I am thrilled to announce that I will be starting my lab at @washumedicine.bsky.social, Department of Pathology & Immunology as an Assistant Professor this month. The lab will study the role of innate immunity in neurodegeneration and brain aging. We'll be hiring at all levels. Details soon!

My postdoc work from the Gan Lab is out now! 👇 The incredible @sarahnaguib.bsky.social and @chloelopezlee.bsky.social drove this project to completion and I'm so proud of the work put in and grateful to all the contributions from Gan lab members and collaborators. 🧠

Grateful for the opportunity to co-lead this study with @liganlab.bsky.social, @sarahnaguib.bsky.social, and @ertorres.bsky.social! We peel back layers of the protective Christchurch mutation to identify underlying mechanisms and transfer protection to non-Christchurch models with neurotoxic tau 💫

🚨Our new paper is out!🚨 We uncover a protective mechanism of the rare APOE3 Christchurch (R136S) mutation against tauopathy—by suppressing microglial cGAS–STING–interferon (IFN) pathway, a key inflammatory axis triggered by tau. www.sciencedirect.com/science/arti...

And the full paper is here - www.pnas.org/doi/abs/10.1.... Thanks to Dave and Joseph for the nice coverage!