision-making? In our latest 🎙️ podcast, @bruceylee.bsky.social, MD, MBA, shares insights on the intersection of AI, systems modeling and health communication systems. 🎧 Watch here: bit.ly/4sDUAeI #AI #Health #StemCells

🎉 A patient with Pitt-Hopkins syndrome has received an investigational, 1st-in-human gene therapy, thanks to the lab of SSCI's Alysson Muotri, PhD. It's the first drug developed using brain organoids — and not animal models — to reach clinical trial. Cheers to hope! 🥂 H/t @ucsdmedschool.bsky.social

💡 Sanford Stem Cell Innovation Center Deputy Director Alexis Komor, PhD, was honored Friday w/the Precision Medicine World Conference Luminary Award for co-inventing #CRISPR base editing. 🌟 SSCI Director Catriona Jamieson, MD, PhD, received the award in 2024, for advancing cancer-stem-cell biology.

SSCI Director Catriona Jamieson, MD, PhD, recently attended the @ucsdmedschool.bsky.social Summer Research Symposium to support a med student she mentored. “It’s essential for students to conduct research, particularly medical students who will someday see patients,” she said: bit.ly/4rjKDCd #cancer

Congratulations to SSCI’s Ludmil Alexandrov, PhD, who will lead Team CAUSE, awarded $25M from Cancer Grand Challenges, to decode mutational 🧬 DNA signatures or “fingerprints” that may reveal how cancer begins, informing potential treatments. 🔬 Learn more bit.ly/4r7if63. #Cancer #StemCells #DNA

🦓 This #RareDiseaseDay, we’re proud to shine the spotlight on 5 rare disorders & 4 researchers turning hope into reality for patients w/CPS1D, T-cell acute lymphoblastic leukemia, Rett syndrome, Pitt-Hopkins syndrome & ALS. More: bit.ly/3N8UqNk. H/t @rarediseaseday.bsky.social @nucdf.bsky.social

🚀 Catch up on the latest advances in #space related #stemcell #science and #regenerativemedicine at our Global Astrobiotechnology Hub event THIS MONDAY, March 2, 2-6 p.m. PT. Complimentary online tix are still available at bit.ly/4bhqpol. 🧫

🚀 Just dropped, our new podcast 🎙️ with Alysson Muotri, PhD. We explore the intersection of #stemcells, medicinal Amazon Rainforest discoveries, Neanderthal DNA, space-based research and disease remodeling - all reshaping how we understand human health. 🧬 Watch here bit.ly/46tGJiF 🎧

🔬 #genetherapy holds incredible promise but carries the risks of immune response and toxicity. To combat this, SSCI's Alexis Komor, PhD, and team developed a workflow that allows scientists to more effectively deliver less DNA. Read more at bit.ly/46d1f72. H/t @natureportfolio.nature.com 🧬

🚀 Catch up on the latest advances in #space related #stemcell #science and #regenerativemedicine at our Global Astrobiotechnology Hub Event on Monday, March 2, 2-6 p.m. PT. Complimentary online tix are still available at bit.ly/4bhqpol. 🧫

💔 The heart’s ability to heal itself is limited. After a heart attack, scar tissue prevents a fatal rupture. But it can't contract or conduct electrical signals, significantly raising the risk of heart failure. More on an innovative solution from SSCI’s Karen Christman, PhD, here: bit.ly/3MMwuze. 💓

SSCI’s @geneyeo.bsky.social and collaborators developed Ribo-STAMP, a technology that tracks protein production in single brain cells. Their @nature.com study maps the brain’s “translatome,” revealing differences in memory neurons & new clues to disorders like autism. Learn more @ bit.ly/3MkKQ9X

Can the hivemind use Carol's frozen eggs to assimilate her? Our @signerlab.bsky.social separates stem cell fact from fiction in the remarkably plausible Apple TV blockbuster Pluribus. bit.ly/4rUc1az H/t @ucsandiego.bsky.social

Tune in to learn about innovative stem cell biology trends in our latest reGEN Podcast 🎙️ conversation with Tiffani Manolis from @thermofishersci.bsky.social. Watch here bit.ly/3MApmFZ or listen where you find your podcasts.

bit.ly/3M54NRS Learn about innovative and groundbreaking research with RNA, gene editing and stem cells in our latest reGEN Podcast conversation featuring @geneyeo.bsky.social, PhD, MBA. Watch here or listen where you find your podcasts. #stemcells #RNA #sciencepodcast

🧫 Can stem cell research unlock the secrets to living longer + healthier? 📺 Watch “A Closer Look at Stem Cells and Human Longevity” w/our @signerlab.bsky.social + Shiri Gur-Cohen on UCTV to find out — a must-watch for 2026, according to the channel. Video @ bit.ly/49mrgCQ; list @ bit.ly/45hBj9U.

