For rapid creation of immersive narrative content from 3D image data, there is no more capable tool than syGlass. Narrations like these can be viewed in fully immersive VR; as 2D, stereo-3D, or 360 video; or as an anaglyph scene for viewing with red/cyan 3D glasses. Create once & deploy anywhere!

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

Label-free #holotomography for #3DThursday! This imaging technique lets you follow the same living organoid in 4D with no dyes or phototoxicity. 🔬: @tomocube.bsky.social, HT-X1 🧫: Mouse Intestinal #Organoid 🏛️: Institut Pasteur Workshop, Pushing the Frontiers of Dynamic Imaging 🎬: #syGlass, v2.5.0

#syGlass v2.5.0 is out! 🎉 New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share. Blog: www.syglass.io/blog/syglass... #Microscopy #Imaging #3DThursday

Stereoscopic visualization can be achieved in a variety of ways, each with their own advantages. One of the many strengths of syGlass is its ability to seamlessly switch between them: immersive virtual reality, anaglyph (red/cyan) rendering, and now Sony's glasses-free 3D displays.

For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context. 🔬 #MicroCT of a P1 mouse 🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social 🎬 syGlass.io #Microscopy #SciComm #3DVisualization #syGlass

💧 A male water flea (#Daphnia magna) for #3DThursday! Yellow 🟨 is musculature, magenta/gray 🟪 shows autofluorescence of its outer cuticle. 🔬: Fluorescence Microscopy 🥼: Carsten Wolff 🏛️: Marine Bio Lab @mblscience.bsky.social 🎬: syGlass.io #EnvironmentalScience #MBL #SciComm #Microscopy #syGlass

🍺 It’s Oktoberfest, so let's look inside beer foam! Non-destructive imaging like this is key for food science and helps us understand how structure and stability affect things like aroma and taste. 🔬: TESCAN DynaTOM #microCT 🥼: Wesley De Boever 🎬: syGlass.io #Oktoberfest #3DThursday #Microscopy

👀 #3DThursday: Cross your eyes to see this super res pollen dataset in 3D! Good old fashioned stereo pairs in #syGlass bringing science to life. 🌿✨ 🔬: Zeiss LSM 980 with Airyscan 2 🥼: Nat Prunet, @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core: tarheels.live/biologymicro... 🎬: syGlass.io

Non-destructive testing for #3DThursday!🥽 Apple Vision Pro vs MetaQuest in a microCT. 🔬: Lumafield @lumafield.bsky.social microCT 🎬: syGlass.io, loading two projects at once 3D imaging like this is used to validate design, catch flaws, and build smarter devices. #MicroCT #syGlass #VR #SciComm

Pollen diversity #3DThursday!🌼🌾 Thanks to Nat Prunet's careful microscopy, we see ridges, spikes & pores that reveal how plants spread & survive. 🔬: @zeiss-microscopy.bsky.social LSM 980, Airyscan 2 🥼: @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core 🎬: syGlass.io v2.4.0 #syGlass

Chicken balancing for #3DThursday!🐔 These utricle hair cells sense gravity & straight-line motion. We segmented them with #CellposeSAM in #syGlass. 🥼: Stefan Heller Group 🏛️: Stanford @stanfordmedicine.bsky.social 🎬: syGlass.io v2.4.0, out now! #Neuroanatomy #Microscopy #3DVisualization #SciComm

It's #MicroscopyMonday! Today we have a very special confocal dataset that HIGH SCHOOL students were able to label and image themselves at the MBL. 🐟: #Zebrafish 🔬: Nipam Patel, High School Science Discovery Programs 🏛️: @mblscience.bsky.social 🎬: syGlass.io #NESM #Confocal #SciComm #ScienceEd

4D bread baking inside a microCT for #3DThursday?!🍞 🔬: TESCAN DynaTOM 🏛️: TESCAN, thanks to Marijn Boone for the data! 🎬: syGlass.io Total scan time: 22m8s Time for 1 scan: 10 seconds Total scans: 124 volumes #4DImaging #MicroCT #DynamicImaging #FoodScience #syGlass #VRVisualization #ScientificVR

Automated Segmentation by Cellpose-SAM using syGlass for #3DThursday! This took about 30 minutes to run on one of the gaming laptops. Crazy. 🔬: Synchrotron #MicroCT 🥼: Keith Cheng, MD, PhD, @pennstateuniv.bsky.social 📝: #CellposeSAM www.biorxiv.org/content/10.1... 🥽: syGlass.io v2.4.0 -- out soon!

