We are excited to announce our most recent preprint “Single-cell long-read sequencing of the experience-induced transcriptome” (www.biorxiv.org/content/10.1...) led by @sheridan in collaboration with Richard Huganir. A few highlights:

Here's the White House's proposed reorganization of NIH institutes & budgets. Details in: www.hhs.gov/sites/defaul...

Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler that I've been working on during my postdoc in the Heng Li lab (@lh3lh3.bsky.social). myloasm-docs.github.io

Telomere-to-telomere genome sequences of six ape species: chimpanzee, bonobo, gorilla, Bornean & Sumatran orangutan, & siamang! Invaluable resource for future evolutionary studies of humans & our closest living relatives. Kateryna Makova, @aphillippy.bsky.social, Evan Eichler & co in @nature.com.🙌🧬🧪

Long reads such as @nanoporetech.com or @pacbio.bsky.social can provide insights into epigenetic. We @yileifu.bsky.social & @timp0.bsky.social )summarize the latest #Bioinformatics approaches & why this matters! Out now @natrevgenet.bsky.social at: bit.ly/4cjxUtl @bcmhouston.bsky.social @jhu.edu

We summarized state-of-the-art computational methods for DNA methylation analysis using long-read sequencing, covering everything from base calling to sample-level, cell-type-level, and even population-scale analysis. Huge thanks to @sedlazeck.bsky.social and @timp0.bsky.social for this great work!

The abstract deadline for Biology of Genomes is a month away. We hope to see you there! meetings.cshl.edu/meetings.asp...