🖤 With deep sorrow, we announce the passing of Prof. Dr. Jaime Bosch, President of the Baveno Cooperation. A brilliant scientist, inspiring leader, and dear friend. His immense legacy in hepatology will endure. Rest in peace, Jaime

Celebrated 8 incredible years of Stine Lab with a team lunch today! Grateful for the hard work, discoveries, and camaraderie that made our journey so impactful. Here’s to the science, the memories, and the friendships that last far beyond the lab. #MASLD #Research

The muscle–adipose–liver axis is critical, yet underrecognized, in #MASLD. Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis. Its time to standardize definitions and intervene early: link.springer.com/article/10.1...

📢Great to write this review for Hep Comms with Matt Armstrong & @jonathanstinemd.bsky.social 💪We've covered everything you need to know about #Muscle & #MASLD - Insulin resistance - Sarcopenia - Myosteatosis - Impact of weight loss drugs - Benefits of exercise 🔗 shorturl.at/aFO1Q #LiverSky

It was an absolute delight to contribute to this high-impact work with @tom-marjot.bsky.social and @mattarmstrong95.bsky.social in which we review all things #MASLD and #Muscle! If you're looking for holiday weekend reading, look no further: journals.lww.com/hepcomm/page... @ebtapper.bsky.social

Choose to walk 🚶‍♂️ or cycle 🚲 whenever possible. It can help improve: ♥️ your heart, 😇 your mind, 🌏 and the planet. Learn more 👉 bit.ly/43eExcc #RoadSafety #BeActive

New review out! 🧬 Autophagy plays a key role in #MASLD, regulating lipid metabolism, insulin sensitivity & fibrosis. But effects vary by cell type. Precision targeting is key. Great work led by Prashant Nighot and Kofi Clarke Read here: sciencedirect.com/science/arti...

Heading to the PA State Capitol tomorrow to advocate for continued funding of PA CURE program. This is critical for advancing clinical and biomedical research in PA. This investment saves lives and is even more important given the status of federal research funding. #ResearchMatters #PublicHealth

#Exercise may protect the liver by blocking ferroptosis, a key cell death pathway in #MASLD. 🏃‍♀️🧬 New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence pubmed.ncbi.nlm.nih.gov/40206477/

Most people haven’t heard of this test, which is available in the US. It accurately predicts Alzheimer’s (not just if there’s a risk, but when). It is modulated by exercise and likely other lifestyle factors. Here’s (almost) everything we know about it erictopol.substack.com/p/the-breakt...

Ok, I couldn't resist this trend any longer... I had to have ChatGPT make my action figure based on my bio and here is what it generated 😂 😂 😂

🚨Steatotic liver disease driven by senescent hepatocytes 🔑Senescent hepato lose key functions 🧬Defined senescent hepato gene signature 🧩Senescent hepato gene enrichment correlates w/ multi-organ dysfunction 🎯Senolytics target senescent hepato & improve damage www.nature.com/articles/s41...

I join >1900 members of US National Academies of Science, Engineering, and Medicine signing this letter, as individuals, decrying the present thoughtless assault on science, which is against our national interests. docs.google.com/document/d/1... Our health, wealth, and security depend on science.

How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...

🔥🆙 to publish alongside my pre-doc #HannahMohrMS in AP&T where we offer our 🧠🧠🧠 about time restricted feeding and #MASLD including commentary on the recently published CHRONO-NAFLD study Read the full paper here: onlinelibrary.wiley.com/doi/10.1111/...

THIS: The Best Investment You Didn’t Know You Made: How NIH Funding Fuels Innovation and Economic Growth www.amfar.org/news/how-nih...

The liver loves aerobic exercise journals.lww.com/hepcomm/full... #liversky

New paper from us in @jhepatology.bsky.social: www.journal-of-hepatology.eu/article/S016... Causes of death in >13,000 persons with #MASLD - check it out #liversky. So proud of co-senior author Axel Wester and first author medical student Gabriel Issa for the work!

Our March member spotlight is Dr. Pooja Singhal! She discusses the critical role women #GI docs play in assisting the unique needs of female patients, her involvement in the @amergastroassn.bsky.social Women in GI Workshop & more: buff.ly/dFGqZ2d

In these unprecedented dark times for American life science and medical research (no less well beyond biomedicine), my coping mechanism is to laser focus on the unremitting and remarkable daily advances, and the fervent hope these will not be slowed or interrupted.

Join us for Penn State Health MASH Day on June 12th for a high-yield medical conference covering the latest in MASLD/MASH diagnosis and management. Don't miss expert insights and practical takeaways! Register here: ce.med.psu.edu/mash/ It’s free!

