Still don't have bluesky in my state, so VPNing in. I'd like to blame that extra activation energy as my reason 4 being absent, but the bigger culprit has been grant writing. Several foundation grants (and a couple federal just in case the government ever functions again)

Needs a bit of work, but not bad for our first attempt on the new lightsheet microscope... #FluorescenceFriday (again on a Saturday 🙃)

Again a bit late for #FluorescenceFriday, but here's a decent image of anterior crista from a rat inner ear. The long projections in magenta are stereocilia, which, on crista hair cells, are likely the longest microvilli made by any cells in mammals. They help with balance, movement, and vision.

A good article... www.americanscientist.org/article/%E2%... I think there's much more to it than scientists needing to communicate better, but these points are definitely valid and so I will try to communicate them by sharing...

What's the Vegas line on Ghislaine Maxwell getting a pardon; then naming a bunch of names (which'll be touted as the Epstein files), and then only drumpf's enemies being named? I know a trifecta should be long odds, but I feel like I should have to pay out at least 5:1 if this doesn't happen.

Superman movie is out. Haven't gotten a chance to see it yet, but it did inspire me to look at some of my collection which is usually hidden in boxes around the house, including this gem...

Just a dinosaur enjoying the sunrise.

Here is a good link to watch the meeting and COMMENT www.fda.gov/news-events/...

We live in such exciting times! Ai performing surgery! I mean my insurance company's ai will never approve it, but it's so fun to think about.

A favorite poster of mine, originally from 1949, but seems timely as there seems to be some questions about superman online these days...

Hydrangeas looking pretty good in the back garden...likely need more water and more acid.

Got some new books for bedtime reading with the kids. I believe tonight we start book 2 of Fart Quest (having already rapaciously devoured book 1 in this soon to be literary classic series)

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

I feel this so much all the time...

Wish I was in the DC area to attend this... nasawatch.com/congress/con...

"a history of repeated injuries and usurpations, all having in direct object the establishment of an absolute Tyranny over these States. To prove this, let Facts be submitted to a candid world. He has refused his Assent to Laws, the most wholesome and necessary for the public good."

I really don't know how to respond to this. I think I've written and then deleted at least a dozen posts, but I guess the only thing to say is WTF?

Republicans: we need politicians who'll run government like a business!! Mamdani: if elected, NYC will start a small chain of grocery stores Republicans: Terrorist! Deport him!!!

From my back garden...

Got an old Leica microscope working again in the lab (with a $50 objective bought on ebay). Can you tell which image is from the $50 objective (and $16,000 camera) versus the one taken on the $600,000 confocal microscope?

Best mascot ever!

Mr. Musk, I believe this will be MUCH more effective if YOU call my senator and representative. Thx.

Senator Ossoff speaking the truth. We need real action

Just ordered a refurbished computer with a mid level gpu. Going to do some machine learning at home. And if that fails then maybe my kids will use it for video games.

A day late for #FluorescenceFriday but here is a video from what we've been working on lately, looking at synapses and axonal "coats" (orange). The presynaptic components are teal and the postsynaptic glutamate receptors are shown in white.

To anyone questioning why we still need DEI programs in 2025, may I remind you that several states STILL have a paid holiday TODAY for their workers for confederate memorial day en.wikipedia.org/wiki/Confede...

Tennis Balls xkcd.com/3080

I know I usually post "aerial" views, but here's a side view of auditory cells from a section of a mouse temporal bone. The hair cells are labeled (green) with a Myo7a antibody and the nuclei of inner hair cells and supporting cells (magenta) are labeled with a GATA3 antibody. #FluorescenceFriday

Well, I admit that I disagree with the new health secretary on many things, but on removing artificial dyes from food, we are in agreement, and since this is likely to be the only "win" I expect to see healthpolicywise for a while, then let's celebrate it www.cnbc.com/2025/04/22/f...

Putting Easter chocolate to good use by combining it with soy, chilis, salt and spices on an 8lb brisket.

Been extra busy lately. More pics will be forthcoming. But here is one for #FluorescenceFriday (more auditory hair cells in mouse cochlea but also inner & outer sulcus & spiral limbus)

I am 6'3, 224 lbs (well 219 @the moment). The other day, I was depressed to discover that means I must have the same physique as POTUS. Today I am feeling extra flattered... www.latintimes.com/chatgpt-decl...

Howie Roseman says the #Eagles won't even scout players who have ever been violent with women: “I won’t even watch them. I don't even want to talk. I can't go 'He’s really good, he did it 10 years ago and he learned from it.” It just doesn't work for us." #FlyEaglesFly (🎥: The McShay Show)

This.

Big win for the First Amendment and journalism today in Mississippi as a judge dismissed a former public official's defamation lawsuit over reporting that went on to win a Pulitzer Prize.

At a conference in Alabama, and happy for the moment that tariff induced inflation hasn't hit yet. Got a salad with a half pound ea of salmon, shrimp, and lump crabmeat for $22. I'd show a picture but I ate it too fast

Four critically endangered Galapagos tortoises have hatched for the first time in the Philadelphia Zoo’s 150-year history. They were born to the ~100-year-old Western Santa Cruz Galapagos tortoise known as “Mommy,” who is the zoo’s oldest resident. 🧪🐢 www.independent.co.uk/news/science...

I mean if ur linking 'em to fossil fuels, yeah it's a bit indirect, but AK, TN, MS, & LA used to be covered in old growth forests, which were razed, & replaced with farms & pine plantations & now all the pine is being cut down for paper & you have hot, flat land perfect to feed energy to tornadoes.

Yes, all one has to do is look at the last 20 years of Supreme Court rulings to see how far to the left the judiciary has moved. Sigh. Do these people ever say anything that is true?

Saddened by the loss of Val Kilmer. Also angered by the headlines "Batman Forever star..." seriously? The Doors, Real Genius, Top Gun, The Saint, Top Secret, TOMBSTONE!!! Y'all are doing this man dirty. Show some respect for crying out loud.

Most people are unaware that in GOOD times researchers live in a "climate of fear". You've a better chance becoming a NAVY SEAL than becoming a faculty member at an R1 academic research institution. THEN your apps must be top 5-10 percentile to get funded. Now is just SHEER DISGUST and Despondency

Thank you Senator Cory Booker. This guy truly cares about the people he represents.

Wow! Just wow. I have a hard time working until midnight these days. Very impressive.

Destroying the country to benefit individual broligarchs

Tips For Keeping Backyard Chickens theonion.com/tips-fo...

This is so blindingly obvious. But I'm still glad people within the world of Trumpism are willing to say it. And not just national security but economic/dynamism and prosperity which of course is the sine qua non, the necessary condition of national power.

I learned a lot from this article…yikes😱 drilled.media/news/network...