Yes, Tregs finally getting the spotlight they deserve! 🙌

“You are here to learn to ride a bicycle, not to invent a bicycle.” "Now, I’m about to establish my own research group. I feel ready to design and invent my own bicycle. I’ll remind my trainees that their job, first and foremost, is to learn how to ride." www.science.org/content/arti...

Monoclonal antibodies 50 year anniversary!

New science out from our group! This time on autoantibody specifities in juvenile idiopathic arthritis #JIA #immunosky #medsky. @uniuef.bsky.social It is well known that antinuclear antibodies (ANAs) are prevalent in JIA patients, but the actual autoantigen targeted has remained elusive.

New results on the role of circulating T follicular (cTfh) and T peripheral helper (cTph) cells in type 1 diabetes out at @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/... #immunosky #T1D #autoimmunity

Vaccines are rigorously tested, they are effective, and they save lives. More than 150 million lives have been saved in the past 50 years thanks to vaccines! But you may be worried about what's in them? So, let’s break it down ⬇

Interested in translational human immunology? We are currently recruiting a PhD student or a post-doc to work on an exciting project to to study immune changes leading to the development of type 1 diabetes. #immunosky #sciencejobs uef.varbi.com/en/what:job/...

Multiple recent studies, including 3 impressive natural experiments, consistently show a link between Shingles vaccines and reduced dementia. This week a nationwide S Korea study added a reduction of cardiovascular events My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...

More data is emerging that one shot of HPV vaccine is already efficient for protection, and boosters would not be needed. This change could both help increase vaccine compliance and reduce costs, both of which could increase HPV vaccine coverage globally.

CMV infection appears to improve anti-PD1 therapy efficacy and reduce the risk of immune-mediated toxicity of the therapy. CMV may have positive immunomodulatory effects, as evidenced also by previous reports suggesting a protective effect on development of autoimmune diseases like T1D and MS.

Are you a professor or assistant professor level researcher in the US or elsewhere outside of Finland? Looking for new opportunities in an inspiring and well-connected research environment? Finland might be just the place for you. Reach out to Finnish universities to explore what’s possible.

Gather 'round Bluesky, while I tell the hoary tale of epidemic vs. endemic. How can it be that pandemic interventions that were vitally important in 2020 are marginally effective in 2025? Science will give us the answers! Follow me... 1/

A major paper @nature.com this week found a significant decline in dementia after an outdated Shingles vaccine. I've reviewed the study and many other relevant ones here erictopol.substack.com/p/the-shingl...

Amazing study showing protective effect of herpes zoster vaccination against dementia with interesting sex differences @sexdiffimmunity.bsky.social #vaccines work! #immunosky #medsky

Highly interesting study, which suggests that Shingles vaccine could reduce dementia risk in the elderly. Possible mechanistic explanations include the role of subclinical VZV reactivations causing neuroinflammation and/or the vaccine having a bystander effect to suppress neuroinflammation.

Remember: Finland is the happiest country.

Check out our interactive timeline of some of the most devastating infectious diseases in history, alongside major advances in science and medicine that have helped control and prevent them. In English, Welsh, Gaelic, Irish, German and Spanish. 🦠🧫🔬💉 #CelebrateVaccines

Extremely grateful to @sigridjuselius.bsky.social for continuing support of our research on the #immunology of #type1diabetes!

openRxiv has arrived! We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openrxiv.org/introducing-... #openRxiv #OpenScience #Preprints #bioRxiv #medRxiv

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

And these cells are key features in imflammageing. Very cool.

Some learnings about our immune system from Covid @nature.com —importance of T cells (not just neutralizing antibodies) —key role of interferons, the first line of defense —hybrid immunity —underpinnings of Long Covid www.nature.com/articles/d41...

Another great episode on mythbusting the penicillin allergy! 🦠🧬🧪🧫 #Medsky #ImmunoSky open.spotify.com/episode/5D5q...

Starting my transition to the hopefully more rational side of the social media...