@alanhschulman.bsky.social
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Happy to have been a part of the worldwide effort to assemble a pan-genome and pan-transcriptome for oat! A great cereal crop with lots of health benefits. We hope this resource will advance oat quality improvement, resilience, and sustainability as well as provide a foundation for basic research.
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A pangenome and pantranscriptome of hexaploid oat - Nature
A pangenome of oat, assembled from 33 wild and domesticated oat lines, sheds light on the evolution and genetic diversity of this cereal crop and will aid genomics-assisted breeding to improve product...
https://www.nature.com/articles/s41586-025-09676-7
3 days ago
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Watson's troubling B-side
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4 days ago
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Their longevity I've wondered about for a long time. Harder to decipher the lifespan of the Greenland Shark, maybe 500 yr.
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about 1 month ago
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A mechanism that I and certainly many others have wondered about has now been revealed.
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about 1 month ago
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Happy International Coffee Day. Here is a new EFSA study, but don't lose sleep over it.
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about 1 month ago
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Who would have guessed? Why it's worth exploring the various branches of the tree of life.
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about 2 months ago
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reposted by
Etienne Bucher 🌾🧬🇪🇺
about 2 months ago
How about we call genome edited crops "barely mutant"? Seems to be a nice workshop below btw!
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The perfect cacio e pepe, how to stop shoe odor, and zebra-stiped cows!
arstechnica.com/science/2025...
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Meet the 2025 Ig Nobel Prize winners
The annual award ceremony features miniature operas, scientific demos, and the 24/7 lectures.
https://arstechnica.com/science/2025/09/meet-the-2025-ig-nobel-prize-winners/
about 2 months ago
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reposted by
Journal of Experimental Botany
about 2 months ago
🫛 SPECIAL ISSUE REVIEW 🫛 Johansson et al. ✍️ Redox-active molecules such as ROS, RNS, and RSS orchestrate legume responses to diverse (a)biotic stresses and symbioses, offering novel strategies to enhance crop resilience in changing environments. 🔗
doi.org/10.1093/jxb/...
#PlantScience
🧪
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Heads up on this one.
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2 months ago
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Nice to see a genome assembly emerge for this barley wild relative. Hopefully, we'll learn how to improve barley's drought tolerance while maintaining yield.
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2 months ago
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reposted by
STAT
3 months ago
"I’ve never heard as many colleagues saying things like 'CDC is dead’ as I have today," an agency employee told STAT.
www.statnews.com/2025/08/28/c...
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Crisis within CDC is spilling into real world, experts say
"I’ve never heard as many colleagues saying things like 'CDC is dead’ as I have today," an agency employee told STAT.
https://www.statnews.com/2025/08/28/cdc-crisis-what-next-public-health/?utm_source=bluesky&utm_campaign=bluesky_organic&utm_medium=social
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reposted by
Dennis Goris
3 months ago
I miss the old brand
#CDC
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reposted by
Theoretical and Applied Genetics
3 months ago
Pangenome reveals structural variant-driven variation in expression of in winter oilseed rape. Framework enables population-scale SV-eQTL discovery beyond traditional SNP-based approaches - major advance for functional genomics. Read more here:
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Graphical pangenomics-enabled characterization of structural variant impact on gene expression in Brassica napus
https://rdcu.be/evKlC
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reposted by
Marc Somssich
3 months ago
New Zealand had some of the most restrictive laws when it came to genetically engineered food crops. This move once again demonstrates how the NZ Government makes Science-based decisions. Take note, European Union!
#PlantGMOs
#PlantNGTs
#PlantScience
#Agroculture
#Sustainability
#PlantBreeding
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Really interesting to see this systematic and broad study on an important leaf trait.
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3 months ago
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The campaign against science by the Trump administration through grant slashing has reached FlyBase. There is an effort to crowd-fund this vital database:
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3 months ago
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Happy to announce our current scan of the risk environment for NGT (gene editing) in animals, just published today.
doi.org/10.2903/j.ef...
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https://doi.org/10.2903/j.efsa.2025.9566
3 months ago
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Interesting aspect to ABA: the role of poly-ubiquitination and mono-ubiquitination to post-transcriptionally regulate ABA receptors
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4 months ago
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reposted by
Eric Topol
4 months ago
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
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5 months ago
DNA virus infections shape transposable elements activity in vitro and in vivo
doi.org/10.1101/2024...