Get a behind the scenes look at stem cell and related clinical trials at our @cirmnews.bsky.social Alpha Clinic and Sanford Stem Cell Clinical Center with Julissa Gonzalez, MS, in our latest reGEN Podcast episode. View here or listen where you find your podcasts: bit.ly/49y2EY1

Triple-negative breast #cancer is aggressive & difficult to treat. Thanks to the work of our @geneyeo.bsky.social, PhD, MBA, a new potential therapeutic target has been ID'ed: the protein PUF60. 🙌 Knocking it down dealt a substantial blow to cancer cells — but not healthy ones. More @ bit.ly/4jIXRq6

🧬 The research of our Ludmil Alexandrov, PhD, is highlighted in a recent @businessinsider.com piece on rising rates of aggressive colon #cancer in otherwise healthy young adults. One potential contributor, according to Alexandrov: childhood E. coli infection. 🦠 Read the full piece @ bit.ly/49JBqxp.

🙌 A $7.4 million California Institute for Regenerative Medicine grant awarded to SSCI expert Stephanie Cherqui, PhD, and team will ready a revolutionary new treatment — a stem cell-based gene therapy for Friedreich’s ataxia — for clinical trial. 🎉 More: bit.ly/4jw1qiY. H/t @cirmnews.bsky.social

🦠 Last year saw fascinating developments in cell biology. 👀 Among those capturing the most public interest at The Scientist: SSCI Director Catriona Jamieson’s research on stem cell aging in space. 🛰️ Read more about her impactful work at bit.ly/4qamL4n. 🧫

🎧 Tune in for our reGEN Podcast episode with Marisa Korody, PhD, as we discuss conservation genetics at the @sandiegozoo.bsky.social. Her team's groundbreaking work uses #stemcells to help save the northern white rhino 🦏 from extinction. Watch bit.ly/4pUe7H2 or listen where you get your podcasts.

🌍 International research collaborations help avoid duplication of effort, speed progress and spread new knowledge. Our recent Hertzberg-Schechter Stem Cell Workshop did just that, uniting U.S. experts with those from Israel’s Weizmann Institute of Science. More @ bit.ly/4p5uEGV. 🔬

Best. Present. Ever! 🎁 A toddler born with a deadly rare genetic disorder who received a personalized gene therapy earlier this year thanks to our Alexis Komor, PhD, et al., is home from the hospital and walking — just in time for the holidays! 🥳

🔬 Chromosome-shattering is one reason some #cancer cells evolve rapidly & resist treatment. For 15 years, the cause was unknown. Our Frank Furnari, PhD, & Ludmil Alexandrov, PhD, as well as other @ucsandiego.bsky.social researchers, solve the mystery this month in @science.org: bit.ly/4paoNA1

🎉 Did you know? SSCI’s Alysson Muotri & Stephanie Cherqui co-direct the Gene Therapy Initiative at @ucsandiego.bsky.social, which has helped fund the work of our Dan Kaufman & @geneyeo.bsky.social. It all started 2 decades ago w/the birthday wish of a girl w/a rare disorder. 🎂 More: bit.ly/4aswL3X

👏 We're proud to announce that SSCI’s Ludmil B. Alexandrov and team are recipients of Curebound's $1 Million Cure Prize for their work to detect pancreatic #cancer early. Major congrats to @signerlab.bsky.social and Frank Furnari, too, for receiving Discovery grants. More @ bit.ly/44RFedp

👩‍🚀 What are the health effects of space on astronauts? Our Catriona Jamieson, MD, PhD, sheds light on the topic in a new @cp-cellstemcell.bsky.social article. Her work — the 1st comprehensive study of stem cell health in astronauts — provides answers NASA Twins couldn't: bit.ly/3KsuyLe

Alysson Muotri, PhD, was recently featured in The Telegraph: “Space can accelerate the senescence of human brain cells, compressing the research time,” and he thinks it's “very likely” that a cure for motor neurone disease may be found by research in space bit.ly/43ALEgg

The 2025 UC San Diego Sanford Stem Cell Institute symposium brought together over 700 extraordinary scientists, clinicians, innovators and patients united by a shared vision: harnessing the power of stem cells to heal, regenerate and transform medicine. bit.ly/4hKs9rn

The 2025 @ucsdstemcells.bsky.social symposium at @UCSanDiego.bsky.social brought together an extraordinary group of #scientists, #clinicians, #innovators and #patients united by a shared vision: harnessing the power of #stemcells to heal, regenerate and transform #medicine. buff.ly/mrK9GM1