Morning sky-friends! We are delighted to share some ‘hot off the xray’ images from our talented scientists, Dr André Mourão & Ting Deng. They produced this beautiful diffraction of a compound bound to one of our protein targets whilst working with @esrf.fr

BNMRZ Symposium Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies, November 6–7, 2025, TUM Institute for Advanced Study, Garching @ias-tum.bsky.social registration opens soon www.bnmrz.org/4dstructbiol #BNMRZ #NMRchat #NMR 🧲

#HelmholtzMunich’s BNMRZ has joined Germany’s Instruct-ERIC Centre 🔬 Instruct-ERIC provides open access to advanced structural biology technologies. #BNMRZ advances innovation in #NMR methods, drug discovery, and imaging - boosting the German Centre’s capabilities. 👉 Read more: t1p.de/pjtyv

New paper in collaboration with the Förstemann Lab & Boekhoven Lab is out! Combining #NMR & mutational analysis, we characterize the unique features of the #Ago2 IDR region which drives Ago2/RNA #condensate formation. doi.org/10.1093/nar/... @clarahipp.bsky.social

One of our group members @clarahipp.bsky.social had the great opportunity to attend the Nobel Laureate Meeting last week in sunny Lindau ☀️ #lino25

📢 Paper with @sattler-lab.bsky.social now published in @narjournal.bsky.social ! doi.org/10.1093/nar/... We combine #NMR, #SAXS, and #MD to construct conformational ensembles, showing that A-to-I hyper-editing leads to significant structural dynamics. MD simulations by @piompons.bsky.social

New preprint is out! We've looked at the interactions of Sgt1 with Hsp90 in yeast and found some surprising results! We've also shown that in the presence of clients, Sgt1 prevents aha1 binding on Hsp90 and thus increases the substrate's dwell time. #NMR #chaperone www.biorxiv.org/content/10.1...