For #3DThursday: a ~5 mm Parhyale hawaiensis female (with hatchlings!) imaged by #nanoCT. 🔍🦐 This tiny amphipod is a powerful #devbio model organism. 🥼 Neeharika Verma, Nipam Patel Lab 🔬 @zeiss-microscopy.bsky.social Versa 620 XRM 🏛️ @mblscience.bsky.social, UF Nanoscale Research Facility 🎬 #syGlass

🦎 A gorgeous Axolotl dataset for #3DThursday before I head to MBL for #NESDB2026. Those are tiny shrimps 🦐 in its stomach! 🔬: ZEISS Xradia 520 #microCT 🥼: Claudio Polisseni 🏛️: Max Planck Institute for Biological Intelligence @mpiforbi.bsky.social 🎬: #syGlass v2.6.0 @mblscience.bsky.social #Zeiss

We won! 🏆🥹 syGlass took Best Emerging XR Startup + Best Applied XR Product at #HarvardXR this weekend. Best part (besides surviving the pitch 💀) was live demos on the #Sony Spatial Reality Display, including this #microCT of a chameleon embryo from R Diaz More soon 👀 #XR #3DVisualization #syGlass

#UMAP in VR for #3DThursday! In this zebrafish embryogenesis dataset, RNA-seq + ATAC-seq across 94k+ cells reveal changing regulatory programs over time. 🥼 Yang-Joon Kim, Loic Royer @loicaroyer.bsky.social , Matthias Haury 📝 www.biorxiv.org/content/10.1... 🏛️ Biohub @biohub.org 🎬 #syGlass v2.6.0

Stereoscopic visualization + 3D control. It's a powerful combination for exploring & analyzing 3D image data, & a VR headset is no longer required to achieve it. Combining modern, glasses-free 3D displays with 6 DoF controllers is a very low-friction way to reap the benefits of immersive workflows.

Excited to see direct streaming of @openmicroscopy.org @zarr.dev datasets in #syGlass! Exploring huge images without upfront download is just what we’ve been working toward with cloud-optimized formats. Great to have tools connecting the ecosystem of imaging repositories, now including VR 🙌

syGlass reads image data from many file formats: some open, some proprietary. Few are as exciting and dynamic as OME-Zarr, and direct streaming of these files is only the beginning of what's possible. More on our support for OME-Zarr in syGlass v2.6.0 below.

Segmenting image volumes has long been a feature of syGlass, but our latest release adds the ability to segment surfaces as well. A nice ~45 second demo of this below!

The first syGlass feature release of the year is here! Meet syGlass v2.6.0: 🖥️ Spatial Reality Display support 🛜 Stream/read OME-Zarr directly 🖌️ Partition surfaces via 3D brush ⌨️ Enter text via in-VR keyboards www.syglass.io/blog/syglass...

For rapid creation of immersive narrative content from 3D image data, there is no more capable tool than syGlass. Narrations like these can be viewed in fully immersive VR; as 2D, stereo-3D, or 360 video; or as an anaglyph scene for viewing with red/cyan 3D glasses. Create once & deploy anywhere!

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

Label-free #holotomography for #3DThursday! This imaging technique lets you follow the same living organoid in 4D with no dyes or phototoxicity. 🔬: @tomocube.bsky.social, HT-X1 🧫: Mouse Intestinal #Organoid 🏛️: Institut Pasteur Workshop, Pushing the Frontiers of Dynamic Imaging 🎬: #syGlass, v2.5.0

#syGlass v2.5.0 is out! 🎉 New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share. Blog: www.syglass.io/blog/syglass... #Microscopy #Imaging #3DThursday

Stereoscopic visualization can be achieved in a variety of ways, each with their own advantages. One of the many strengths of syGlass is its ability to seamlessly switch between them: immersive virtual reality, anaglyph (red/cyan) rendering, and now Sony's glasses-free 3D displays.

For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context. 🔬 #MicroCT of a P1 mouse 🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social 🎬 syGlass.io #Microscopy #SciComm #3DVisualization #syGlass

💧 A male water flea (#Daphnia magna) for #3DThursday! Yellow 🟨 is musculature, magenta/gray 🟪 shows autofluorescence of its outer cuticle. 🔬: Fluorescence Microscopy 🥼: Carsten Wolff 🏛️: Marine Bio Lab @mblscience.bsky.social 🎬: syGlass.io #EnvironmentalScience #MBL #SciComm #Microscopy #syGlass

🍺 It’s Oktoberfest, so let's look inside beer foam! Non-destructive imaging like this is key for food science and helps us understand how structure and stability affect things like aroma and taste. 🔬: TESCAN DynaTOM #microCT 🥼: Wesley De Boever 🎬: syGlass.io #Oktoberfest #3DThursday #Microscopy

