Elaine Chen
@elaineywchen.bsky.social
📤 2641
📥 126
📝 51
Reporter
@statnews.com
covering drugs and the biopharma industry | signal: elaineywchen.70
reposted by
Elaine Chen
Jonathan Wosen
about 1 month ago
I'm a science journalist for
@statnews.com
looking to talk with folks who applied to biomedical Ph.D. programs and had offers rescinded earlier this year. What have you been up to since then? You can reach me at
[email protected]
or via Signal (username jwosen.27).
#journorequest
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Latest: A race to develop a new class of narcolepsy drugs could not only transform treatment for patients with the rare sleep disorder, but also many people with common health conditions like Alzheimer's and depression who struggle to stay awake
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Drugmakers are racing to help patients stay awake — and could also make billions
A race to develop a new class of drugs could transform treatment for patients with narcolepsy — as well as for patients with other conditions that cause them to struggle to stay awake.
https://www.statnews.com/2025/07/22/narcolepsy-treatment-orexin-trials-future-of-wakefulness-drugs/
2 months ago
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reposted by
Elaine Chen
Jason Ukman
3 months ago
Novo Nordisk, seen as lagging in obesity drug race, says it’s playing the long game. Via
@elaineywchen.bsky.social
www.statnews.com/2025/06/25/n...
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Novo Nordisk, seen as lagging in obesity drug race, says it’s playing the long game
Novo Nordisk is seen as having fallen behind in the race for new obesity drugs. It argues it is playing the long game.
https://www.statnews.com/2025/06/25/novo-nordisk-obesity-drugs-strategy-readouts/
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From
#ADA25
: Full results suggest Novo's CagriSema is comparable to Lilly’s Zepbound on safety and efficacy Weight loss looks to be plateauing at the end of late-stage studies, raising Qs around how much more weight patients can lose on the drug
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Novo Nordisk’s amylin obesity drug keeps performing like Zepbound
Novo Nordisk’s next-gen weight loss drug and Zepbound “seem fairly equal to me,” one expert says after release of new late-stage results for CagriSema.
https://www.statnews.com/2025/06/22/novo-nordisk-cagrisema-weight-loss-drug-comparison-eli-lilly-zepbound-investors-disappointed/
3 months ago
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Latest from
#ADA25
: Novo's injectable amycretin showed substantial weight loss in an early study, but similar efficacy across different doses and high rates of side effects raise questions about which dose Novo will pursue going forward
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Full data on Novo Nordisk’s new amylin drug raise dosing questions
Results for weight-loss drug targeting amylin find similar efficacy across different doses and high rates of side effects, raising questions about which dose Novo will pursue.
https://www.statnews.com/2025/06/20/novo-nordisk-weight-loss-drug-amylin-hormone-injection-effective-but-side-effects-an-issue/
3 months ago
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reposted by
Elaine Chen
Alex Hogan
3 months ago
New video- my new
@statnews.com
colleague
@chelseacirruzzo.bsky.social
and I chat about RFK Jr.'s dismissal of all the members of ACIP, CDC's vaccine advisory board. Also I'm going to be doing a video every week now so please wish me luck (and like & subscribe plz)
youtu.be/brVDswDpaeQ
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Did RFK Jr. break a promise he made to GOP Senator?
YouTube video by STAT
https://youtu.be/brVDswDpaeQ
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LATEST: A conservative culture cost Novo Nordisk its lead in the obesity drug race, former employees told me It wanted to tread carefully as the first mover in the space, and its belief in Ozempic/Wegovy blinded it to other candidates, they said
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A cautious culture cost Novo Nordisk its lead in the obesity drug race, former employees say
Novo Nordisk’s stock has tumbled over 50% since its peak around a year ago, and it just ousted its CEO. Former employees say the company's cautious culture is to blame.
https://www.statnews.com/2025/06/05/novo-nordisk-weight-loss-drugs-market-dominance-slips-eli-lilly-gains-here-is-why/
4 months ago
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reposted by
Elaine Chen
Isabella Cueto
4 months ago
Yesterday, we dove into all the data on chronic disease in the U.S. So, what can actually make a dent in it? Here are 3 big ideas:
www.statnews.com/2025/05/21/r...
