@antoineroyant.bsky.social
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reposted by
Nicolas Caramello
16 days ago
I'm proud to present this first article from my PostDoc: We probed the different responses of metalloproteins (myoglobin, Mb and a copper-containing Nitrite Reductase, CuNIR) to reduction of their metal centres by X-rays at two temperatures (100K, 392K-RT) with UV-vis absorption and diffraction.
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Coupled on-line in crystallo UVโVis absorption spectroscopy and X-ray crystallography to compare specific radiation damage in metal-containing proteins at room versus cryogenic temperature
We used on-line in crystallo UVโVis absorption spectroscopy in conjunction with X-ray crystallography on beamline BM07-FIP2 at the ESRF to compare the structural effects of specific radiation damage o...
https://journals.iucr.org/d/issues/2026/03/00/gm5121/index.html
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reposted by
Structural Biology
26 days ago
Nicolas Caramello et al.: Coupled on-line in crystallo UVโVis absorption spectroscopy and X-ray crystallography to compare specific radiation damage in metal-containing proteins at room versus cryogenic temperature...
##IUCr
https://journals.iucr.org/paper?S2059798326000690
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Coupled on-line in crystallo UVโVis absorption spectroscopy and X-ray crystallography to compare specific radiation damage in metal-containing proteins at room versus cryogenic temperature
We used on-line in crystallo UVโVis absorption spectroscopy in conjunction with X-ray crystallography on beamline BM07-FIP2 at the ESRF to compare the structural effects of specific radiation damage on two different metal-containing proteins at either room or cryogenic temperature.
https://journals.iucr.org/paper?S2059798326000690
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reposted by
Nature
27 days ago
Intense, ultrashort X-ray pulses have been used to probe the extraordinary reactions that occur in a light-sensing receptor, resolving a biochemical conundrum
go.nature.com/4tidDwm
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How a protein repurposes vitamin B12 as a light sensor
Intense, ultrashort X-ray pulses have been used to probe the extraordinary reactions that occur in a light-sensing receptor, resolving a biochemical conundrum.
https://go.nature.com/4tidDwm
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reposted by
aPaulineR
about 2 months ago
Devenez plus intelligentยทe dรจs maintenant !
mail.paulineharmange.fr/archive/ia-p...
add a skeleton here at some point
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reposted by
Ivan Gushchin
3 months ago
Cryo-EM structure of sensor histidine kinase QseE with its activator QseG. Once again AlphaFold produced great model for the complex before the experimental data were available!
doi.org/10.1128/mbio...
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reposted by
Virgile Adam
6 months ago
Our team (Pixel) and along with it our institute (IBS, Grenoble) is now officially a node of the IMAGINE consortium (for next generation imaging for biology across scales)
www.linkedin.com/posts/imagin...
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๐ฃ We are happy to welcome also our new Affiliated Entities (AEs) from Instruct ERIC nodes: CEITEC - Central European Institute of Technology-MU and CNRS IBS Pixel Team. ๐ฏ While both will workโฆ | IMA...
๐ฃ We are happy to welcome also our new Affiliated Entities (AEs) from Instruct ERIC nodes: CEITEC - Central European Institute of Technology-MU and CNRS IBS Pixel Team. ๐ฏ While both will work under ...
https://www.linkedin.com/posts/imagine-horizoneurope_we-are-happy-to-welcome-also-our-new-affiliated-activity-7344338691902873603-ExEi?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAECeI4BVJofq4LeWW5Qwp9pO8hI-prE5U4
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reposted by
CNRS Biologie
6 months ago
#ResultatScientifique๐|
Saviez-vous que certaines protรฉines de notre corps rรจglent lโhorloge biologiqueโฆ et pourraient aussi aider les oiseaux ร trouver leur chemin en plein vol ? ๐ฆ โ๏ธ
@antoineroyant.bsky.social
๐ Science Advances |
buff.ly/xSpVhGC
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Dans la structure des cryptochromes, le secret des horloges et boussoles biologiques
Les cryptochromes, protรฉines sensibles ร la lumiรจre bleue, rรจglent notre horloge biologique et pourraient aussi servir de boussole interne aux oiseaux m
https://buff.ly/xSpVhGC
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reposted by
ๅฑฑๅ ๆทณๅนณ/Junpei Yamamoto
6 months ago
Our collaborative work has been published in Communications Chemistry. Congrats to the co-authors!
www.nature.com/articles/s42...
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Infrared and ultraviolet spectroscopic characterization of a key intermediate during DNA repair by (6-4) photolyase - Communications Chemistry
(6-4) photolyases repair carcinogenic pyrimidine(6-4)pyrimidone photoproducts, a process that requires two successive photons but whose mechanistic details remain elusive. Here, the authors use time-r...
https://www.nature.com/articles/s42004-025-01625-9#citeas
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reposted by
IUCrJ
6 months ago
Mโichihiro Suga: Illuminating DNA repair in action: structural insights into a photocaged glycosylase complex
##XRayFreeElectronLasers
##XFELs
##TimeResolvedCrystallography
@okayama_uni...
##IUCr
https://journals.iucr.org/paper?S2052252525007353
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Illuminating DNA repair in action: structural insights into a photocaged glycosylase complex
Structural analysis of the co-crystal between human DNA glycosylase hOGG1 and a light-sensitive substrate analog highlights its utility as a platform for real-time observation of catalytic dynamics.
https://journals.iucr.org/paper?S2052252525007353
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reposted by
Mike Hough
6 months ago
New paper describing use of photocaged nitric oxide for time resolved crystallography within fixed targets at XFEL and synchrotron - PhD work of Pete Smyth & Lewis Williams - great collaboration with
@jarworrall.bsky.social
, beamline I24 and SACLA. Funded by BBSRC
journals.iucr.org/m/issues/202...