I love this for #3DThursday -- Zebrafish, but make it four and layer them! 🥼: Arnim Jenett 🏛️: TEFOR tefor.net/en/ 🔬: #Lightsheet 🎬: syGlass in colorblind mode, #syGlass Check it out for yourself with their resource "The Larval Standard Brain": zebrafish.tefor.net#/home?_k=fz1...

A #microscopy mystery for #3DThursday!🌾 What is this? 🔍 Things that I know: it is a #plant, it was imaged on a Lumafield #microCT, and the color is a LUT (look up table) that I applied in #syGlass and has nothing to do with the organism (microCT comes in as grayscale). Help! #SciComm

Happy 4th for #3DThursday! 🎉 Do I occasionally forget and then remember ecstatically that we have a confetti cannon in the syGlass room? Yes, yes, I do ... #syGlass #VRScience #Microscopy #SciComm

Finally plants for #3DThursday!🌽 A maize root tip, imaged using #microCT, from the Topp Roots Lab. 🔬: @zeiss-microscopy.bsky.social Versa 520 XRM 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 📝: academic.oup.com/plphys/artic... 🎬: syGlass.io #syGlass

Get your 3D glasses out for #3DThursday! And click the link below to see syGlass on the really big screen at the @mit.edu MIT Museum last week. (guys it's my first syGlass blog ...) 📝: www.syglass.io/blog/a-night... 🥼: Kory Evans @sternarchella.bsky.social , Rice University 🎥: syGlass.io #syGlass

LIVE sea urchin larvae for #3DThursday! Catch me at the MIT Museum tonight at AfterDark and see it in person. 🔬: @brukercorporation.bsky.social TruLive3D 🥼: Amro Hamdoun @hamdounlab.bsky.social ‬, Tzer Han Tan's @tzerhan29.bsky.social group at UCSD 🌌: Painted Sea Urchin 🎥: syGlass.io #syGlass

Up in Acadia at the @mdibiolab.bsky.social for #LSFM25! Here's a cleared whole mouse head on the SmartSPIM, 3.6X objective for #3DThursday. 🔎 @jtakatoh.bsky.social, now at @stonybrooku.bsky.social 🔬 LifeCanvas Technologies, lifecanvastech.com/products/sma... 🥽 syGlass.io @lsfm-na.bsky.social

✨ Heading to @mdibiolab.bsky.social next week for the LSFM course! Here’s some stunning lightsheet data from @erturklab.bsky.social 🔬: Blaze Ultramicroscope, LaVision Biotech 🥼: Hongcheng Mai, Jie Luo, Helmholtz Munich 📝: pmc.ncbi.nlm.nih.gov/articles/PMC... 🎬: syGlass.io #3DThursday #LSFM2025

For #3DThursday, whole mouse liver imaged with #mesoSPIM light sheet microscopy! Showing how structure meets function across the organ. 🥽: syGlass.io 🥼: Hei Ming Lai 📝: INSIHGT -> www.nature.com/articles/s41... 🏛️: Chinese University of Hong Kong #LightSheet #SciComm #3DImaging #syGlass

In the age of AI annotation tools, why use VR to segment or track objects in your image volumes? My answer + more on new features from our spring release of syGlass: www.syglass.io/blog/syglass...

Every quarter, our fantastic development team at syGlass breaks new ground at the intersection of scientific research and virtual reality. This spring release is the best iteration of syGlass yet, with many improvements under the hood in addition to the new features below.

For #3DThursday, a cleared axolotl on a line confocal! 🥽: syGlass.io 🔬: Dual-View Line Scanning Confocal: www.mbl.edu/research/res... 🥼: @ryliewalsh.bsky.social, @mblscience.bsky.social 🐉: @murawalalab.bsky.social, @mdibiolab.bsky.social 🏛️: MBL Center for Innovation in Imaging and Image Analysis

Comparison may be the thief of joy, but in devbio it’s how researchers understand how life takes shape. Excited to be at SDB Northeast this weekend! www.sdbonline.org/nesdb2025 🔬: Zebrafish, synchrotron micro-CT 🥼: chenglab.io 🥽: syGlass.io #DevBio #Zebrafish #syGlass #3DImaging #3DThursday

Expansion Microscopy (ExM) for #3DThursday! Nanoscale details, regular microscope.🤯 🥼 Ksena Longrin 🥽 syGlass.io 🟦 vGlut1, Vesicular glutamate transporter 1 🟨​ Kv3.3 , a voltage-gated potassium ion channel subunit 🔬 @ZEISS Microscopy LSM980 📝 doi.org/10.7554/eLife.75219

It's been a tough year or so for em dashes. They're largely now considered hallmarks of AI-generated writing: both overused by LLMs and inconvenient for humans to type. I still like to use them where appropriate, and I've taken to using an AutoHotkey shortcut to do so.