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...

Pretty big turnout at Stand Up for Science, talked with scientists and non-scientists who came to DC from all over.

Today is #WorldObesityDay and a good reminder that obesity is a major driver of #MASLD affecting billions worldwide. The good news? #Lifestyle interventions work! #Exercise can reverse liver fat & improve metabolic health. Let’s turn awareness into action! #ExerciseIsMedicine

Today is #WorldObesityDay. #Obesity is a complex condition and each individual faces distinct needs & challenges. A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE

"Without drastic intervention, 3·80 billion adults over the age of 25 years will have overweight and obesity by 2050." www.thelancet.com/journals/lan... @thelancet.bsky.social

Did you know? 1 in 8 people worldwide are living with obesity. #Obesity can lead to serious health conditions like type 2 diabetes, hypertension & cardiovascular diseases. Learn how to prevent obesity 🔗 bit.ly/3SAcdeE #WorldObesityDay

🎙️ Just finished a great interview with HCPLive on the importance of a #multidisciplinary care model for #MASLD. Collaboration across specialties is key to improving outcomes and redefining liver care! #LiverHealth #TeamApproach 📢 Full thoughts here: www.hcplive.com/view/the-imp...

Presently, an estimated 60-70 million Americans are suffering from GI diseases. That is why consistent and sustainable funding from NIH is necessary to support innovative research and treatment development. Please take a minute to tell Congress to stop NIH cuts! gastro.quorum.us/campaign/109928

In the 📕#RedJournal: Update on Newly Federal Drug Administration-Approved Drug, Resmetirom: A Practical Perspective A. Sidney Barritt, IV, MD, MSCR, FACG & Jonathan G. Stine, MD, MSc 👉 bit.ly/438oCOq @sidbarritt4.bsky.social @jonathanstinemd.bsky.social

New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. https://go.nature.com/4gM6oW4

Federal Register Blackout Blocks NIH Funding www.medpagetoday.com/special-repo...

Vaccines save lives. Share widely. #PedSky #MedSky #Pediatrics #Vaccinessavelives

98% of NIH grants that should have gone out this month, didn't. Despite court orders 'unfreezing' the funds, they are frozen. Biomedical research will grind to a halt. Clinical trials will end. All for no reason: the total impact on the US budget is miniscule

Had a great time on Your Health First with Dr. Joe Galotti discussing how exercise improves fatty liver, even without weight loss! #LiverHealth #ExerciseIsMedicine Listen here: podcasts.apple.com/us/podcast/j...

Defying defiance to the laws. Good for NIH!

Happy #InternationalDayofWomenandGirlsinScience! 🌟 Today, we celebrate the brilliant and innovative women pushing boundaries in research. A special shoutout to the incredible women in the Stine Lab, whose talent and dedication drive scientific discovery daily! #WomenInScience

BREAKING: In response to doctors' lawsuit, Judge John Bates, a George W. Bush appointee, orders CDC, NIH, and FDA to put back up websites and datasets cited by the doctors in their lawsuit as having been relied upon and pulled down without notice. storage.courtlistener.com/recap/gov.us...

STAT story www.statnews.com/2025/02/11/j...

A Direct Hit, by @holdenthorp.bsky.social @science.org www.science.org/doi/full/10.... "This is a moment to unite."

It is International Day of Women and Girls in Science. Gagandeep Kang’s research on enteric infections has contributed to the rotavirus vaccine rollout in #India, protecting millions of children and shaping a healthier future. for all. 🔬 #WomenInScience #WomenInSTEM

Today is International Day of Women & Girls in Science. Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM

How to get 146% return on investment? The NIH. That's just the economic benefit. Biomedical research promotes human health.

This 15% cap on indirect costs for NIH grants is yet another example of the 'unprecedented' moves the Trump administration is taking to change how science is done that I wrote about today. www.npr.org/sections/sho...

Wherein @jonathanstinemd.bsky.social spills all his secrets for improving outcomes in #masld journals.lww.com/hepcomm/full... #liversky

For those of you who missed the broadcast ♫ on @iHeartRadio with @drjoegalati, the podcast is available now: www.iheart.com/podcast/44-y...

There's widespread confusion and fear among scientists and doctors on the sprawling National Institutes of Health campus and at institutions dependent on the agency's funding.

Our multidisciplinary care model for adults with fibrotic #MASH leads to clinically meaningful improvements in #liver and metabolic health: 🔹 Individualized Rx plans 🔹 Lifestyle intervention + pharmacotherapy 🔹 Inclusion of EPs, obesity medicine journals.lww.com/hepcomm/page...