Another week, another #TylerTuesday! This Tuesday, Tyler is knocking out mesothelin in his tumor models. Good luck, Tyler!

Congrats to PhD CANDIDATE John Zhu for passing his oral qualifying exams today! Proud of you, John!

Guess What Day It Is #TylerTuesday

Happy #TylerTuesday everyone! Hope you're all having a great week🫀

ICYMI: SSRIs Elevate Intratumoral Serotonin and Enhance Antitumor Immunity, a #ResearchWatch summary of a new study by Dr. Bo Li, @liliyanglab.bsky.social, and colleagues at @dgsomucla.bsky.social @uclastemcell.bsky.social aacrjournals.org/cdnews/news/...

It's #TylerTuesday!!

Congratulations to Sean Shen for passing his oral qualifying exams and becoming a PhD Candidate! We're proud of you, Sean!

It's #TylerTuesday! Last week PhD Candidate Tyler Halladay shared his research on Engineering iPSC-derived gdT cells for solid tumor therapy with his UCLA Pharmacology community. Thanks for being a great representative of our lab, Tyler!

Congrats to Dr. Bo Li and James Elsten-Brown on earning second place in UCLA TDG's #LABEST2025 poster competition for their work on SERT regulation of serotonin-dependent antitumor immunity, based on their research in doi.org/10.1016/j.ce... Way to go, boys!

This #WorldOvarianCancerDay, we highlight the work of Dr. Sanaz Memarzadeh and Dr. Lili Yang, who have teamed up to develop a novel immunotherapy they hope will transform ovarian cancer treatment. ➡️ bit.ly/3XsEVBS

A UCLA study suggests that common antidepressants could enhance the immune system’s ability to fight #cancer and suppress tumor growth. Repurposing these existing FDA-approved drugs could speed up the process of bringing new cancer treatments to patients. stemcell.ucla.edu/news/common-...

UCLA researchers led by Dr. Lili Yang have discovered a promising new method to treat myeloid malignancies, a group of blood cancers, using off-the-shelf CAR-NKT cells. Learn more this #WorldCancerDay how this study could improve patient outcomes: bit.ly/4hLW0yf

Lili Yang, UCLA leverages the power of hematopoietic stem cells to generate CAR-NKT for immunotherapy Harnessing Stem Cells for Off-The-Shelf CAR-NKT Cell Therapy

Now online! Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

I’m a very lucky person 👍

‼️ @uclaupdates.bsky.social Reports: Who's the team behind identifying serotonin transporter as a tumor immunotherapy target? Dr. Bo Li leads a team of post-docs, grad students and undergrads in identifying immune checkpoints. And of course our lab manager Jie Huang! newsroom.ucla.edu/stories/anti...

Can serotonin and SSRIs help T cells kill cancer? Our @cp-cell.bsky.social article by Dr. Bo Li, doctoral candidate James Elsten-Brown and their team reports "Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis!" www.cell.com/cell/fulltex...

Dr. Yan-Ruide Charlie Li and our doctoral students Yichen John Zhu and Yuning Christine Chen cover "The clinical landscape of CAR-engineered unconventional T cells" and the amazing therapeutic potential it holds in their review for @cp-trendscancer.bsky.social doi.org/10.1016/j.tr...

Doctoral students Ying Fang and Yuning Christine Chen and their team discuss the promising "Biological functions and therapeutic applications of human mucosal-associated invariant T cells" in their review for @biomedcentral.bsky.social Journal of Biomedical Science doi.org/10.1186/s129...

Dr. Yan-Ruide Li, Ying Fang, and their amazing teammates report their therapeutic innovations in "Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies" in their article for @natcomms.nature.com doi.org/10.1038/s414...

Our amazing post-docs and doctoral students have made breakthroughs in "Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture", as shown in @nature.com Protocols doi.org/10.1038/s415...

Exciting developments in the field of CAR-T therapies and the strategies to enhance it. Dr. Yan-Ruide Li and his team walk us through the state of the field and its promising future in their review on "Boosting CAR-T cell therapy through vaccine synergy" doi.org/10.1016/j.ti...