One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs Two amazing keynotes: Ruslan M. Medzhitov & Joanna Wysocka #assembloids #organoids

Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research! We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees If interested, complete the form at the link below

Stem cell-derived neural organoids and assembloids are opening new frontiers in neuroscience, but what are the ethical and societal challenges? Join the discussion at a meeting supported by @danafoundation.bsky.social and @brainorganogenesis.bsky.social. 🎟️ sto.stanfordtickets.org/ethical-and-...

Check out the latest work on assembloids out in Science today 👇

Newest work in our Center 👇

Sharing today the latest from our lab, just published in Nature Biomedical Engineering. As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.

Check out this exciting new meeting at Asilomar !

Congratulations Massimo!

A few weeks ago, I talked to @neildegrassetyson.com on his StarTalk Radio about our efforts to understand human brain disorders with stem cell models including #assembloids. We touched on the promise of these technologies, the challenges & the mission behind the work www.youtube.com/watch?v=HEBj...

Congratulations, XiangLing! And thank you for all your contributions to our Center and the international courses 🙏

Exciting week for us here in the Center hosting students from all over the world!

Check out this overview of human stem cell models of brain development and disease

Second day of 2025 Stanford Brain Organogenesis is on full steam! 🚂 @rebeccalevymdphd.bsky.social @sergiuppasca.bsky.social @brainorganogenesis.bsky.social

Great summary on @npr.org by Jon Hamilton discussing the recent reconstruction of the sensory neural pathway in #assembloids reported this week by our Director @sergiuppasca.bsky.social lab at @stanfordmedicine.bsky.social www.npr.org/sections/sho...

The @sergiuppasca.bsky.social group functionally assembled the essential components of the human sensory pathway in a compound organoid "assembloid." The model could accelerate our understanding of sensory circuits and facilitate therapeutic development. ow.ly/BZ4R50VxSfy 🧪 @gregscherrer.bsky.social

Great overview of the recent @nature.com article from the Pasca lab

Exciting new research today in @nature.com from @sergiuppasca.bsky.social’s lab

Check out this brief summary

Congratulations to our Director @sergiuppasca.bsky.social for his induction into the American Institute for Medical and Biological Engineering @aimbe-official.bsky.social this week in Washington DC!

Congratulations on this important group effort!

Following an initial effort to reach consensus on the nomenclature, we gathered a group of researchers and, for over a year, we worked to outline a framework that can apply to neural #organoids and #assembloids and their xeno-transplantation. A summary of our recommendation can be seen here:

Exciting new conference!

Exciting times for human neurobiology!

Looking forward to this visit at @ox.ac.uk

First conference on #assbloids to take place later this year! 🙂

Record number of applicants for ou course! With hundreds of applicants this is almost as competitive as a top graduate program. Now the work begins to select participants and prepare the hands-on experiments. Course directed by the amazing Rebecca Levy @merveavar.bsky.social & Sabina Kanton

The CSHL conference on neural stem cell models & development coincides this year with the publication of a consortium effort in Nature. This article outlines a framework for experiments with #organoids, #assembloids from QC of pluripotent stem cells to characterizing cells in vitro & in vivo.

Please share this amazing training opportunity

Exciting event coming up!

Congratulations to Professor Pasca @sergiuppasca.bsky.social for receiving the Schaller Award in Translational Neuroscience! @stanfordmedicine.bsky.social

New hands-on course in our Center 👇👇👇

Midline Assembloids Reveal Regulators of Human Axon Guidance https://www.biorxiv.org/content/10.1101/2024.06.26.600229v1

Assembloids have emerged as a powerful tool for studying previously inaccessible processes of development and tissue homeostasis. In our article in Cell Stem Cell, we summarize advances in the generation & application of neural and non-neural #assembloids to explore complex cell-cell interactions.

This spring, we reported in Nature a therapeutic approach for Timothy syndrome This has been a long journey starting with making hiPS cell-derived neurons in 2D cultured 15 years ago when I was a postdoc & continued with creating in the lab #organoid and then #assembloid models of this disease

Exciting times for understanding human brain development!

Basic and clinical science of #neurological and #psychiatric disease: models, mechanisms and therapeutics go.bsky.app/Mm2x4AP

Starting to reshare some of lab work Recently we introduce human neural loop #assembloids created from 4 parts derived from stem cells to study the cortico-striato-midbrain-thalamo-cortical pathway and to model neurodevelopmental disease Check the emergent synchronized activity after 200 days