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Three big ideas to actually ‘Make America Healthy Again’
STAT reviewed dozens of studies, interviewed chronic disease experts, and landed on three focus areas for Robert F. Kennedy Jr. to boost health.
https://www.statnews.com/2025/05/21/rfk-jr-chronic-disease-maha-commission-experts-focus-three-key-target-areas/
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reposted by
Elaine Chen
Isabella Cueto
4 months ago
NEW: How RFK Jr. goes about solving the chronic disease epidemic depends on his top concerns. Here, we break down the nation's health into 9 "priorities" — using original data analysis you can't find elsewhere! — and let you choose yours. W/
@jaspar.bsky.social
:
www.statnews.com/2025/05/20/k...
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RFK Jr. declared war on chronic disease. First comes the battle over priorities
How would you solve the chronic disease epidemic? Here's STAT's extensive new data analysis, and nine ways to tackle the problem.
https://www.statnews.com/2025/05/20/kennedy-maha-commission-report-chronic-disease-new-data-how-to-prioritize/
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The explosion of compounded GLP-1 offerings is ending, and many patients are left with no good options. Telehealth companies and compounders are pursuing workarounds that may be riskier. At the same time, patients still can't afford the branded drugs. w/
@katiepalmer.bsky.social
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The end of compounded GLP-1 copies leaves many patients in a ‘lose-lose’ position
With GLP-1 shortage officially over, patients who relied on compounded copies have only bad options to choose from
https://www.statnews.com/2025/04/29/compounded-glp-1-drugs-patients-seek-semaglutide-alternatives-wegovy-zepbound-mounjaro/
5 months ago
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reposted by
Elaine Chen
Megan Molteni
5 months ago
WaPo has the numbers on those NIH advisory board purges
@jasonmast.bsky.social
and I first reported on last month. Six percent of White males who serve on boards were fired, compared with half of Black and Hispanic females and one-quarter of all females, according to an analysis by board chairs.
add a skeleton here at some point
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reposted by
Elaine Chen
Alex Hogan
6 months ago
What do the Trump administrations tariffs mean for the pharmaceutical industry? New short vid
@statnews.com
h/t to my STAT colleagues
@elaineywchen.bsky.social
and Ed Silverman
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RFK Jr. vowed to promote “radical transparency” at HHS. But today the dpt made major cuts to teams across its agencies that handle communications, media relations, and FOIA requests - w/
@lizzylawrence.bsky.social
,
@isabellacueto.bsky.social
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After RFK Jr.’s ‘radical transparency’ pledge, HHS shutters much of its communications, FOIA operations
After health secretary RFK Jr.’s ‘radical transparency’ pledge, HHS has shuttered much of the agency's communications and FOIA operations.
https://www.statnews.com/2025/04/01/hhs-rfk-job-cuts-communications-foia-operations/
6 months ago
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reposted by
Elaine Chen
Isabella Cueto
6 months ago
HHS workers affected by today's announcement/ RIF: Tell us what's going on! You can do so confidentially/anonymously through this form. I'm also at isabellacueto.03 on Signal, or send a DM.
www.statnews.com/2025/03/27/h...
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Are you affected by the HHS cuts and restructuring?
HHS is set to cut 10,000 jobs and consolidate divisions — have you been affected? @statnews would like to hear from you.
https://www.statnews.com/2025/03/27/hhs-cuts-restructuring-reader-form/
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reposted by
Elaine Chen
Jason Ukman
6 months ago
New: The NIH has canceled funding for a landmark diabetes study — at a time when RFK Jr. and the rest of the MAHA movement is focused on addressing chronic diseases, including diabetes. Smart story from
@elaineywchen.bsky.social
www.statnews.com/2025/03/17/t...
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NIH cancels funding for landmark diabetes study at a time of focus on chronic disease
The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said.
https://www.statnews.com/2025/03/17/trump-cuts-columbia-university-nih-cancels-diabetes-prevention-program-study/
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reposted by
Elaine Chen
Lizzy Lawrence
6 months ago
Weldon out as CDC nominee, hours before he was set to appear in front of the Senate:
www.statnews.com/2025/03/13/t...