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Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system...
https://journals.iucr.org/m/issues/2025/05/00/car5004/index.html
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reposted by
IUCrJ
8 months ago
Tomoki Imura et al.: Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
##DNARepair
##PhotocagedSubstrateAnaloga
##HOgg1
@osaka_univ_e...
##IUCr
https://journals.iucr.org/paper?S2052252525006062
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Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.
https://journals.iucr.org/paper?S2052252525006062
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reposted by
BejaLab
8 months ago
CryoRhodopsins: A comprehensive characterization of a group of microbial rhodopsins from cold environments
www.science.org/doi/10.1126/...
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CryoRhodopsins: A comprehensive characterization of a group of microbial rhodopsins from cold environments
Spectroscopy, structural, and functional study of microbial rhodopsins with characteristic long-living nearโUV-absorbing state.
https://www.science.org/doi/10.1126/sciadv.adv1015?ai=v7cg
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reposted by
EMBL
8 months ago
EMBL Hamburg scientists have discovered a group of microbial cold-loving molecules, โcryorhodopsinsโ, with extraordinary abilities. They are the first observed molecules that can act as both on and off switches for electrical activity in cells.
www.embl.org/news/science...
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reposted by
sarahejbowman
8 months ago
Excited that our article made the cover of the July issue of
@actacrystf.iucr.org
! Congrats to my coauthors
@gabbygrowsxtals.bsky.social
& Vivian Stojanoff! Grateful for
#NIH
NIGMS R24 National Resource grant that enables workshops like the 2023 SAMPREP workshop @
@acastructuralsci.bsky.social
add a skeleton here at some point
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reposted by
ESRF
10 months ago
Scientists unveil the mechanism of light-sensing proteins that regulate internal clock. They used the TR-icOS instrument at the ESRF for spectroscopic characterization of the crystals.
www.esrf.fr/home/news/ge...
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reposted by
Institut Laue-Langevin - Neutrons For society
11 months ago
๐๐ฎ๐ซ๐ซ๐๐ง๐ญ ๐๐ง๐ ๐๐ฎ๐ญ๐ฎ๐ซ๐ ๐ฉ๐๐ซ๐ฌ๐ฉ๐๐๐ญ๐ข๐ฏ๐๐ฌ ๐๐จ๐ซ ๐ฌ๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐๐ญ ๐ญ๐ก๐ ๐๐ซ๐๐ง๐จ๐๐ฅ๐ ๐๐๐ ๐๐๐ฆ๐ฉ๐ฎ๐ฌ: ๐ ๐๐จ๐ฆ๐ฉ๐ซ๐๐ก๐๐ง๐ฌ๐ข๐ฏ๐ ๐จ๐ฏ๐๐ซ๐ฏ๐ข๐๐ฐ - in ๐๐ฐ๐ถ๐ณ๐ฏ๐ข๐ญ ๐ฐ๐ง ๐๐บ๐ฏ๐ค๐ฉ๐ณ๐ฐ๐ต๐ณ๐ฐ๐ฏ ๐๐ข๐ฅ๐ช๐ข๐ต๐ช๐ฐ๐ฏ. The European Photon and Neutron campus host the ILL,
@embl.org
,
@esrf.fr
โ and the French Institut de Biologie Structurale.
www.ill.eu/news-and-eve...
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reposted by
Nicolas Caramello
10 months ago
At long last, our first article on the TR-SFX study of light signalling in a cryptochrome (the animal-like cryptochrome from C. rheinardtii) is finally out! It features some of the most beautiful maps I have ever worked with and insight on the role of FAD protonation in committing CraCRY... (1/3)
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Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.
https://www.science.org/doi/10.1126/sciadv.adu7247
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reposted by
ๅฑฑๅ ๆทณๅนณ/Junpei Yamamoto
10 months ago
Congrats for publication!๐ฅณ๐Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography | Science Advances
www.science.org/doi/10.1126/...
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Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.
https://www.science.org/doi/10.1126/sciadv.adu7247
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reposted by
Virgile Adam
11 months ago
Sometimes I forget why I always loved so much studying FPs, and sometimes I remember!
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reposted by
Acta Cryst A
about 1 year ago
Lidin et al.: Sine Ydun Larsen (1943โ2025) @lundsuni...
##IUCr
https://journals.iucr.org/paper?S2053273325001019
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Sine Ydun Larsen (1943โ2025)
Sine Larsen, former President and former General Secretary and Treasurer of the IUCr, is remembered.
https://journals.iucr.org/paper?S2053273325001019
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reposted by
LINXS
about 1 year ago
Registrations are open for the 7th International Symposium on Diffraction Structural Biology, hosted by the Partnership for Structural Biology (PSB) between EMBL, ESRF, ILL, and Institut de Biologie Structurale (IBS). Details:
www.linxs.se/events/2025/...
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7th International Symposium on Diffraction Structural Biology - LINXS related event โ LINXS
The 7th International Symposium on Diffraction Structural Biology will be held in Grenoble, France.
https://www.linxs.se/events/2025/05/5-7/isdsb-2025-linxs-related
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reposted by
Real Professor Moody
about 1 year ago
Thank you everyone who contributed, I will post a list later.
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