👀 #3DThursday: Cross your eyes to see this super res pollen dataset in 3D! Good old fashioned stereo pairs in #syGlass bringing science to life. 🌿✨ 🔬: Zeiss LSM 980 with Airyscan 2 🥼: Nat Prunet, @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core: tarheels.live/biologymicro... 🎬: syGlass.io

Non-destructive testing for #3DThursday!🥽 Apple Vision Pro vs MetaQuest in a microCT. 🔬: Lumafield @lumafield.bsky.social microCT 🎬: syGlass.io, loading two projects at once 3D imaging like this is used to validate design, catch flaws, and build smarter devices. #MicroCT #syGlass #VR #SciComm

Pollen diversity #3DThursday!🌼🌾 Thanks to Nat Prunet's careful microscopy, we see ridges, spikes & pores that reveal how plants spread & survive. 🔬: @zeiss-microscopy.bsky.social LSM 980, Airyscan 2 🥼: @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core 🎬: syGlass.io v2.4.0 #syGlass

Chicken balancing for #3DThursday!🐔 These utricle hair cells sense gravity & straight-line motion. We segmented them with #CellposeSAM in #syGlass. 🥼: Stefan Heller Group 🏛️: Stanford @stanfordmedicine.bsky.social 🎬: syGlass.io v2.4.0, out now! #Neuroanatomy #Microscopy #3DVisualization #SciComm

It's #MicroscopyMonday! Today we have a very special confocal dataset that HIGH SCHOOL students were able to label and image themselves at the MBL. 🐟: #Zebrafish 🔬: Nipam Patel, High School Science Discovery Programs 🏛️: @mblscience.bsky.social 🎬: syGlass.io #NESM #Confocal #SciComm #ScienceEd

4D bread baking inside a microCT for #3DThursday?!🍞 🔬: TESCAN DynaTOM 🏛️: TESCAN, thanks to Marijn Boone for the data! 🎬: syGlass.io Total scan time: 22m8s Time for 1 scan: 10 seconds Total scans: 124 volumes #4DImaging #MicroCT #DynamicImaging #FoodScience #syGlass #VRVisualization #ScientificVR

Automated Segmentation by Cellpose-SAM using syGlass for #3DThursday! This took about 30 minutes to run on one of the gaming laptops. Crazy. 🔬: Synchrotron #MicroCT 🥼: Keith Cheng, MD, PhD, @pennstateuniv.bsky.social 📝: #CellposeSAM www.biorxiv.org/content/10.1... 🥽: syGlass.io v2.4.0 -- out soon!

I love this for #3DThursday -- Zebrafish, but make it four and layer them! 🥼: Arnim Jenett 🏛️: TEFOR tefor.net/en/ 🔬: #Lightsheet 🎬: syGlass in colorblind mode, #syGlass Check it out for yourself with their resource "The Larval Standard Brain": zebrafish.tefor.net#/home?_k=fz1...

A #microscopy mystery for #3DThursday!🌾 What is this? 🔍 Things that I know: it is a #plant, it was imaged on a Lumafield #microCT, and the color is a LUT (look up table) that I applied in #syGlass and has nothing to do with the organism (microCT comes in as grayscale). Help! #SciComm

Happy 4th for #3DThursday! 🎉 Do I occasionally forget and then remember ecstatically that we have a confetti cannon in the syGlass room? Yes, yes, I do ... #syGlass #VRScience #Microscopy #SciComm

Finally plants for #3DThursday!🌽 A maize root tip, imaged using #microCT, from the Topp Roots Lab. 🔬: @zeiss-microscopy.bsky.social Versa 520 XRM 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 📝: academic.oup.com/plphys/artic... 🎬: syGlass.io #syGlass

Get your 3D glasses out for #3DThursday! And click the link below to see syGlass on the really big screen at the @mit.edu MIT Museum last week. (guys it's my first syGlass blog ...) 📝: www.syglass.io/blog/a-night... 🥼: Kory Evans @sternarchella.bsky.social , Rice University 🎥: syGlass.io #syGlass

LIVE sea urchin larvae for #3DThursday! Catch me at the MIT Museum tonight at AfterDark and see it in person. 🔬: @brukercorporation.bsky.social TruLive3D 🥼: Amro Hamdoun @hamdounlab.bsky.social ‬, Tzer Han Tan's @tzerhan29.bsky.social group at UCSD 🌌: Painted Sea Urchin 🎥: syGlass.io #syGlass

Up in Acadia at the @mdibiolab.bsky.social for #LSFM25! Here's a cleared whole mouse head on the SmartSPIM, 3.6X objective for #3DThursday. 🔎 @jtakatoh.bsky.social, now at @stonybrooku.bsky.social 🔬 LifeCanvas Technologies, lifecanvastech.com/products/sma... 🥽 syGlass.io @lsfm-na.bsky.social