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White House pulls nomination of Dave Weldon as CDC director hours before hearing
The White House has pulled the nomination of Dave Weldon as CDC director hours before heh was set to appear for his confirmation hearing.
https://www.statnews.com/2025/03/13/trump-administration-withdraws-dave-weldon-cdc-nomination/
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reposted by
Elaine Chen
Bob Herman
6 months ago
Eli Lilly's obesity and diabetes drugs are paying off for top executives. CEO Dave Ricks took home $114 million last year, and he and other leaders also were treated to a "leadership meeting" at last summer’s Olympics in Paris. More w/
@elaineywchen.bsky.social
:
www.statnews.com/2025/03/11/e...
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Eli Lilly’s Dave Ricks takes home $114 million as obesity drugs fuel company’s fortunes
Eli Lilly’s rising fortunes tied to its weight loss and diabetes drugs led to a nine-figure payday for its top executive.
https://www.statnews.com/2025/03/11/eli-lilly-dave-ricks-compensation-paris-olympics/
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reposted by
Elaine Chen
Isabella Cueto
7 months ago
Breaking: RFK Jr. moves to quietly eliminate public comment from HHS's decision making:
www.statnews.com/2025/02/28/r...
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RFK Jr. moves to eliminate public comment in HHS decisions
HHS Secretary Robert F. Kennedy Jr. moved to rescind the longtime practice of giving the public a chance to comment on the health agency’s plans.
https://www.statnews.com/2025/02/28/rfk-jr-eliminating-public-comment-hhs-decisions-richardson-waiver/
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Pfizer yesterday revised its DEI webpage to emphasize the importance of "merit," joining other companies seeking to align with the Trump administration
@jaspar.bsky.social
and I laid out all the deletions and insertions in our story
www.statnews.com/2025/02/27/p...
7 months ago
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reposted by
Elaine Chen
J. Emory Parker 🏳️🌈
7 months ago
Incredible: we're reaching a point where new weight loss drugs might be *too* effective, leading to health risks. from
@elaineywchen.bsky.social
www.statnews.com/2025/02/20/t...
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NEW: Patients in trials of Lilly's next-gen obesity drug tell me they think they're losing too much weight. One started skipping doses, another is making himself eat caloric foods. This is part of what some see as a risky race for more weight loss
www.statnews.com/2025/02/20/t...
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How much weight loss is too much? Pharma is pushing the limit with new obesity drugs
How much weight loss is too much? Pharma is pushing the limit with new obesity drugs.
https://www.statnews.com/2025/02/20/too-much-weight-loss-in-obesity-drug-trial-market-pressure-to-outperform-wegovy-zepbound/
7 months ago
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reposted by
Elaine Chen
O. Rose Broderick
7 months ago
Looking to talk with federal employees with disabilities who were terminated this weekend, especially folks hired through Schedule A or disabled veterans. Please boost!
#disability
#journorequest
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reposted by
Elaine Chen
Lizzy Lawrence
7 months ago
Scoop: The cuts to FDA included head of medical device safety Rusty Segan. He was hired in September after a lengthy search by the agency.
www.statnews.com/2025/02/18/f...
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FDA’s head of device safety among employees terminated in 'challenging' weekend
The cuts hit the FDA's medical device center particularly hard, including reviewers and experts on AI-enabled medical technology.
https://www.statnews.com/2025/02/18/fda-trump-musk-doge-cuts-ross-segan-memo-medical-device-safety/
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reposted by
Elaine Chen
Lizzy Lawrence
7 months ago
The Trump administration terminated employees at the Food and Drug Administration on Saturday night, three sources told STAT. If you were affected or know more about the layoffs, feel free to message me on Signal at lizzylaw.53
www.statnews.com/2025/02/15/t...
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Trump administration lays off FDA employees
The cuts are part of a purge of 5,200 probationary workers across federal health agencies that started Friday.
https://www.statnews.com/2025/02/15/trump-job-cuts-fda-hhs-doge/
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reposted by
Elaine Chen
J. Emory Parker 🏳️🌈
7 months ago
New from me: Here it is, everything I know about every change I've been monitoring on
data.cdc.gov
plus an archive of every file that's been removed or altered.
www.statnews.com/2025/02/14/t...
