SHUBHAM
@shubham-das.bsky.social
📤 19
📥 72
📝 5
Postdoctoral Fellow at
@stanford.edu
New preprint: We identify a dual regulatory role of nuclear FNBP4 in actin dynamics: the C-terminus binds actin, while the N-terminus inhibits the formin FMN1. Thanks to @Sankar_Maiti @iiserkol,
#Actin_Cytoskeleton_Dynamics_Lab
doi.org/10.64898/202...
#actin
#biochemistry
#nucleus
#formin
#fnbp4
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https://doi.org/10.64898/202..
2 months ago
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reposted by
SHUBHAM
John Wallingford
3 months ago
Meeting Alert! Santa Cruz Developmental Biology Meeting! 👇
@socdevbio.bsky.social
@insdb.bsky.social
@bscb-official.bsky.social
@isdb.bsky.social
@bsdb.bsky.social
@ascbiology.bsky.social
add a skeleton here at some point
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reposted by
SHUBHAM
Rockefeller University Press
5 months ago
Perspective
@jcb.org
by Richard McIntosh describing the history of research on
#microtubule
polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers.
rupress.org/jcb/article/...
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reposted by
SHUBHAM
Journal of Cell Science
7 months ago
Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by
@abbybuch.bsky.social
alongside JCS Editor Megan King
@luskinglab.bsky.social
. Deadline: 3 November
journals.biologists.com/jcs/pages/nu...
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🚨 New publication out in @jbiolchem! We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding! 🔗
doi.org/10.1016/j.jbc.…
#ActinCytoskeleton
on
www.jbc.org/article/S002...
xt
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Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics
Formin1 (FMN1), a member of the non-diaphanous formin family, is essential for development and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject to canonical autoinhibition thr...
https://www.jbc.org/article/S0021-9258(25)00399-0/fulltext
8 months ago
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reposted by
SHUBHAM
over 1 year ago
Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics
www.biorxiv.org/content/10.1...
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Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics
Formin1 (FMN1), a member of the non-diaphanous formin family, is essential for development and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject to canonical autoinhibition thr...
https://www.biorxiv.org/content/10.1101/2024.12.07.627365v1
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Actin fell in love with nucleus ❤️
#actin
#cytoskeleton
#nucleus
#microscopy
#cellbiology
#research
8 months ago
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