New online! Bismuth-photocatalysed Heck-type coupling with alkyl and aryl electrophiles

Ambiphilic cross-coupling.

🔥 An approach for light-driven, Ni-catalyzed C-heteroatom couplings that: -Couples tough nucleophiles (yes, 3° alcohols!) -Couples electron-rich aryl bromides -Doesn't need a PC -Runs on 100 ppm Ni -Delivers on drug syntheses and late-stage modifications Now on @chemrxiv.org: tinyurl.com/3ss6x24j

Josep Cornella & co-workers @cornellab.bsky.social unveil one-step heteroatom exchange🚀 A Ni(0)-catalyzed route converts #isoxazoles & #oxadiazoles into #pyrazoles & 1,2,4-triazoles🧪 A blueprint for rapid #azole scaffold exploration without de novo synthesis🌟 #nickel 👉 buff.ly/BabxqGG

🚨Calling medicinal chemists🚨: A Suzuki het-het coupling sometimes does not require complex ligands. An air stable Ni would do. Amazing work from Rakan Saeb and Byeongdo Roh. onlinelibrary.wiley.com/doi/10.1002/...

Deciphering the mechanism of oxidative addition of aryl iodides into a red-light active bismuthinidene. Incredible team: Alexios Stamoulis, Mauro Mato, Paolo Cleto-Bruzzese, M. Leutzsch, M. Gil-Sepulcre, A. Cadranel and F. Neese. pubs.acs.org/doi/10.1021/...

Transmetalating a challenging tetrel: introducing aryl-[Si] synthons into bismuth organometallic catalysis. Great work spearheaded by Teresa and Sophia. onlinelibrary.wiley.com/doi/10.1002/...

The OMCOS-22 website has been updated. Registration and abstract submission are now open. Dr. Josep Cornella has been selected as the recipient of the OMCOS 22 Award. We congratulate Dr. Cornella and look forward to his award lecture in Kyoto. #OMCOS-22 omcos22.org

Congratulations to Scripps Research Prof. Benjamin Cravatt, PhD, on receiving the 2025 William H. Nichols Medal from @amerchemsociety.bsky.social for his pioneering work in activity-based protein profiling, advancing drug discovery for cancer & neurological disorders.

👋🏽 posting soon!