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STAT is backing up and monitoring CDC data in real time: See what's changing
STAT is backing up and monitoring CDC data in real time: See what's changing.
https://www.statnews.com/2025/02/14/tracking-cdc-data-changes-trump-executive-order-targets-gender/
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reposted by
Elaine Chen
Helen Branswell 🇨🇦
7 months ago
If you are one of the
#CDC
#HHS
#FDA
#NIH
employees who have learned today that your employment is being abruptly ended, we want to hear from you.
@altcdc.bsky.social
www.statnews.com/2025/02/14/f...
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Are you affected by firings at federal health agencies?
Have you been affected by firings at federal health agencies? @statnews would like to hear from you.
https://www.statnews.com/2025/02/14/firings-federal-health-agencies-cdc-nih-tips/
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reposted by
Elaine Chen
Sarah Owermohle
7 months ago
BREAKING: HHS to fire thousands of public workers on probationary employment this afternoon. Top officials at CDC, NIH, briefed this morning.
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reposted by
Elaine Chen
Usha Lee McFarling
7 months ago
As outcry builds over Trump cuts to NIH payments, drugmakers are MIA
www.statnews.com/2025/02/11/n...
by
@adamfeuerstein.bsky.social
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As outcry builds over Trump cuts to NIH payments, drugmakers are MIA
Drugmakers — major beneficiaries of NIH-backed university research — have been largely silence on the Trump administration's cuts to agency research payments.
https://www.statnews.com/2025/02/11/nih-payment-costs-trump-pharma-industry-biotech/
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reposted by
Elaine Chen
Brittany Trang
8 months ago
🚨 Excited to officially announce I'm writing a new newsletter for
@statnews.com
! AI Prognosis starts Feb 12. It's all about AI in healthcare, medicine & biotech. (If you sign up before Jan 20, you'll get the first 4 issues free, even if you don't have STAT+!)
www.statnews.com/signup/ai-pr...
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reposted by
Elaine Chen
Megan Molteni
8 months ago
Friday night news from
@jonathanwosen.bsky.social
,
@usha.bsky.social
,
@jasonmast.bsky.social
and myself. Story is developing and will be updated
www.statnews.com/2025/02/07/n...
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NIH plans to slash support for indirect research costs, sending shockwaves through science
The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%
https://www.statnews.com/2025/02/07/nih-slashes-indirect-costs-on-all-grants-to-15-percent-trump/
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Trump administration allows some global aid to restart, but concerns remain on impact of USAID shutdown
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Trump administration allows some global aid to restart, but concerns remain on impact of USAID shutdown
The Trump administration on Friday said global malaria aid can restart, but it was unclear how quickly the money would start flowing again.
https://www.statnews.com/2025/02/07/trump-usaid-malaria-tuberculosis-funding-restored-waiver-granted-foreign-aid-freeze/
8 months ago
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reposted by
Elaine Chen
Lizzy Lawrence
8 months ago
What brain drain could look like at the FDA, new from me:
www.statnews.com/2025/02/07/f...
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Experts fear disruptions at FDA as Trump offers buyouts and layoff reports swirl
The FDA is always trying to staff up, and already struggles to fulfill some duties.
https://www.statnews.com/2025/02/07/fda-disruption-trump-federal-buyouts-layoffs-reports-doge/
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Lawmakers ask the FDA to review Hims’ Super Bowl ad for "misleading" patients, foreshadow that they plan to introduce legislation to address ads that omit safety info, via
@mariojoze.bsky.social
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Lawmakers ask FDA to review Hims’ Super Bowl ad for ‘misleading’ patients
Two senators wrote to the FDA Friday about the Hims Super Bowl ad, which they said misleads patients about compounded weight loss drugs.
https://www.statnews.com/2025/02/07/hims-hers-super-bowl-ad-weight-loss-drugs-lawmakers-fda/
8 months ago
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reposted by
Elaine Chen
O. Rose Broderick
8 months ago
Week two of the Trump administration is underway. If you want to understand the ongoing chaos in federal health agencies, follow me and my
@statnews.com
colleagues.