✨ Heading to @mdibiolab.bsky.social next week for the LSFM course! Here’s some stunning lightsheet data from @erturklab.bsky.social 🔬: Blaze Ultramicroscope, LaVision Biotech 🥼: Hongcheng Mai, Jie Luo, Helmholtz Munich 📝: pmc.ncbi.nlm.nih.gov/articles/PMC... 🎬: syGlass.io #3DThursday #LSFM2025

For #3DThursday, whole mouse liver imaged with #mesoSPIM light sheet microscopy! Showing how structure meets function across the organ. 🥽: syGlass.io 🥼: Hei Ming Lai 📝: INSIHGT -> www.nature.com/articles/s41... 🏛️: Chinese University of Hong Kong #LightSheet #SciComm #3DImaging #syGlass

In the age of AI annotation tools, why use VR to segment or track objects in your image volumes? My answer + more on new features from our spring release of syGlass: www.syglass.io/blog/syglass...

Every quarter, our fantastic development team at syGlass breaks new ground at the intersection of scientific research and virtual reality. This spring release is the best iteration of syGlass yet, with many improvements under the hood in addition to the new features below.

For #3DThursday, a cleared axolotl on a line confocal! 🥽: syGlass.io 🔬: Dual-View Line Scanning Confocal: www.mbl.edu/research/res... 🥼: @ryliewalsh.bsky.social, @mblscience.bsky.social 🐉: @murawalalab.bsky.social, @mdibiolab.bsky.social 🏛️: MBL Center for Innovation in Imaging and Image Analysis

Comparison may be the thief of joy, but in devbio it’s how researchers understand how life takes shape. Excited to be at SDB Northeast this weekend! www.sdbonline.org/nesdb2025 🔬: Zebrafish, synchrotron micro-CT 🥼: chenglab.io 🥽: syGlass.io #DevBio #Zebrafish #syGlass #3DImaging #3DThursday

Expansion Microscopy (ExM) for #3DThursday! Nanoscale details, regular microscope.🤯 🥼 Ksena Longrin 🥽 syGlass.io 🟦 vGlut1, Vesicular glutamate transporter 1 🟨​ Kv3.3 , a voltage-gated potassium ion channel subunit 🔬 @ZEISS Microscopy LSM980 📝 doi.org/10.7554/eLife.75219

It's been a tough year or so for em dashes. They're largely now considered hallmarks of AI-generated writing: both overused by LLMs and inconvenient for humans to type. I still like to use them where appropriate, and I've taken to using an AutoHotkey shortcut to do so.

🧠It's a #3DThursday Sholl analysis in syGlass.io! This is a method to quantify neuronal branching by counting dendritic intersections with concentric circles around the soma. Simple but powerful! 🔬📊 #Neuroscience #Microscopy #syGlass #Neurobiology #SciComm

Throwback from 2023: People are always asking me, "how hard is it to learn to use syGlass?" This student is a great example -- 10 seconds in the headset and he's ready to explore. That's because interacting with 3D objects is the same in real life and in VR: reach out and grab it!

Happy #3DThursday! Today we'll explore a SUB(!!)-volume of 500GB from a cleared, intact mouse brain from Jose Maldonado at Vanderbilt. You can see how we render these enormous data on consumer grade GPUs. 🥽💻 🔎 @josemald.bsky.social, @vucellimaging.bsky.social 🔬 lifecanvastech.com 🥽 syglass.io

It's #3DThursday, and today I’m in VR, looking at scan of a VR, while wearing the same VR ... it’s VR inception, and I am here for it. This is a #microCT from the folks over at @lumafield.bsky.social of a Meta Quest VR in syglass.io!

🐋Using CT scan data & syGlass.io, Joy Reidenberg is stepping inside a baby sperm whale’s anatomy—unlocking new discoveries through immersive 3D visualization. A game-changer for comparative anatomy & science education! 🌊🥽 #3DThursday #VR #MarineBiology #CT 📝: www.syglass.io/blog/blubber...

Anaglyph 3D might not be the most cutting-edge tech for stereoscopic viewing, but it does have a place in providing a low-cost, easy to distribute 3D experience.

With syGlass #VR, students aren’t just learning about science: they’re stepping inside it. And in doing so, they’re shaping the future of education itself. #EduSky #VirtualReality #SciComm #HealthScience #Neuroscience #STEM www.syglass.io/blog/bergen-...

🩻CT scans can be hard to interpret for experts — imagine how patients feel! 3D visualization tools like syGlass.io allow doctors can rotate, zoom, and highlight key structures, making it easier to explain findings and treatment options. #3DThursday #CTScan #PatientCommunication #syGlass