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DNA virus infections shape transposable elements activity in vitro and in vivo
Transposable elements (TEs) are implicated in a variety of processes including placental and preimplantation development and a variety of human diseases. TEs are known to be activated in the context o...
https://doi.org/10.1101/2024.04.18.589901
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Hot off the press: our analysis of the proposed EU limits to NGT1 category of genome editing in light of recent data on genomic diversity.
onlinelibrary.wiley.com/doi/10.1111/...
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Proposed EU NGT legislation in light of plant genetic variation
The European Commission (EC) proposal for New Genomic Techniques (NGTs) of July 2023 specifies that Category 1 NGT (NGT1) plants, which are considered equivalent to conventional plants, that is those...
https://onlinelibrary.wiley.com/doi/10.1111/pbi.70228
5 months ago
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reposted by
Thomas Zimmer
6 months ago
This bizarre rejection of health science is not incidental: MAGA represents a raging revolt against the very foundations of modern society which are roundly rejected as illegitimate impositions and a personal affront to the prerogative of the MAGA patriarch to decide what is true and what is real.
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Even given possible response bias, this is pretty shockingly high.
www.nature.com/articles/d41...
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75% of US scientists who answered Nature poll consider leaving
More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.
https://www.nature.com/articles/d41586-025-00938-y
7 months ago
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reposted by
Alexandra Witze
7 months ago
Nature reporters' ongoing coverage of Trump 2.0 impacts on science and scientists is collected here:
www.nature.com/collections/...
Reach me at alexwitze.01 on Signal, or witzescience[at]gmail.com, with tips, feedback, follow-ups, anything we should be covering, etc.
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How Trump 2.0 is reshaping science
Since US President Donald Trump took office in January 2025, his team has made major changes to the federal government that have disrupted research and ...
https://www.nature.com/collections/jcjhabjhgi
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Despite dire predictions, we're not there yet. But it's a cute beast and makes great copy.
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7 months ago
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This will have far-reaching and negative consequences for everyone. When it comes to pandemics, what goes around certainly comes around.
www.nytimes.com/2025/03/26/h...
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H.H.S. Scraps Studies of Vaccines and Treatments for Future Pandemics
Federal officials cited the end of the Covid-19 pandemic in halting the research. But much of the work was focused on preventing outbreaks of other pathogens.
https://www.nytimes.com/2025/03/26/health/future-pandemics-vaccines-funding.html?smid=nytcore-android-share
8 months ago
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reposted by
Needhi Bhalla 💅🏽
8 months ago
For a presentation I am giving, I made a wordcloud of the titles of the NIH grants that were canceled. It is clear about the unscientific goals of this administration
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If you are a member of the UK or international scientific community, you can sign the open letter from this link.
docs.google.com/forms/d/e/1F...
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Open letter to the President of the Royal Society – time to stand up for your values
If you wish to show your support for the letter below regarding apparent inaction by the Royal Society in the face of breaches of its code of conduct by Elon Musk FRS, please sign below. I invite anyo...
https://docs.google.com/forms/d/e/1FAIpQLSfxqRCQJd8jNnNdXOmR7Ii3AvmO211SX76ai69LpbMHIWkfbA/viewform
9 months ago
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reposted by
Richard Sever
9 months ago
"Pressure growing on the Royal Society to expel Musk after more >1000 scientists sign open letter"
www.theguardian.com/science/2025...
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Royal Society urged to expel Elon Musk as fellows sign open letter
More than 1,700 academics complain about X owner’s behaviour, citing his ‘assault on scientific research’
https://www.theguardian.com/science/2025/feb/14/elon-musk-royal-society-open-letter-academics
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A warning from Harold Varmus about the consequences of the current American administration's dismantling and hobbling of research as well as public health measures in the US and worldwide. Where is the protest of this?
bit.ly/42WGfAE
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Opinion | American Science is Under Attack (Gift Article)
The Trump administration hobbles research and endangers the public health.
https://bit.ly/42WGfAE
9 months ago
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Difficult to speak Truth to Power when Power tries to gag the speakers. The National Nature Assessment seems to contain facts that Trump would like to suppress.
bit.ly/417N8xu
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Trump Killed a Major Report on Nature. They’re Trying to Publish It Anyway. (Gift Article)
The first full draft of the assessment, on the state of America’s land, water and wildlife, was weeks from completion. The project leader called the study “too important to die.”
https://bit.ly/417N8xu
9 months ago
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Well, the Freeze has been unfrozen, and grant money will flow for now. The idea was to put Woke to sleep, but instead many researchers woke up, wondering what to do about their impending flight and conference or the reagents they needed for an ongoing experiment.
www.bbc.com/news/live/cw...