🧠It's a #3DThursday Sholl analysis in syGlass.io! This is a method to quantify neuronal branching by counting dendritic intersections with concentric circles around the soma. Simple but powerful! 🔬📊 #Neuroscience #Microscopy #syGlass #Neurobiology #SciComm

Throwback from 2023: People are always asking me, "how hard is it to learn to use syGlass?" This student is a great example -- 10 seconds in the headset and he's ready to explore. That's because interacting with 3D objects is the same in real life and in VR: reach out and grab it!

Happy #3DThursday! Today we'll explore a SUB(!!)-volume of 500GB from a cleared, intact mouse brain from Jose Maldonado at Vanderbilt. You can see how we render these enormous data on consumer grade GPUs. 🥽💻 🔎 @josemald.bsky.social, @vucellimaging.bsky.social 🔬 lifecanvastech.com 🥽 syglass.io

It's #3DThursday, and today I’m in VR, looking at scan of a VR, while wearing the same VR ... it’s VR inception, and I am here for it. This is a #microCT from the folks over at @lumafield.bsky.social of a Meta Quest VR in syglass.io!

🐋Using CT scan data & syGlass.io, Joy Reidenberg is stepping inside a baby sperm whale’s anatomy—unlocking new discoveries through immersive 3D visualization. A game-changer for comparative anatomy & science education! 🌊🥽 #3DThursday #VR #MarineBiology #CT 📝: www.syglass.io/blog/blubber...

Anaglyph 3D might not be the most cutting-edge tech for stereoscopic viewing, but it does have a place in providing a low-cost, easy to distribute 3D experience.

With syGlass #VR, students aren’t just learning about science: they’re stepping inside it. And in doing so, they’re shaping the future of education itself. #EduSky #VirtualReality #SciComm #HealthScience #Neuroscience #STEM www.syglass.io/blog/bergen-...

🩻CT scans can be hard to interpret for experts — imagine how patients feel! 3D visualization tools like syGlass.io allow doctors can rotate, zoom, and highlight key structures, making it easier to explain findings and treatment options. #3DThursday #CTScan #PatientCommunication #syGlass

For #3DThursday today, we'll jump into the intricate architecture of cells in the cochlear nucleus of a mouse. Serial Block-Face Electron Microscopy, capturing nanoscale detail of synaptic connections. Imaged: Mark Ellisman, UCSD Visualized: syGlass.io Reference: elifesciences.org/articles/833...

It's #3DThursday!🔬🌈 We had a great week at the Harvard Tissue Clearing Workshop, huge thanks to: @edwardlachica3.bsky.social @the.3i.social @harvardmed.bsky.social @bostonchildrens.bsky.social Imaged: Dan Giardina & Ed Lachica, 3i Visualized: syGlass.io Sample Prep: Dharmendra Puri, HMS, BCH

syGlass v2.2.1 is available now. This minor update allows you to: 🩻 Work with BMP files from CT scans 🎭 Show and hide individual masks 🗂️ Store many mask layers per project ⏩ Auto-segment cells via CLI tool Want to give it a go? As always, free trials are available.

syGlass has partnered with Diamondback Energy to bring a virtual reality STEM Lab to students at Midland ISD's Young Women's Leadership Academy! Both Neuroscience and Anatomy & Physiology courses are offered, providing students immersive, hands-on experiences integrating technology and science data.

Happy #3DThursday! 🐍💫The Year of the Snake reminds us that transformation is possible. This microCT of a 2,000-year-old mummified Egyptian cobra reveals a story of life and renewal—preserved for centuries, waiting to be uncovered. Visualized: syGlass.io Reference: www.nature.com/articles/s41...

Happy #3DThursday! Okay, so you're looking at a zebrafish confocal image, and it's beautiful, but did you also know that you are looking at something that a high school freshman imaged? Imaged by: @mblscience.bsky.social & Nipam Patel Visualized in syGlass.io Reference: www.mbl.edu/education/hi...

What began at syGlass as an effort to revolutionize the visualization and analysis of scientific image data has also quickly become a transformational tool for hundreds of high school students. www.syglass.io/blog/bridgin...

Happy #3DThursday! Step into a kidney, captured in stunning detail using INSIHGT. This isn’t just beautiful; it’s vital, transforming how we study health, aging, and disease. I'm lost in it, I love it.🎨🔬 Imaged by Hei Ming Lai, CUHK Visualized in syGlass.io Reference: www.nature.com/articles/s41...

Congratulations to the @erturklab.bsky.social lab for another big paper on nanoparticles, with some nice manual ground-truth segmentation created in syGlass. Some pretty nice movies in supplemental materials, too! (Video speed set to 2X to accommodate Bluesky's 1 min limit)