go.bsky.app/7odqGRR
add a skeleton here at some point
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reposted by
Elaine Chen
anil oza
8 months ago
my colleagues
@statnews.com
& I are continuing to report on changes to NIH and other federal agencies if you are at an event/study section etc that is canceled or changed do reach out you can reach me here, email (anil{dot}oza{at}statnews.com) or signal (aniloza.16)
add a skeleton here at some point
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Eli Lilly is considering offering more doses of its obesity drug Zepbound in vials at lower cost The CEO acknowledged to us that some people have turned to compounding due to "real cost pressures" and the current entry price of the vials can be "too high"
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Eli Lilly is considering offering more Zepbound doses in vials at lower cost
Eli Lilly's CEO says the company is considering offering more Zepbound doses in vials at lower cost.
https://www.statnews.com/2025/01/15/zepbound-vials-doses-eli-lilly-dave-ricks-interview/
8 months ago
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reposted by
Elaine Chen
Bob Herman
8 months ago
Good morning from
#JPM25
, where some companies like Cigna, Centene, Oscar, and Walgreens have dropped out of the conference.
www.statnews.com/2025/01/13/j...
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Cigna, Centene, Walgreens drop out of J.P. Morgan conference
Cigna and Centene were among a dozen companies that appeared on the initial JPM agenda that have bowed out of the conference.
https://www.statnews.com/2025/01/13/jp-morgan-centene-cigna-walgreens-bow-out-united-healthcare-brian-thompson/
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FDA shifts toward the importance of obesity drugs in new guidance It calls obesity a disease instead of a health risk. It removes language that lifestyle changes are “the cornerstone” of obesity management. And it eases recommendations for trials in kids
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In debate over obesity medications, FDA shifts toward importance of drugs in subtle ways
In the debate over weight loss medications, the FDA appears to have shifted toward the importance of drugs.
https://www.statnews.com/2025/01/10/weight-loss-obesity-drugs-fda-guidance/
9 months ago
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reposted by
Elaine Chen
Lizzy Lawrence
9 months ago
BREAKING: Patrizia Cavazzoni, head of FDA’s drug center, to leave the agency
www.statnews.com/2025/01/10/f...
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Patrizia Cavazzoni, head of FDA’s drug center, to leave the agency
Patrizia Cavazzoni, leader of the FDAs Center for Drug Evaluation and Research, is leaving the agency on Jan. 18
https://www.statnews.com/2025/01/10/fda-patrizia-cavazzoni-drug-center-head-leaving/
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On this week's podcast, we preview JPM and a potential surge in deal-making this year. Stay tuned for next week's episode — we'll be recording in San Francisco and bringing on Eli Lilly CEO Dave Ricks.
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Pharma's big patent cliff, more obesity fundraising, and a failed ALS study
STAT reporters discuss why a looming patent cliff could lead to more pharmaceutical deal-making and a new obesity startup.
https://www.statnews.com/2025/01/09/readout-loud-pharma-patents-jpm-verdiva-obesity-calico/
9 months ago
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The advent of generic liraglutide (an older GLP-1 drug) could help Medicare negotiate a lower price for Ozempic and Wegovy — via my colleague John Wilkerson
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Generic GLP-1 drugs could help Medicare drive a harder bargain for Ozempic and Wegovy
Medicare is already spending billions on drugs like Ozempic, and Biden recently proposed expanding access to obesity treatments.
https://www.statnews.com/2025/01/07/generic-glp-1-drugs-help-medicare-price-negotiation-semaglutide-ozempic-wegovy/
9 months ago
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reposted by
Elaine Chen
9 months ago
In a less-than-ideal turn of events, I was affected by the layoffs
@statnews.bsky.social
upon returning from maternity leave. I have loved my time at STAT and am heartbroken, but here: able and willing to work, open to all opportunities. Find me at
[email protected]
!
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reposted by
Elaine Chen
Theresa Gaffney
9 months ago
I wrote about gender-affirming surgery — what it means to the people that get it, its evolution as a professional specialty in the U.S., and how the incoming administration could put all of that at risk:
www.statnews.com/2024/12/23/g...
