The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2

Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪 It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas doi.org/10.1093/gbe/...

How does catalysis emerge from non-catalytic domains? In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead. A striking case of catalysis evolving from binding.

🌍ProSE Online Talk 📅 Tue Sep 9 | 🕔 5pm CET How does protein sequence → structure → function really work? Prof. Nir Ben-Tal will show how AI (CLSS) is reshaping our view of the protein universe and uncovering hidden evolutionary design. 🚀 Don’t miss this! Registration: tinyurl.com/prose-seminar2

The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space". Date: September 9 Time: 5pm CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #mevosky

Join us for the next ProSE Seminar! We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients" Date: June 10 Time: 4PM CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #MEvoSky

We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA" May 13, 4PM CET Registration link: tinyurl.com/prose-seminar4 Please share!

🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology

🧬 New research reveals that encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These **alternative proteoforms** expand protein function bypassing genetic constraints. 🔗 Check it!: www.biorxiv.org/content/10.1... #Proteomics #CentralDogma #Translation

The ProSE seminar series is organized by @zachary-ardern.bsky.social, @lacholt.bsky.social, @caro-rocha.bsky.social a.bsky.social, @hassanzaman.bsky.social and me

The ProSE seminar series is organised by @claudiaalcar.bsky.social @hassanzaman.bsky.social @lacholt.bsky.social @caro-rocha.bsky.social & me - do reach out with any questions or suggestions!

New seminar series! Join us to explore how protein structures evolved! Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫 ProSE launches one day before Darwin's day! 📅 Feb 11, 3PM GMT 🔗https://tinyurl.com/prose-seminar1

Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪 Next up: Andrei Lupas “Highly repetitive genomic ORFs: a source of new fibrous proteins?” 11th February | 3 PM GMT 🔗 Register here: tinyurl.com/prose-seminar1

Co-organized by Md. Hassan Uz-Zaman, @zachary-ardern.bsky.social , @claudiaalcar.bsky.social , @caro-rocha.bsky.social & me.