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White House rescinds memo on Trump order to freeze federal grants and loans - live updates
Donald Trump's team say the pause in some federal assistance still applies, but the withdrawal of the memo has sparked further confusion.
https://www.bbc.com/news/live/cwyw5l584knt
10 months ago
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Heterodichogamy or alternate dioecy, or serial transgenderism, in more common parlance, well that's just nuts! And it's now finally understood.
www.science.org/doi/10.1126/...
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Ancient structural variants control sex-specific flowering time morphs in walnuts and hickories
Balanced mating type polymorphisms offer a distinct window into the forces shaping sexual reproduction strategies. Multiple hermaphroditic genera in Juglandaceae, including walnuts (Juglans) and hicko...
https://www.science.org/doi/10.1126/science.ado5578
10 months ago
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Certainly gets the creative juices flowing! Simulating 500 million years of evolution with a language model | Science
www.science.org/doi/10.1126/...
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Simulating 500 million years of evolution with a language model
More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can gen...
https://www.science.org/doi/10.1126/science.ads0018
10 months ago
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Researchers at CDC: no travel, external meetings or communications. Apparently their paymasters believe magical thinking will keep viruses at bay.
www.washingtonpost.com/health/2025/...
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Health researchers alarmed as Trump administration pauses travel, communications
The halt has frozen research grants, meetings and key health updates. “Everything is basically in chaos,” said one cancer researcher.
https://www.washingtonpost.com/health/2025/01/23/trump-administration-hhs-health-agencies-pause-travel-communications/
10 months ago
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Seen in Helsinki. I knew that viruses self-assemble, but didn't know it was also true for sandwiches. Remarkably, they can do this and experience emotion at the same time.
10 months ago
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reposted by
Marc Somssich
10 months ago
Cool graphic from KWS on the
#GenomeEditing
timeline. Impressive how few years passed between the first use of CRISPR/Cas9 in a crop plant (2013) to the first release of an edited crop (
#GABATomato
) (2021). Trad.
#PlantBreeding
can take decades! 😮
www.kws.com/corp/de/inno...
#PlantScience
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Seems to include one who published and perished, but no skeletons in the closet.
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10 months ago
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I will pod-cast this: an interesting aspect in legumes worthy of further investigation.
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11 months ago
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Low-GI rice: a great idea with potential health benefits for a large segment of the world's population.
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11 months ago
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Low GI rice: great idea with potential health benefits for a large segment of the world's population
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11 months ago
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A novel gene with significance for drought tolerance, likely formed by action of HGT and TE-driven processes, to "weird" subjects for many biologists (not me) but nevertheless the grist of evolution.
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11 months ago
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reposted by
Kevin Bird
11 months ago
A breath of fresh air to read a good opinion piece in a major newspaper
www.theguardian.com/commentisfre...
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Trump and Musk are obsessed with genetics – but there’s no science behind their simplistic views | Jonathan Roberts
The US right is misrepresenting science to support its racist agenda. There’s far more to it than ‘good’ or ‘bad’ genes, says genetic counsellor Jonathan Roberts
https://www.theguardian.com/commentisfree/2024/dec/30/donald-trump-elon-musk-genetics-science-right
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reposted by
Pam Ronald
11 months ago
A call for greater investment in research—including genebanks, breeding programs, and biodiversity-friendly farming practices. Science helps us better understand the complex relationships between biodiversity, ecosystem services, and agricultural productivity.
www.science.org/doi/10.1126/...
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Why biodiversity matters in agriculture and food systems
Imagine a world where the variety of food sources we rely on is reduced to a mere handful of species. This is not a dystopian future. It’s the path we are on right now, and it’s happening silently in ...
https://www.science.org/doi/10.1126/science.ads8197
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"Crown Shyness" is not about royal abdication but rather the tendency of apparently only some tree species to develop dissected canopies in forests. Something new for me!
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11 months ago
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A stunning illustration of what can be done with a model system.
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11 months ago
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This is a really useful approach where data is scarce or unavailable. Would be one way for tracking e.g. Syria's economic status under the current circumstances.
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11 months ago
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One Health not only needs ecological research, but major funders, e.g the EU, need to make integrated funding calls, rather than isolating Health from Climate from Agriculture and Environment in separate Pillar II Clusters, if we are to make progress.
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2413367121
11 months ago
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A warning that we should not follow Alice through the looking glass, or at least not bring back what we find there. A large working group has concluded that synthetic life with mirrored chirality would be too risky to synthesize and chance release into our biosphere.
www.science.org/doi/10.1126/...
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Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
https://www.science.org/doi/10.1126/science.ads9158
11 months ago
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