The TARGET reporting guidelines for target trial emulation studies have arrived! #EpiSky #CausalSky jamanetwork.com/journals/jam...

Adjuvant chemotherapy and hormonotherapy versus adjuvant hormonotherapy alone for women aged 70 years and older with high-risk breast cancer based on the genomic grade index (ASTER 70s): a randomised phase 3 trial - The Lancet www.thelancet.com/journals/lan...

In this blog, Jack Elliott and Elaine Kelly examine trends in unpaid overtime among NHS staff since 2019 and consider the implications for future productivity. Read more ⬇️ https://bit.ly/4mILY3C

Preprint "The C-Index Multiverse" arxiv.org/abs/2508.14821

Target trial emulation is an important, useful idea, but we must remain careful to not allow novices to think it's a magical shortcut to causal inference. Nor can we lose sight of the *main* thing that separates randomized from non-randomized studies.

Do. Not. Give. This. To. The. Medics. PLEASE.

Vaginal estrogen therapy initiation after breast cancer and oncological outcomes: a nationwide population-based target trial emulation. https://www.medrxiv.org/content/10.1101/2024.10.23.24315966v1

We're hiring! A vacancy has opened up in the team for the position of Post-Doctoral Research Fellow. 🔬 🧑🏼‍💻 If this sounds like something you'd be interested in, details can be found on our website below. 👇 cancer-data.ecrc.ed.ac.uk/2025/03/07/r...

Haven't registered your place for the Beatson International Cancer Conference 2025 yet? Find out what delegates had to say about last year's event 📅Register by 21 March: beatsonconference.org #BICC2025

Today is the 4th Edinburgh Breast Cancer Special Symposium #EBCSS25 www.ebcss.org

A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer www.nature.com/articles/s41...

📌 Adjuvant Atezolizumab for Early Triple-Negative Breast CancerThe ALEXANDRA/IMpassion030 Randomized Clinical Trial jamanetwork.com/journals/jama/… @oncoalert.bsky.social

Annual versus less frequent mammographic surveillance in people with breast cancer aged 50 years and older in the UK (Mammo-50): a multicentre, randomised, phase 3, non-inferiority trial - The Lancet www.thelancet.com/journals/lan...

Together with the NIHR (National Institute for Health and Care Research), the EPSRC, Health Data Research UK (HDR UK) and ADR UK (Administrative Data Research UK), we’re announcing a £10m programme which will help identify individual cancer risk 🙌 Read more 👉 cruk.ink/42q0aaY

So happy to share the latest study from NOTCH led by Dr Karen Mactier from @NHS_Lothian @UofGlasgow, looking at UK-wide practice in managing a rare cancer, uterine sarcoma 👇👇👇 pubmed.ncbi.nlm.nih.gov/39725428/

Are you a health economist, epidemiologist or data scientist with experience using routine healthcare data? Interested in equity in cancer care? Come and join this exciting @nihr.bsky.social funded project! Work with a range of stakeholders and build your skills. jobs.leeds.ac.uk/Vacancy.aspx...

4w Denosumab or 12w The efficacy results of the REDUSE study are not mature yet but the tox results are in Less drug - fewer tox events ONJ all grades 8.1 vs 5.2% #SABCS24

#SABCS24 FDA session highlighting need to consider Minimum Effictive Dose, not just Maximum Tolerated Dose. Reminds me of the GO2 trial in gastric ca last decade. Breast cancer drug development catching up? jamanetwork.com/journals/jam...

The Sudlow Review on the challenges and opportunities for using UK linked healthcare data for research www.hdruk.ac.uk/helping-with...

Our latest in @naturecomms.bsky.social from @danafarber.bsky.social / @mskcc.bsky.social collaboration: AI to extract cancer outcomes in EMR! www.nature.com/articles/s41...

Very good to see more de-escalation trials publishing in HER2 positive early breast cancer. Here the HELEN-006 trial. www.thelancet.com/journals/lan...

📣 Check out this recent study: UK national observational cohort study investigating Tolerance of Anti-cancer Systemic Therapy in the Elderly: the TOASTIE study From @drmarkbaxter.bsky.social and colleagues: bmjoncology.bmj.com/content/3/1/... #cancer #chemotherapy

This is how we should be doing Oncology trials - the Dutch SONIA trial looking at treatment sequencing of CDK 4/6 inhibitors in advanced breast cancer. A self funding efficiency trial! #oncsky www.nature.com/articles/s41...

Our latest mixed-methods paper in #bmjopen describes where cancer patients and staff found benefit in using an eHealth #proms based intervention as part of routine care during systemic/chemo treatment. bmjopen.bmj.com/content/bmjo...

Any good starter packs out there for folks using routine healthcare data for cancer research? #oncsky #cancerinformatics #causalinference

Illness trajectories of incurable solid cancers We need to shift our approach to ambulatory palliative care education to managing patients over years and also define the boundaries and ways to collaborate between us and primary care for those living with cancer pubmed.ncbi.nlm.nih.gov/38428972/

🧵 New research published today by the OECD: 💷 #Cancer adds £14.4bn to annual UK #health expenditure - even accounting for other health costs those who don't get cancer go on to require 📈Without action, per capita costs could increase by >50% by 2050 1/ news.cancerresearchuk.org/2024/11/21/t...

Patients with #cancer favour evidence of success over quick drug approvals. Ajay Aggarwal explains while offering patients new treatment options is crucial, survey suggests not all patients want faster cancer drug approvals without certainty they work. #PublicHealth www.lshtm.ac.uk/newsevents/n...

So here’s a starter pack of the UK Oncologists I’ve found so far - LMK who I have missed and I will follow and add.

open.substack.com/pub/rorycell... My latest healthtech Substack post is about those annoying letters that are addressed to your GP but should be written for the patient

I've created a #healtheconomics starter pack! There's a few other great packs out there but in this one I've tried to make it more international! 🌎 Let me know if you'd like to be added or if you have recommendations. And feel free to share! go.bsky.app/8Lj8FLB

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

Looking for collaborators to work on federated Real World Evidence studies related to cancer. We are building our infrastructure and need high value demonstaror projects. #OHDSI #EHDEN #OMOP #RWE please get in touch

Hello Bluesky. I am an academic oncologist trying to improve use of routinely collected healthcare data for evidence based decision making. Background in Health Economics. Trying to keep up with data science. I treat patients with breast cancer at Edinburgh Cancer Centre. #oncology #rwe #healthecon

Automated real-world data integration improves cancer outcome prediction

How should we audit 'best supportive care' in poor prognosis cancers? What metric is measurable and objective? Any ideas?