Very excited to be off to the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference on 19th-20th November! Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️ Please do shout if you are going along - would be great to say hello 👋 #FFHSC25

A new #systematicreview and #networkmetaanalysis shows that antidepressants differ markedly in their physiological effects, with substantial differences in parameters such as weight, cholesterol, heart rate, blood pressure www.thelancet.com/journals/lan... @thelancet.com #OA #depression #NMA

Happy Ada Lovelace Day! Enjoy this annual international celebration of the achievements of women in science, technology, engineering and maths (STEM). findingada.com

“The most important thing about #AI isn't its technical capabilities or limitations. The most important thing is the investor story and the ensuing mania that has teed up an economical catastrophe that will harm hundreds of millions or even billions of people.” pluralistic.net/2025/09/27/e...

A microsimulation model to estimate the impact of care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database. www.jclinepi.com/article/S089... Via @jclinepi.bsky.social

ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. https://bit.ly/47Wxc59

🚨Emerging Point-of-Care Testing in Genomics Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social

The contribution of conference abstracts in #systematicreviews - "Their inclusion changed the effect estimate in 55.6% and imprecision in 16% of cases when using MIDs. In a few instances, CAs also influenced RoB and inconsistency assessments." www.jclinepi.com/article/S089... @jclinepi.bsky.social

Most Americans still don’t know that #alcohol can cause #cancer — and the alcohol industry and Trump are working hard to make sure it stays that way by discrediting and burying a new report that offers new evidence of the link between drinking alcohol and dying www.vox.com/health/46008... @vox.com

In a new #ScienceExpertVoices article, Seth Berkley unravels the arc of vaccine progress. https://scim.ag/3VrCDBx

Most air cleaning devices have not been tested on people, and little is known about their potential harms. Professors of medicine and public health explain:

New #research that could help clinical trials avoid early termination. Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation. www.jclinepi.com/article/S089... Via @jclinepi.bsky.social

A really thought-provoking article from @elife.bsky.social about manuscript publication, peer review and who acts as the gatekeepers of publishing: “why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down?” sfdora.org/2025/07/30/s... H/T @hildabast.bsky.social

A Review in Nature Reviews Endocrinology assesses the role of ultra-processed foods in obesity, examining the epidemiological evidence, biological mechanisms and implications for policymakers. go.nature.com/44zGHoO 🍎📃 #medsky 🧪

In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes.

#SupportOLSPub - every vote counts The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here. blog.zbmed.de/olspub-support

The MAHA report critique, by @hiltzikm.bsky.social www.latimes.com/business/sto... And the Trojan horse, by @drjengunter.bsky.social vajenda.substack.com/p/hijacking-...

The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial @nejm.org nejm.org/doi/full/10....

In the wake of several countries legalising #marijuana, questions remain about the drug's long-term #health effects. A new study has found that people who smoke weed or use edibles do worse on measures of vascular health that predict cardiovascular risk. jamanetwork.com/journals/jam... @jama.com

A scoping review of carbon emissions associated with clinical trials finds that several trial activities, including travel and meetings, trial facilities, and sample & lab activities, are consistently carbon heavy. www.jclinepi.com/article/S089... @jclinepi.bsky.social #scopingreview #openaccess

Brand new SPIRIT and CONSORT #reporting #guidelines are out now! 🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist 🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist www.jclinepi.com/article/S089... @jclinepi.bsky.social #SPIRIT #CONSORT #RCTs #protocols

What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A new reporting guideline has just been published for the involvement of patients and caregivers in identifying and designing healthcare interventions: the IDEAS framework www.jclinepi.com/article/S089... HT @jclinepi.bsky.social #OA #openaccess #IDEAS #coproduction #patients #partners #research

The RTS,S/AS01E malaria vaccine has been successfully administered to over 2 million children since 2019. On #WorldMalariaDay, a paper in @lancetgh.bsky.social reports the results of a study evaluating RTS,S/AS01E safety and effectiveness in real-world settings: tinyurl.com/3jthn39h

Electronic patient records (EPRs) can potentially transform health care delivery, improving quality, efficiency and patient safety. Most trusts in England now have EPRs but many are not yet using them to their full potential. We explored the challenges in our recent analysis ⬇️

Out of the top 25 most-cited papers in the 21st century, the #PRISMA statement comes in at number 6 with a mind-boggling 133,965 citations according to Web of Science. www.nature.com/articles/d41... H/T @nature.com #systematicreviews #evidence #evidencesynthesis #statistics #data #citations

Large language models for conducting systematic reviews: on the rise, but not yet ready for use—a scoping review. "Although LLMs show promise in supporting SR creation, fully established or validated applications are often lacking" www.jclinepi.com/article/S089... via @jclinepi.bsky.social #AI #LLM

A new study from @jclinepi.bsky.social explores methods for retrieving publications not indexed in PubMed and Embase, examining coverage of various specialties to determine the most effective search strategies for systematic reviews. www.jclinepi.com/article/S089... #OA #searches #evidence #SLR