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What Novo Nordisk’s disappointing trial results mean for the obesity drug market — I break down the key implications of today's CagriSema results
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What Novo Nordisk’s disappointing trial results mean for the obesity drug market
New clinical trial data from Novo Nordisk raise questions for the broad landscape of obesity drug development and the way investors view emerging candidates.
https://www.statnews.com/2024/12/20/novo-nordisk-cagrisema-obesity-drug-market-impact/
9 months ago
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A closely watched next-gen obesity treatment from Novo Nordisk misses the mark in a pivotal trial, results that cast into doubt the future competitiveness of the company in the booming weight loss market.
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Next-gen obesity treatment from Novo Nordisk misses mark in pivotal trial
Novo Nordisk’s next-gen obesity drug led patients to lose substantial weight, but fell short of expectations.
https://www.statnews.com/2024/12/20/novo-nordisk-cagrisema-obesity-wegovy/
9 months ago
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The FDA said today that the tirzepatide shortage is over, reiterating its decision in October, but pharmacies still seem to have trouble ordering enough of the drug. One patient in Phoenix: The shortage “wasn’t resolved then, and it isn’t resolved now.”
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FDA confirms shortage of weight loss drug tirzepatide is over, gives compounders a grace period
The FDA on Thursday confirmed that a shortage of Eli Lilly’s obesity drug tirzepatide has been resolved, a move that will put a stop to companies making cheaper copies.
https://www.statnews.com/2024/12/19/fda-confirms-tirzepatide-shortage-compounders/
9 months ago
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Last podcast of the year -- we chat about how Marty Makary might lead the FDA w/
@lizzylawrence.bsky.social
, our burning biotech Qs for next year, and our favorite holiday potato dishes
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A deep dive on Makary, Vertex's pain data, & 2025 predictions
STAT's Readout LOUD podcast discusses Trump's pick for FDA chief and offers a year-end round of questions and predictions about biopharma in 2025.
https://www.statnews.com/2024/12/19/deep-dive-makary-fda-vertex-pain-data-biopharma-2025-predictions/
9 months ago
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reposted by
Elaine Chen
Lizzy Lawrence
9 months ago
NEW: Some consider him a fearless truth-teller with a deep respect for science. Others consider him a contrarian for contrarian’s sake, opining on matters for political clout. Which Marty Makary would run the FDA?
www.statnews.com/2024/12/17/m...
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Truth-teller or reflexive contrarian: Which Marty Makary would run the FDA?
Pancreatic surgeon Marty Makary is a long-time critic of the medical establishment who's now set to regulate food, drugs, and medical devices at the FDA.
https://www.statnews.com/2024/12/17/marty-makary-trump-pick-to-run-the-fda-commissioner-profile/
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Novo Holdings is set to close its $16.5 billion acquisition of Catalent after FTC declines to challenge the deal
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Novo Holdings is set to close its $16.5 billion acquisition of Catalent after FTC declines to challenge the deal
Catalent is an attractive target because it is a subcontractor that already helps manufacture the Wegovy anti-obesity drug
https://www.statnews.com/pharmalot/2024/12/14/novo-catalent-deal-obesity-diabetes-wegovy-lilly-ftc-antitrust/?utm_medium=email&_hsenc=p2ANqtz--TxQogLDA9AZn4D_avVmd32WPj2wy9ubN8F-8N5jLbRqvDEV1XHcTNocofGVR9SyqOB73HRQ--Gi4jXsRjGXKCANfVIQ&_hsmi=338566482&utm_content=338566482&utm_source=hs_email
9 months ago
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reposted by
Elaine Chen
Alex Hogan
10 months ago
This has implications for the wider alternative market for GLP-1s, where tele-healths are offering both brand name and compounded copies of drugs like Zepbound and Wegovy. I recently did an explainer on how this whole marketplace works.
youtu.be/2w-MCLEtZ10
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How compounding pharmacies can make GLP-1 weight loss drugs
YouTube video by STAT
https://youtu.be/2w-MCLEtZ10
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