New preprint from the lab! For those who love astrocytes 🤩. We welcome feedback! #preprint #openaccess #astrocytes #autism

Repair after CNS injury is not strictly local! We find that lesion-remote #astrocytes (LRAs) exhibit striking spatiotemporal heterogeneity across spared regions of the injured spinal cord and shape neural repair far from the injury epicenter! www.nature.com/articles/s41...

Astrocytic Sox9 overexpression in Alzheimer’s disease mouse models promotes Aβ plaque phagocytosis and preserves cognitive function www.nature.com/articles/s41...

Finally it’s here! 🌟⬇️ www.nature.com/articles/s41... I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer 1- How does the vasculature communicate with astrocytes? 2- Is this communication dependent to what happens in the body. 3- Is it relevant to human diseases?

Excited to share the latest from the lab on the molecular mechanisms of silencing and un-silencing a hippocampal engram ensemble. Was fun using a variant of the EPSILON technique developed by Adam Cohen's lab. (1/2) www.sciencedirect.com/science/arti...

New paper from the lab 🚨 Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age: authors.elsevier.com/a/1lzT-3BtfH...

Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke. www.sciencedirect.com/science/arti...

New paper from the lab led by Ali Golbabaei. If you’re interested in systems consolidation, generalization and hippocampal neurogenesis a short 🧵 follows: authors.elsevier.com/a/1lsO73QW8S...

We have a new review out in TINS! A functional perspective on astrocyte heterogeneity www.cell.com/trends/neuro...

Super interesting review on astrocyte development by @m-r-williamson.bsky.social and colleagues ! #astrocytes #glia #review

Absolutely thrilled to share the first half of my PhD work! Super proud to see it finally out! www.nature.com/articles/s41... Thread below for a quick (10 point) recap of what we found! 🧵🧪🧠

Sharing our new short review on development and diversity of astrocytes! journals.biologists.com/dev/article-...

Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...

Thought this would be a nice way to enter the bsky community👇Delighted for Katie (now in Chris Dulla's lab at Tufts). Thank you to our collaborators, to the reviewers and to Cagla Eroglu for the highlight! www.science.org/doi/10.1126/...

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n

Thrilled to announce that my lab is now open at Ohio State! We study astrocytes as gene therapy targets for brain repair after ischemic stroke and in vascular dementia, developing new viral tools along the way. If you're interesting in joining or collaborating, please reach out! gleichmanlab.com

Check out our latest paper today in Nature: “Goal specific hippocampal inhibition gates learning” www.nature.com/articles/s41... By Nuri Jeong, Xiao Zheng, Abby Paulson, Steph Prince and colleagues.

I get a lot of questions on the #NIH #K99 #postdoc to faculty transition award. Decided to pen my thoughts and experiences towards receiving the K99/R00 - hoping it would be helpful for the community. Please find article link at - debosardarlab.org/blog

⭐Christmas highlight in Cell Research! @sjo09.bsky.social and I address the idea that learning-associated astrocytes become essential members of a memory engram ensemble, shifting the neuron-centric view of memory function. Big shoutout to @m-r-williamson.bsky.social! www.nature.com/articles/s41...

Do you think you’ve conquered the enigma of the memory engram? News flash: You’re only scratching the surface. :) In our latest work (led by @Clement), we dissected the engram to uncover what information is processed during encoding and becomes the essence of the recalled memory.

For my first post here: excited to share our new work out in Nature! Learning-associated astrocyte ensembles regulate memory recall www.nature.com/articles/s41...

Congrats to the team! Here we directly image and quantify cerebral #angiogenesis and pruning in vivo. Found interesting regional differences and dependence on #notch signalling. Where you look does matter! www.cell.com/cell-reports...

For my first post here: excited to share our new work out in Nature! Learning-associated astrocyte ensembles regulate memory recall www.nature.com/articles/s41...

xcited to share our new results! We (huge team effort led by post-doc extraordinaire Sylvie Lesuis) examined the effects of acute stress on threat memory generalization and engram ensemble architecture. www.sciencedirect.com/science/arti...