@prudenciolab.bsky.social
📤 9
📥 10
📝 3
reposted by
Wilfried Rossoll
about 1 year ago
Our proximity proteomics study introducing Probe‑dependent Proximity Profiling (ProPPr) and applying it for profiling tau pathology‑associated proteins in tauopathies +
@drneurochic.bsky.social
& others is out now!
@cziscience.bsky.social
molecularneurodegeneration.biomedcentral.com/articles/10....
loading . . .
Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies - Molecular Neurodegeneration
Background Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mec...
https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-025-00817-0
3
19
6
I was thrilled for the opportunity to present today
#ADPD2025
the work @PrudencioLab, in the wonderful city of Vienna where I was lucky to get an awesome tour by Dr Wilfried Rossoll!
@rossolllab.bsky.social
about 1 year ago
0
2
1
Our manuscript got highlighted with a beautiful infographic!
#TDP43
#PerrySyndrome
#Neurodegeneration
#RNAsplicing
#Biomarkers
#Neuroscience
#FTLD
#ALS
#PrudencioLab
DOI:
lnkd.in/eXr8te8A
about 1 year ago
0
2
1
Excited to finally publish our work on cryptic splicing in Perry syndrome. Moreover, it higlights that not all cryptic RNAs are detected in every brain region with TDP-43 pathology. Enjoy!
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
loading . . .
TDP‐43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP‐43 Proteinopathies
In Perry syndrome caudate nucleus, TDP-43 pathology and dysfunction lead to the cryptic splicing of eight RNA targets as well as HDGFL2 cryptic protein. In the substantia nigra, only one cryptic targ....
https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.30104
over 1 year ago
0
1
0
you reached the end!!
feeds!
log in
