🧪 DISCOVERY! A new oligonucleotide inhibitor of APOBEC3A with single-digit nanomolar Ki was developed by BMB members, @jwattsgroup.bsky.social , and others! Check it out in @narjournal.bsky.social pubmed.ncbi.nlm.nih.gov/40156866/

🧪 Looking to gain a fundamental understanding of the field of paternal inheritance and sperm epigenetics? Check out this review by @epididymosome.bsky.social pubmed.ncbi.nlm.nih.gov/40163890/

✅ ID new citrullination site in NF-kB p65 ✅ Show macrophage polarization is decreased when citrullination enzyme PAD2 is gone ✅ Develop a nanomedicine: gold nanoparticles + PAD2 inhibitor + ICAM-1 ✅ Show reduction of inflammation in acute lung injury syndrome 🧪 pubmed.ncbi.nlm.nih.gov/40087815/

🧪 Finally!!! A single-cell atlas of the mouse seminal vesicle!!! (seriously though, it just might be the last major mammalian organ to undergo single cell sequencing). Check it out! pubmed.ncbi.nlm.nih.gov/40036847/#fu... @arturmansl.bsky.social @anashin.bsky.social @epididymosome.bsky.social

🧪 Working to develop #drugs to treat #chikungunya ? Check out new fluorogenic substrates that help read out viral protease activity, developed by @tulsiupadhyay.bsky.social @westberglab.com @eunayoo.bsky.social @michaelzlin.bsky.social et al! pubmed.ncbi.nlm.nih.gov/39981948/

Sean Ryder, PhD, professor of biochemistry & molecular biotechnology, makes the case for NIH funding in this editorial: direc.to/mMoW “Gutting the NIH will harm those who stand to benefit from new, lifesaving therapies derived from NIH-funded research.” #NIHfunding @umasschan-bmb.bsky.social

#Transposons are parasitic genetic elements that act as raw material for evolution of new functions. @briankelch.bsky.social &co show that the capsid of the #virus-derived retrotransposon Copia mediates synaptic plasticity at the #Drosophila neuromuscular junction 🧪 @plosbiology.org plos.io/3X71IDa

Check out this video (not ours) to learn more about what indirect costs (F&A costs) are and why they MUST be preserved. Then please contact your representatives to protect funding for science and healthcare! #science #research #indirectcosts #nih www.youtube.com/watch?v=yxTD...